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The map label for this gene is mdcB [H]

Identifier: 170746797

GI number: 170746797

Start: 385399

End: 386367

Strand: Reverse

Name: mdcB [H]

Synonym: Mrad2831_0351

Alternate gene names: 170746797

Gene position: 386367-385399 (Counterclockwise)

Preceding gene: 170746798

Following gene: 170746796

Centisome position: 6.36

GC content: 75.54

Gene sequence:

>969_bases
ATGCGCGGGCGCCGCCATCCGGTATACGTCGGACCGCCCGACGCCGCTTCGGCTGCGCTGGCGAAGCCGGGAGGAGGCCC
GACCCTGCGCGACGAACAGAGCCTGACTGCGCCGGATGCCGACGCGTGCCGCGCCGACGCGCCCAGCGCCGGTCGCGTCG
CGGATCTTGCGCACGCGGCGCTCATCGGCGAATTGGAGACATGGCCCAAGCCCGGCCTCGTGAGCCCGGTCGATTCCGGC
AGCCACGACGACATGGATGCGGAGACTCTCCGCCGCAGCGCGGCGGCGATCCGGCCGTTCTTCGCGGAGCTGGTCGCGGC
GGGTGCCCGCGCGGCGGAGATGGCGGATTTGCGGGCCATCGGTCTGAAAGCCGAGATCGCGATGATGCGGGCGACGGGCG
GCGTCAACGCGCATCGGGGCGCGATCTTCTCGCTCGGCCTGATCTGCGCCGCGGCGGGAGCGAAAGGTGAAGGGCACGGT
GTCGGGCGGGCCGGGGCCGAGGCCCTGGCCGAGGCGGTTGGGCATCTCTGGGGGCCGGCGATCAGCCGGGCACCGGTCTC
GGCTGTCAGCCACGGCGGCCGCGCGGCGCGGCGCTTCGGCGTCGGCGGCGCCAGTGCCGAGGCCGCTTCGGGCTTCCCGA
CCATCCGGGCCGTCGGCCTTCCCGCCCTCCGCTTCGGCCGTTCCTGCGCCCCCGGCGATCCCGAGGCGGCGCGCGTGCAC
TGCTTCTTCGCGCTCCTGGCGGTCGTCGATGACACGAATCTCCTGCACCGCGGCGGCGCCGACGGCCTCGTCGGCGCGCG
CGCGGCCGCCGCGACCTTTCTCGACGCCGGCGGCATCGCGGCTCCGGCTTGGCGCGAGCGCGCGGCGGCGATCCACCGCT
CTTTCGTGGCCGCGCGCCTGAGTCCCGGCGGCTGCGCCGATCTCCTCGCCGCGACGCTGCTGCTGGACGCCCTGGCCTCC
GCGCCCTGA

Upstream 100 bases:

>100_bases
TAAGAGTGTGGTCCAGGCGCCCGACCTCTGGCAGCTGCCCGAACGCTTCGTCGGTTCCTTCTAAGTCCGGATAGGCGACC
CCGCGCGGAGACCGTCGCGG

Downstream 100 bases:

>100_bases
CGCGCGAGCAGCCCCGGGTCGCGTCGGTCGCAGTTTCGCGGGTGCGGTCGATACCTACATCCGGATCCTGTTCCCCCTCC
CCCGCCGGACCGCCCGTGAC

Product: triphosphoribosyl-dephospho-CoA synthase MdcB

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRGRRHPVYVGPPDAASAALAKPGGGPTLRDEQSLTAPDADACRADAPSAGRVADLAHAALIGELETWPKPGLVSPVDSG
SHDDMDAETLRRSAAAIRPFFAELVAAGARAAEMADLRAIGLKAEIAMMRATGGVNAHRGAIFSLGLICAAAGAKGEGHG
VGRAGAEALAEAVGHLWGPAISRAPVSAVSHGGRAARRFGVGGASAEAASGFPTIRAVGLPALRFGRSCAPGDPEAARVH
CFFALLAVVDDTNLLHRGGADGLVGARAAAATFLDAGGIAAPAWRERAAAIHRSFVAARLSPGGCADLLAATLLLDALAS
AP

Sequences:

>Translated_322_residues
MRGRRHPVYVGPPDAASAALAKPGGGPTLRDEQSLTAPDADACRADAPSAGRVADLAHAALIGELETWPKPGLVSPVDSG
SHDDMDAETLRRSAAAIRPFFAELVAAGARAAEMADLRAIGLKAEIAMMRATGGVNAHRGAIFSLGLICAAAGAKGEGHG
VGRAGAEALAEAVGHLWGPAISRAPVSAVSHGGRAARRFGVGGASAEAASGFPTIRAVGLPALRFGRSCAPGDPEAARVH
CFFALLAVVDDTNLLHRGGADGLVGARAAAATFLDAGGIAAPAWRERAAAIHRSFVAARLSPGGCADLLAATLLLDALAS
AP
>Mature_322_residues
MRGRRHPVYVGPPDAASAALAKPGGGPTLRDEQSLTAPDADACRADAPSAGRVADLAHAALIGELETWPKPGLVSPVDSG
SHDDMDAETLRRSAAAIRPFFAELVAAGARAAEMADLRAIGLKAEIAMMRATGGVNAHRGAIFSLGLICAAAGAKGEGHG
VGRAGAEALAEAVGHLWGPAISRAPVSAVSHGGRAARRFGVGGASAEAASGFPTIRAVGLPALRFGRSCAPGDPEAARVH
CFFALLAVVDDTNLLHRGGADGLVGARAAAATFLDAGGIAAPAWRERAAAIHRSFVAARLSPGGCADLLAATLLLDALAS
AP

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=268, Percent_Identity=36.9402985074627, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 32217; Mature: 32217

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGRRHPVYVGPPDAASAALAKPGGGPTLRDEQSLTAPDADACRADAPSAGRVADLAHAA
CCCCCCCEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHH
LIGELETWPKPGLVSPVDSGSHDDMDAETLRRSAAAIRPFFAELVAAGARAAEMADLRAI
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GLKAEIAMMRATGGVNAHRGAIFSLGLICAAAGAKGEGHGVGRAGAEALAEAVGHLWGPA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHH
ISRAPVSAVSHGGRAARRFGVGGASAEAASGFPTIRAVGLPALRFGRSCAPGDPEAARVH
HHCCHHHHHHCCCHHHHHHCCCCCCCHHCCCCCCHHHHCCHHHHHCCCCCCCCCHHHHHH
CFFALLAVVDDTNLLHRGGADGLVGARAAAATFLDAGGIAAPAWRERAAAIHRSFVAARL
HHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
SPGGCADLLAATLLLDALASAP
CCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRGRRHPVYVGPPDAASAALAKPGGGPTLRDEQSLTAPDADACRADAPSAGRVADLAHAA
CCCCCCCEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHH
LIGELETWPKPGLVSPVDSGSHDDMDAETLRRSAAAIRPFFAELVAAGARAAEMADLRAI
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GLKAEIAMMRATGGVNAHRGAIFSLGLICAAAGAKGEGHGVGRAGAEALAEAVGHLWGPA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHH
ISRAPVSAVSHGGRAARRFGVGGASAEAASGFPTIRAVGLPALRFGRSCAPGDPEAARVH
HHCCHHHHHHCCCHHHHHHCCCCCCCHHCCCCCCHHHHCCHHHHHCCCCCCCCCHHHHHH
CFFALLAVVDDTNLLHRGGADGLVGARAAAATFLDAGGIAAPAWRERAAAIHRSFVAARL
HHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
SPGGCADLLAATLLLDALASAP
CCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10561613 [H]