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The map label for this gene is gap [H]

Identifier: 170746610

GI number: 170746610

Start: 159097

End: 160101

Strand: Reverse

Name: gap [H]

Synonym: Mrad2831_0160

Alternate gene names: 170746610

Gene position: 160101-159097 (Counterclockwise)

Preceding gene: 170746613

Following gene: 170746609

Centisome position: 2.63

GC content: 67.46

Gene sequence:

>1005_bases
GTGACGAAGGTTGCCATCAACGGGTTCGGACGCATCGGCCGCAACGTCCTGCGGGCGATCGCGGAAGCCGGCCGCAGCGA
CATCGAGGTCGTGGCGATCAACGATCTCGGCCCGGTGGAGACCAACGCCCACCTGCTCCGCTACGATTCCGTGCACGGCC
GCTTCCCTGGCGAGGTCGCGGTCGACGGCGAGTTCCTGGTGGTGAACGGCAAGCGCATCAAGGTCACGGCCGTGCGCAAC
CCGGCCGAGCTGCCGCACCGCGACCTCGGCGTCGACATCGCGCTCGAGTGCACCGGCATCTTCACGTCGAAGGACAAGGC
GAAGGCCCATCTCGACGCCGGCGCCAAGCGCGTCCTCGTCTCGGCCCCGGCCGACGGCGCCGACCTGACGGTGGTCTACG
GCGTGAATCACGACAAGCTCACGGGCGAGCACCACGTCGTGTCGAACGCCTCCTGCACCACGAACTGCCTCGCCCCGGTG
GCGAAGGTGCTGGACGAGGCCGTCGGCATCGAGCGCGGCTTCATGACCACGATCCATTCCTACACCAACGACCAGCCGTC
GCTGGACCAGATGCACAAGGATCTTTACCGGGCCCGCGCCGCGGCGCTCTCGATGATCCCGACCTCGACCGGCGCCGCGA
AGGCCGTCGGCCTCGTGCTTCCGGAGCTCAAGGGCAAGCTCGACGGCACCGCGATCCGCGTGCCGACCCCGAACGTCTCG
GCGGTGGATCTCGTCTTCACGGCCAAGCGCGCGACCACGGTCCAGGAGATCAACGACGCGATCAAGGCCGCCGCTTCCGG
TCCGCTGAAGGGTGTCCTCGGCGTCACCGACCGGCCGAACGTCTCGATCGACTTCAACCACGACCCGCATTCGTCGACCT
TCCACCTCGACCAGACCAAGGTCATGGACGGCGTTCTGGTGCGCATCCTGACCTGGTACGACAACGAGTGGGGCTTCTCG
AACCGCATGGCCGACACGGCCGTCGCGATGGCCAAGCTCATCTGA

Upstream 100 bases:

>100_bases
TCCGGCCCGGCCCGGACGGTATGGCGGGCCGCCGAGACCGCTTCGCGGACCGCTCCCGAGGTCCGGCGCGCGGCGAGCCG
CATCAGGAAGGAGTCACGCC

Downstream 100 bases:

>100_bases
GCTGGACTGCAGCGGTCGCCGCCTCCTGAGAGGCCGGCGGCCGCACTTCTCTTCGGACGGCCTATCTTCGAACCAGGGAC
TCTTCAGGGATGACCGACGC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTKVAINGFGRIGRNVLRAIAEAGRSDIEVVAINDLGPVETNAHLLRYDSVHGRFPGEVAVDGEFLVVNGKRIKVTAVRN
PAELPHRDLGVDIALECTGIFTSKDKAKAHLDAGAKRVLVSAPADGADLTVVYGVNHDKLTGEHHVVSNASCTTNCLAPV
AKVLDEAVGIERGFMTTIHSYTNDQPSLDQMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGTAIRVPTPNVS
AVDLVFTAKRATTVQEINDAIKAAASGPLKGVLGVTDRPNVSIDFNHDPHSSTFHLDQTKVMDGVLVRILTWYDNEWGFS
NRMADTAVAMAKLI

Sequences:

>Translated_334_residues
MTKVAINGFGRIGRNVLRAIAEAGRSDIEVVAINDLGPVETNAHLLRYDSVHGRFPGEVAVDGEFLVVNGKRIKVTAVRN
PAELPHRDLGVDIALECTGIFTSKDKAKAHLDAGAKRVLVSAPADGADLTVVYGVNHDKLTGEHHVVSNASCTTNCLAPV
AKVLDEAVGIERGFMTTIHSYTNDQPSLDQMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGTAIRVPTPNVS
AVDLVFTAKRATTVQEINDAIKAAASGPLKGVLGVTDRPNVSIDFNHDPHSSTFHLDQTKVMDGVLVRILTWYDNEWGFS
NRMADTAVAMAKLI
>Mature_333_residues
TKVAINGFGRIGRNVLRAIAEAGRSDIEVVAINDLGPVETNAHLLRYDSVHGRFPGEVAVDGEFLVVNGKRIKVTAVRNP
AELPHRDLGVDIALECTGIFTSKDKAKAHLDAGAKRVLVSAPADGADLTVVYGVNHDKLTGEHHVVSNASCTTNCLAPVA
KVLDEAVGIERGFMTTIHSYTNDQPSLDQMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGTAIRVPTPNVSA
VDLVFTAKRATTVQEINDAIKAAASGPLKGVLGVTDRPNVSIDFNHDPHSSTFHLDQTKVMDGVLVRILTWYDNEWGFSN
RMADTAVAMAKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=47.4320241691843, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=46.9325153374233, Blast_Score=278, Evalue=4e-75,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=50.1501501501502, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=50.4531722054381, Blast_Score=317, Evalue=7e-88,
Organism=Caenorhabditis elegans, GI17534677, Length=330, Percent_Identity=49.0909090909091, Blast_Score=303, Evalue=6e-83,
Organism=Caenorhabditis elegans, GI17534679, Length=330, Percent_Identity=48.7878787878788, Blast_Score=303, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=48.955223880597, Blast_Score=294, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=330, Percent_Identity=48.7878787878788, Blast_Score=293, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=49.702380952381, Blast_Score=317, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=51.1904761904762, Blast_Score=316, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=49.702380952381, Blast_Score=313, Evalue=2e-86,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=49.5412844036697, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=49.5412844036697, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=49.5412844036697, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=49.5412844036697, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI19922412, Length=337, Percent_Identity=43.9169139465875, Blast_Score=267, Evalue=7e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35683; Mature: 35552

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVAINGFGRIGRNVLRAIAEAGRSDIEVVAINDLGPVETNAHLLRYDSVHGRFPGEVA
CCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCEE
VDGEFLVVNGKRIKVTAVRNPAELPHRDLGVDIALECTGIFTSKDKAKAHLDAGAKRVLV
ECCEEEEEECCEEEEEEECCHHHCCCCCCCEEEEEEEEEEEECCCHHHHHHCCCCEEEEE
SAPADGADLTVVYGVNHDKLTGEHHVVSNASCTTNCLAPVAKVLDEAVGIERGFMTTIHS
ECCCCCCCEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
YTNDQPSLDQMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGTAIRVPTPNVS
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCC
AVDLVFTAKRATTVQEINDAIKAAASGPLKGVLGVTDRPNVSIDFNHDPHSSTFHLDQTK
EEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCCCCEEECCHHH
VMDGVLVRILTWYDNEWGFSNRMADTAVAMAKLI
HHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TKVAINGFGRIGRNVLRAIAEAGRSDIEVVAINDLGPVETNAHLLRYDSVHGRFPGEVA
CEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCEE
VDGEFLVVNGKRIKVTAVRNPAELPHRDLGVDIALECTGIFTSKDKAKAHLDAGAKRVLV
ECCEEEEEECCEEEEEEECCHHHCCCCCCCEEEEEEEEEEEECCCHHHHHHCCCCEEEEE
SAPADGADLTVVYGVNHDKLTGEHHVVSNASCTTNCLAPVAKVLDEAVGIERGFMTTIHS
ECCCCCCCEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
YTNDQPSLDQMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGTAIRVPTPNVS
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCC
AVDLVFTAKRATTVQEINDAIKAAASGPLKGVLGVTDRPNVSIDFNHDPHSSTFHLDQTK
EEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCCCCEEECCHHH
VMDGVLVRILTWYDNEWGFSNRMADTAVAMAKLI
HHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]