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The map label for this gene is resE [H]

Identifier: 170746955

GI number: 170746955

Start: 557309

End: 558955

Strand: Reverse

Name: resE [H]

Synonym: Mrad2831_0521

Alternate gene names: 170746955

Gene position: 558955-557309 (Counterclockwise)

Preceding gene: 170746956

Following gene: 170746954

Centisome position: 9.2

GC content: 75.41

Gene sequence:

>1647_bases
ATGCGCTCGCTGAAGGTCCGCTTCGCGCTGCTGCTCGGCGGCACCGCCATCGTGGTGGTGCTGGCCGCCGCGGCCGCGCT
GGCGGCGATCGGGGCGGCGGAGCGGACCGTCGACCGGACCCTCGAGGCTCAGCGGCGCCTGGAGCTGCTGGCCGAGCTGT
CCGGCCGCCTCACCCAGTTCGGTCTCGCGGCCGTGGAGACCGTCGGCAACCCCGACGGCCAGCCCGAGGCGATGGCGATC
GCCCGCGACAACGCCGATCGGGCCCTGACCACCGTGGACGAGGCGCTCGCCAAGAGCTTCCCGCCGAGCGACGACCCGGC
CGACCGGATGCAGTACGCCGCGCGCACCCGCCCGATGGCGCAGCTGCGCGCGGCCCGCGCGGTGCTGGACCGGCAGGTCT
CGCTGATCAGCCGCCAGACCGATCAGGAGCGGCGTCAGGACGCGATCAAGGGCGCGCTCAACGGCTTCGGCGCCATGACC
GGCCAGCCCCTCTCCTTCCTCATCGAGGCCGAGCGGCGCAGCATGGCGCTCGGCTCCGAGCAGGCCCGGGCGCTGTCCGA
GCGCCTGCGGGTGGCCGCCGCGGCCGCGGTGGCGGCGGCCCTGGTGCTGCTGGCGATCCTGTACCGGGGCGTCACCCGGC
CGACCCTGGCGCGCATCGAGGAGGTCCGCCGCGCCGCGAGCGCCATCGGCCACGGCGCCCTCGACACGCGCCTCTCCGTC
GCCACGCGGGACGAGCTCGGCCTGCTGATGACCAACGTCAACCGCATGGCCGCCCGGCTGGCACGGCGGGAATCGCGGGT
CGCGGCCGACCGGGCGGCGCTGGAGGACACGGTGGCGGCGCGCACCGCCGACCTGCGCGCCGCCAACGCCCGGCTGGAGG
CGGTCGATCAGTCCCGCCGCCGCTTCTTCGCCGATGTCAGCCACGAGCTGCGCACGCCCCTGACGGTGATCCTGGGCGAG
TGCGACCTCGCCCTGCGCGGCGCGTCCCGGGGCGCCGATCCGGGGCCGGTCTTCGCCACGATCAAGAAGCGGGCGCAGCG
CCTCAAGCTGCGCGTCGAGGACCTTCTCCGCGTCGCCCGCTCGGAGTCCGGCGAGATCGCGTTCGACAAGCGCCGTCTGG
GGCTCGCCCAAGTCCTCGCGGAGGCCGTGGACAACATGAGCTCCGAGGCGGCGCGCCGCCGGGTCGGTCTCACCCTCGAT
CCGGGCAGCCGGGACGTCGAGAGCCTCGCCGACCGCGAGTGGATGCGCCAGACGGTCGAGAGCCTCGTCGACAACGCGCT
CCGCCACGCCGCCGGCCTCACCCGGGTCGAGGTCGCCCTGGCGGCAGGTCCGGGACCGGTCGGGCGGATCACCATCACGG
ATGATGGTCCCGGCTTCGGTGCCCCGGAGGAGGCGCTGTTCGAGCGCTTCAAGCGCGGCACGGGCGCCGGGCCGGACGAG
ACCGGGTTCGGCATCGGGCTCGCCCTGGCGCGCTGGATCGTCGAGCAGCACGGCGGCACGATCCGACTCGGGCCCGGGCC
GGACGGACGCGGGGCCCGGGTCACCCTGGACATCCCGGCCTGCGATCCGGCATGGGAAACGGGCGCGGCCGACGGCGCTG
CTGTCGGTGCCCGAGTGGGCGCGCAGGTGAAGGAGTCGGCCGCATGA

Upstream 100 bases:

>100_bases
GGACCTGTGACGACGCCCTCGACGGCACCTTGGTTCGGCGCCCCGGCGGTGCCATGCTCGGGCTCGCCCGCGGAGCGGGA
TTGAGGGCGGGACGGGGACG

Downstream 100 bases:

>100_bases
CGCGGATCCTGATCGTCGAGGACGATATCGACATTCGCGGCCTCCTCGCCCGGGGTCTCGAAGCCGAGGGATTCGAGGTC
GGGACGGCGGCCTGCGTCGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MRSLKVRFALLLGGTAIVVVLAAAAALAAIGAAERTVDRTLEAQRRLELLAELSGRLTQFGLAAVETVGNPDGQPEAMAI
ARDNADRALTTVDEALAKSFPPSDDPADRMQYAARTRPMAQLRAARAVLDRQVSLISRQTDQERRQDAIKGALNGFGAMT
GQPLSFLIEAERRSMALGSEQARALSERLRVAAAAAVAAALVLLAILYRGVTRPTLARIEEVRRAASAIGHGALDTRLSV
ATRDELGLLMTNVNRMAARLARRESRVAADRAALEDTVAARTADLRAANARLEAVDQSRRRFFADVSHELRTPLTVILGE
CDLALRGASRGADPGPVFATIKKRAQRLKLRVEDLLRVARSESGEIAFDKRRLGLAQVLAEAVDNMSSEAARRRVGLTLD
PGSRDVESLADREWMRQTVESLVDNALRHAAGLTRVEVALAAGPGPVGRITITDDGPGFGAPEEALFERFKRGTGAGPDE
TGFGIGLALARWIVEQHGGTIRLGPGPDGRGARVTLDIPACDPAWETGAADGAAVGARVGAQVKESAA

Sequences:

>Translated_548_residues
MRSLKVRFALLLGGTAIVVVLAAAAALAAIGAAERTVDRTLEAQRRLELLAELSGRLTQFGLAAVETVGNPDGQPEAMAI
ARDNADRALTTVDEALAKSFPPSDDPADRMQYAARTRPMAQLRAARAVLDRQVSLISRQTDQERRQDAIKGALNGFGAMT
GQPLSFLIEAERRSMALGSEQARALSERLRVAAAAAVAAALVLLAILYRGVTRPTLARIEEVRRAASAIGHGALDTRLSV
ATRDELGLLMTNVNRMAARLARRESRVAADRAALEDTVAARTADLRAANARLEAVDQSRRRFFADVSHELRTPLTVILGE
CDLALRGASRGADPGPVFATIKKRAQRLKLRVEDLLRVARSESGEIAFDKRRLGLAQVLAEAVDNMSSEAARRRVGLTLD
PGSRDVESLADREWMRQTVESLVDNALRHAAGLTRVEVALAAGPGPVGRITITDDGPGFGAPEEALFERFKRGTGAGPDE
TGFGIGLALARWIVEQHGGTIRLGPGPDGRGARVTLDIPACDPAWETGAADGAAVGARVGAQVKESAA
>Mature_548_residues
MRSLKVRFALLLGGTAIVVVLAAAAALAAIGAAERTVDRTLEAQRRLELLAELSGRLTQFGLAAVETVGNPDGQPEAMAI
ARDNADRALTTVDEALAKSFPPSDDPADRMQYAARTRPMAQLRAARAVLDRQVSLISRQTDQERRQDAIKGALNGFGAMT
GQPLSFLIEAERRSMALGSEQARALSERLRVAAAAAVAAALVLLAILYRGVTRPTLARIEEVRRAASAIGHGALDTRLSV
ATRDELGLLMTNVNRMAARLARRESRVAADRAALEDTVAARTADLRAANARLEAVDQSRRRFFADVSHELRTPLTVILGE
CDLALRGASRGADPGPVFATIKKRAQRLKLRVEDLLRVARSESGEIAFDKRRLGLAQVLAEAVDNMSSEAARRRVGLTLD
PGSRDVESLADREWMRQTVESLVDNALRHAAGLTRVEVALAAGPGPVGRITITDDGPGFGAPEEALFERFKRGTGAGPDE
TGFGIGLALARWIVEQHGGTIRLGPGPDGRGARVTLDIPACDPAWETGAADGAAVGARVGAQVKESAA

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=310, Percent_Identity=28.3870967741935, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=33.1914893617021, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=31.4159292035398, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789149, Length=542, Percent_Identity=24.3542435424354, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=29.7872340425532, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=28.2700421940928, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=216, Percent_Identity=23.6111111111111, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=259, Percent_Identity=26.6409266409266, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=26.7206477732794, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58252; Mature: 58252

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLKVRFALLLGGTAIVVVLAAAAALAAIGAAERTVDRTLEAQRRLELLAELSGRLTQF
CCCHHEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAAVETVGNPDGQPEAMAIARDNADRALTTVDEALAKSFPPSDDPADRMQYAARTRPMA
HHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHH
QLRAARAVLDRQVSLISRQTDQERRQDAIKGALNGFGAMTGQPLSFLIEAERRSMALGSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHH
QARALSERLRVAAAAAVAAALVLLAILYRGVTRPTLARIEEVRRAASAIGHGALDTRLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
ATRDELGLLMTNVNRMAARLARRESRVAADRAALEDTVAARTADLRAANARLEAVDQSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFFADVSHELRTPLTVILGECDLALRGASRGADPGPVFATIKKRAQRLKLRVEDLLRVAR
HHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SESGEIAFDKRRLGLAQVLAEAVDNMSSEAARRRVGLTLDPGSRDVESLADREWMRQTVE
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHH
SLVDNALRHAAGLTRVEVALAAGPGPVGRITITDDGPGFGAPEEALFERFKRGTGAGPDE
HHHHHHHHHHCCCHHHEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCC
TGFGIGLALARWIVEQHGGTIRLGPGPDGRGARVTLDIPACDPAWETGAADGAAVGARVG
CCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHC
AQVKESAA
CHHHHCCC
>Mature Secondary Structure
MRSLKVRFALLLGGTAIVVVLAAAAALAAIGAAERTVDRTLEAQRRLELLAELSGRLTQF
CCCHHEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAAVETVGNPDGQPEAMAIARDNADRALTTVDEALAKSFPPSDDPADRMQYAARTRPMA
HHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHH
QLRAARAVLDRQVSLISRQTDQERRQDAIKGALNGFGAMTGQPLSFLIEAERRSMALGSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHH
QARALSERLRVAAAAAVAAALVLLAILYRGVTRPTLARIEEVRRAASAIGHGALDTRLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
ATRDELGLLMTNVNRMAARLARRESRVAADRAALEDTVAARTADLRAANARLEAVDQSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFFADVSHELRTPLTVILGECDLALRGASRGADPGPVFATIKKRAQRLKLRVEDLLRVAR
HHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SESGEIAFDKRRLGLAQVLAEAVDNMSSEAARRRVGLTLDPGSRDVESLADREWMRQTVE
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHH
SLVDNALRHAAGLTRVEVALAAGPGPVGRITITDDGPGFGAPEEALFERFKRGTGAGPDE
HHHHHHHHHHCCCHHHEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCC
TGFGIGLALARWIVEQHGGTIRLGPGPDGRGARVTLDIPACDPAWETGAADGAAVGARVG
CCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHC
AQVKESAA
CHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]