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The map label for this gene is mtgA [H]

Identifier: 170747045

GI number: 170747045

Start: 654135

End: 654785

Strand: Reverse

Name: mtgA [H]

Synonym: Mrad2831_0611

Alternate gene names: 170747045

Gene position: 654785-654135 (Counterclockwise)

Preceding gene: 170747047

Following gene: 170747044

Centisome position: 10.77

GC content: 71.27

Gene sequence:

>651_bases
GTGGGAGCGCTGCTGCTGCTCCCCGCCGTCGGGTTCGTCCTCGCGCTGACGTTGGCGCTCGTCTATAGCGCGGTGATGCC
GCCGTCGACCCTGATGCTGGGACGGTGGTTGACGCTTCAGCCGGTGAGCCGCGATCCGGTCCCGCTCTCCGCCATCGCGC
CGGCCCTGCCCCAGGCCGTGATCGCCTCGGAGGATCAGCGCTTCTGCCTGGATCACGGCGTCGATTTCGGCGCGATCCGC
GACGTGGTCGAGGACGAGGACTCGCCGAGCCGCGGCGCCTCCACGATCGCCATGCAGACGGTCAAGAACGTCTTCCTGTG
GCCCGGCCGCTCCTACATCCGCAAGGCCATCGAGATCCCGCTGGCGCTGGCGCTCGACACGCTCTGGGGCAAGCGCCGCA
TGATGGAGATCTACCTCAACGTCGCCGAGTGGGGCGACGGGATCTACGGTGCGCAGGCCGCGAGCCGGCACTGGTTCGGC
AAGGACGCGAGCCGGTTGACCCGCAACGAGGCCGCCCTCCTCGCCGCCGTCCTGCCGAACCCGATCACCCGCAGCGCCGG
CCGGCCCTCTCCCGGCGTGCGCCGACGGGCCGCGCGGATCCAGGCCATGATGGGGCAGATCGACGGGCTGACGGGCTGCC
TGCGGCGGTAG

Upstream 100 bases:

>100_bases
GGACGGACTCACGGTGGACGGGGCTCGACGCAGGCGGGAGACGGCAGGTCGCGACCTTCCGCTCGCGCGCCCGCGCCGTT
CCCGCCGCGTCCGCCAGGCC

Downstream 100 bases:

>100_bases
CAGGGGGCGGTGCGCCTCTGTAAGACGGGCCTTCCAAGCGTGAGACCCGGGACCGACCCACGATGAGCGATGCCGTTTAC
GACCTGAGCCTGGAGCGCAT

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MGALLLLPAVGFVLALTLALVYSAVMPPSTLMLGRWLTLQPVSRDPVPLSAIAPALPQAVIASEDQRFCLDHGVDFGAIR
DVVEDEDSPSRGASTIAMQTVKNVFLWPGRSYIRKAIEIPLALALDTLWGKRRMMEIYLNVAEWGDGIYGAQAASRHWFG
KDASRLTRNEAALLAAVLPNPITRSAGRPSPGVRRRAARIQAMMGQIDGLTGCLRR

Sequences:

>Translated_216_residues
MGALLLLPAVGFVLALTLALVYSAVMPPSTLMLGRWLTLQPVSRDPVPLSAIAPALPQAVIASEDQRFCLDHGVDFGAIR
DVVEDEDSPSRGASTIAMQTVKNVFLWPGRSYIRKAIEIPLALALDTLWGKRRMMEIYLNVAEWGDGIYGAQAASRHWFG
KDASRLTRNEAALLAAVLPNPITRSAGRPSPGVRRRAARIQAMMGQIDGLTGCLRR
>Mature_215_residues
GALLLLPAVGFVLALTLALVYSAVMPPSTLMLGRWLTLQPVSRDPVPLSAIAPALPQAVIASEDQRFCLDHGVDFGAIRD
VVEDEDSPSRGASTIAMQTVKNVFLWPGRSYIRKAIEIPLALALDTLWGKRRMMEIYLNVAEWGDGIYGAQAASRHWFGK
DASRLTRNEAALLAAVLPNPITRSAGRPSPGVRRRAARIQAMMGQIDGLTGCLRR

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI1789601, Length=202, Percent_Identity=45.049504950495, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI87082258, Length=143, Percent_Identity=41.2587412587413, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1786343, Length=139, Percent_Identity=35.2517985611511, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 23458; Mature: 23327

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALLLLPAVGFVLALTLALVYSAVMPPSTLMLGRWLTLQPVSRDPVPLSAIAPALPQAV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHH
IASEDQRFCLDHGVDFGAIRDVVEDEDSPSRGASTIAMQTVKNVFLWPGRSYIRKAIEIP
HHCCCCHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LALALDTLWGKRRMMEIYLNVAEWGDGIYGAQAASRHWFGKDASRLTRNEAALLAAVLPN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PITRSAGRPSPGVRRRAARIQAMMGQIDGLTGCLRR
CHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GALLLLPAVGFVLALTLALVYSAVMPPSTLMLGRWLTLQPVSRDPVPLSAIAPALPQAV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHH
IASEDQRFCLDHGVDFGAIRDVVEDEDSPSRGASTIAMQTVKNVFLWPGRSYIRKAIEIP
HHCCCCHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LALALDTLWGKRRMMEIYLNVAEWGDGIYGAQAASRHWFGKDASRLTRNEAALLAAVLPN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PITRSAGRPSPGVRRRAARIQAMMGQIDGLTGCLRR
CHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]