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The map label for this gene is tlyC [H]

Identifier: 170747070

GI number: 170747070

Start: 683746

End: 684879

Strand: Reverse

Name: tlyC [H]

Synonym: Mrad2831_0636

Alternate gene names: 170747070

Gene position: 684879-683746 (Counterclockwise)

Preceding gene: 170747071

Following gene: 170747069

Centisome position: 11.27

GC content: 73.37

Gene sequence:

>1134_bases
ATGAGCAACGATCGAAGTCGCGGCGCGGCCCTGGCCGCGCCCAGTTCCGCCGAGGGCGAATCCCAGCACCGGGAGCCCTG
GTACGACCGCCTGCTCCAGGCGCTCCACCTCAAGCCGCGCGATTCGCTGCGCGAGGGTCTTGAGGAGGCGCTGGCGGAGC
CGGATGCCGGCGAGAGCGGCCTCACCCCGCTCGAGCGTGTCATGCTCAAGAACGTCCTCGGCCTGCACAAGGTGCGCGTC
GACGACGTGATGGTCCCCCGGGCCGACATCGTCGCCGTCTCGAACGACACGAGCCTCGGCGACCTGCTCAAGCTGTTCCG
CACGGCCGGCCATTCCCGGCTGCCGGTCTACGGCGAGACCCTCGACGATCCCCGCGGCATGGTCCACATCCGCGACCTCG
TCGACCACATCGCCGCCAAGGCCGAGCCGGCCCGGCGCAGCGCGCCCGCCGTCGCGAAGCCGGTCGAGGTCGCGGTCGAC
GGCGCGGCGGACACGCCGGCCGCCCCGCGCCCGCGCCGGCCCGCGGCGCGCCTGCCGCGCGGGCTGGACCTCGGCAAGGT
CGACCTGACGACGACGCTCGCGGCGGCCCGTATCCAGCGGCCGGTCCTGTTCGTGCCGCCTTCCATGCCGGCGATCGACC
TGCTGGTGCGGATGCAGGCCACCCGCACCCACATGGCGCTGGTCATCGACGAGTACGGCGGCACAGACGGGCTGATCTCC
ATCGAGGATCTGATCGAGGTCGTGGTCGGCGACATCGAGGACGAGCACGACGTCGCCGAGGACAAGCACGTCCAGCGGGT
CGAGGGCGAGGGCGAGGTCTTCGTGGCCGACGCGCGCACGCCGCTGGCCGAGGTCTCCGAGGTGACGGGCGTCGACCTCG
TCGCGGCCGTCGGCGAGATGGCCGAGGAGATCGACACGCTGGGCGGCATGATCGTGACCCTGGCGGGCCGCGTTCCCTCG
CGCGGCGAGCTGATCGCCGGCCCGGGCGACCTCGAGTTCGAGGTGCTCGACGCCGATCCGCGGCGCCTGAAGCGCCTCCG
GTTCCACAAGGGCGCGGCGCGGATCGGCAACGTCGTGCCGCTCGCCCTGCCCCCGCCCGCGAACGCCCCGGTCGCCGAGA
CGCCGCACCCGTGA

Upstream 100 bases:

>100_bases
TGCCATGGAAGCCCTCGAGGTCGCGGCACTCGCGACCCTCGGCATCCCGGATCCCTATGCCTGAGCGCGCGACGTCCGAG
CGACCCCAGACCCGAGAGAC

Downstream 100 bases:

>100_bases
CGGTCGCGGCGTGACGAGCTTGGCGGACGGTTTCGCCCGGTCGCCCGCGGCGGCCGGCGCGTCGATGCGCGGGCCGGTTC
CGGGTCCGATGTCCGATCCG

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSNDRSRGAALAAPSSAEGESQHREPWYDRLLQALHLKPRDSLREGLEEALAEPDAGESGLTPLERVMLKNVLGLHKVRV
DDVMVPRADIVAVSNDTSLGDLLKLFRTAGHSRLPVYGETLDDPRGMVHIRDLVDHIAAKAEPARRSAPAVAKPVEVAVD
GAADTPAAPRPRRPAARLPRGLDLGKVDLTTTLAAARIQRPVLFVPPSMPAIDLLVRMQATRTHMALVIDEYGGTDGLIS
IEDLIEVVVGDIEDEHDVAEDKHVQRVEGEGEVFVADARTPLAEVSEVTGVDLVAAVGEMAEEIDTLGGMIVTLAGRVPS
RGELIAGPGDLEFEVLDADPRRLKRLRFHKGAARIGNVVPLALPPPANAPVAETPHP

Sequences:

>Translated_377_residues
MSNDRSRGAALAAPSSAEGESQHREPWYDRLLQALHLKPRDSLREGLEEALAEPDAGESGLTPLERVMLKNVLGLHKVRV
DDVMVPRADIVAVSNDTSLGDLLKLFRTAGHSRLPVYGETLDDPRGMVHIRDLVDHIAAKAEPARRSAPAVAKPVEVAVD
GAADTPAAPRPRRPAARLPRGLDLGKVDLTTTLAAARIQRPVLFVPPSMPAIDLLVRMQATRTHMALVIDEYGGTDGLIS
IEDLIEVVVGDIEDEHDVAEDKHVQRVEGEGEVFVADARTPLAEVSEVTGVDLVAAVGEMAEEIDTLGGMIVTLAGRVPS
RGELIAGPGDLEFEVLDADPRRLKRLRFHKGAARIGNVVPLALPPPANAPVAETPHP
>Mature_376_residues
SNDRSRGAALAAPSSAEGESQHREPWYDRLLQALHLKPRDSLREGLEEALAEPDAGESGLTPLERVMLKNVLGLHKVRVD
DVMVPRADIVAVSNDTSLGDLLKLFRTAGHSRLPVYGETLDDPRGMVHIRDLVDHIAAKAEPARRSAPAVAKPVEVAVDG
AADTPAAPRPRRPAARLPRGLDLGKVDLTTTLAAARIQRPVLFVPPSMPAIDLLVRMQATRTHMALVIDEYGGTDGLISI
EDLIEVVVGDIEDEHDVAEDKHVQRVEGEGEVFVADARTPLAEVSEVTGVDLVAAVGEMAEEIDTLGGMIVTLAGRVPSR
GELIAGPGDLEFEVLDADPRRLKRLRFHKGAARIGNVVPLALPPPANAPVAETPHP

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=259, Percent_Identity=24.3243243243243, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786879, Length=324, Percent_Identity=26.5432098765432, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI87082033, Length=292, Percent_Identity=21.9178082191781, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 40412; Mature: 40280

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDRSRGAALAAPSSAEGESQHREPWYDRLLQALHLKPRDSLREGLEEALAEPDAGESG
CCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
LTPLERVMLKNVLGLHKVRVDDVMVPRADIVAVSNDTSLGDLLKLFRTAGHSRLPVYGET
CCHHHHHHHHHHHHHHHEEHHHEECCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCC
LDDPRGMVHIRDLVDHIAAKAEPARRSAPAVAKPVEVAVDGAADTPAAPRPRRPAARLPR
CCCCCCEEHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCC
GLDLGKVDLTTTLAAARIQRPVLFVPPSMPAIDLLVRMQATRTHMALVIDEYGGTDGLIS
CCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCEEEEEEECCCCCCCEEE
IEDLIEVVVGDIEDEHDVAEDKHVQRVEGEGEVFVADARTPLAEVSEVTGVDLVAAVGEM
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCHHHHHHHHHH
AEEIDTLGGMIVTLAGRVPSRGELIAGPGDLEFEVLDADPRRLKRLRFHKGAARIGNVVP
HHHHHHHCCEEEEEECCCCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHCHHHHCCEEE
LALPPPANAPVAETPHP
EECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNDRSRGAALAAPSSAEGESQHREPWYDRLLQALHLKPRDSLREGLEEALAEPDAGESG
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
LTPLERVMLKNVLGLHKVRVDDVMVPRADIVAVSNDTSLGDLLKLFRTAGHSRLPVYGET
CCHHHHHHHHHHHHHHHEEHHHEECCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCC
LDDPRGMVHIRDLVDHIAAKAEPARRSAPAVAKPVEVAVDGAADTPAAPRPRRPAARLPR
CCCCCCEEHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCC
GLDLGKVDLTTTLAAARIQRPVLFVPPSMPAIDLLVRMQATRTHMALVIDEYGGTDGLIS
CCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCEEEEEEECCCCCCCEEE
IEDLIEVVVGDIEDEHDVAEDKHVQRVEGEGEVFVADARTPLAEVSEVTGVDLVAAVGEM
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCHHHHHHHHHH
AEEIDTLGGMIVTLAGRVPSRGELIAGPGDLEFEVLDADPRRLKRLRFHKGAARIGNVVP
HHHHHHHCCEEEEEECCCCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHCHHHHCCEEE
LALPPPANAPVAETPHP
EECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10531273 [H]