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The map label for this gene is eefB [H]

Identifier: 170683789

GI number: 170683789

Start: 1856505

End: 1859612

Strand: Reverse

Name: eefB [H]

Synonym: EcSMS35_1835

Alternate gene names: 170683789

Gene position: 1859612-1856505 (Counterclockwise)

Preceding gene: 170683115

Following gene: 170681888

Centisome position: 36.69

GC content: 51.93

Gene sequence:

>3108_bases
ATGTTTTCGCGCTTTTTTGTTCGCCGCCCGGTCTTTGCCTGGGTTATCGCCATTTTGATTATGTTGGCGGGGATTCTGGC
TATTCGCACATTACCCGTCGCGCAATATCCTGACGTTGCACCGCCGACCATTAAAATTTCAGCCACTTATACTGGTGCTT
CTGCCGAAACGCTGGAGAACAGCGTGACTCAGGTTATCGAGCAACAACTCACTGGGCTTGATAATTTACTCTATTTCAGC
TCAACCAGTAGCTCTGATGGTTCGGTCAGTATTAATGTGACCTTTGAACAAGGTACCGATCCAGATACTGCACAGGTTCA
GGTGCAGAATAAAATTCAGCAGGCGGAGTCGCGCCTACCCAGCGAAGTGCAGCAAACGGGTGTTACGGTGGAGAAATCAC
AAAGCAACTTTTTGCTGATTGCTGCCGTGTATGACACCACTGACAAAGCCTCCAGTTCGGATATCGCCGACTGGTTGGTC
AGTAACGTTCAGGACCCGCTGGCGCGTGTTGAAGGTGTGGGGAGTCTGCAAGTCTTTGGCGCGGAATACGCTATGCGCAT
CTGGCTTGACCCGGCCAAACTGGCGTCTTACTCGCTAATGCCTTCAGACGTGCAAAGTGCTATTGAAGCGCAAAACGTGC
AGGTTACTGCCGGGAAAATAGGGGCATTGCCTTCACCGAATACTCAGCAACTGACCGCAACGGTACGTGCGCAGTCTCGC
TTGCAGACGGTGGATCAGTTCAAAAATATTATCGTGAAAAGCCAGTCAGACGGCGCAGTTGTTCGTATAAAAGATGTGGC
TCGCGTTGAGATGGGCAGTGAAGATTATACCGCTATCGGCAAACTTAACGGTCACCCGTCTGCCGGGGTTGCTGTAATGC
TTTCGCCCGGTGCGAATGCGCTGAATACGGCGACGCTGGTCAAGGATAAGATTGCCGAATTCCAGCGGAACATGCCGCAG
GGATACGACATCGCATACCCGAAAGACAGCACTGAATTTATTAAAATCTCCGTAGAGGACGTAATTCAGACGCTGTTTGA
AGCCATCGTATTGGTGGTTTGCGTGATGTATTTATTCCTGCAAAACCTGCGTGCCACACTGATTCCGGCGTTAGCTGTCC
CCGTCGTTTTGCTGGGCACATTCGGCGTTCTTGCGTTGTTTGGCTATTCGATTAATACCCTGACGTTGTTTGCAATGGTG
CTGGCGATCGGCTTGCTGGTGGACGATGCCATTGTGGTGGTAGAGAACGTCGAACGCATTATGCGTGACGAAGGGTTGCC
CGCGCGTGAAGCCACGGAAAAATCAATGGGCGAGATTTCTGGCGCACTGGTTGCCATTGCGCTGGTGTTGTCAGCCGTAT
TCCTGCCGATGGCCTTCTTTGGGGGATCTACGGGCGTAATTTATCGTCAGTTCTCCATCACCATCATCTCCGCAATGCTG
CTTTCCGTGGTGGTGGCATTGACCTTGACTCCCGCCCTGTGCGGTTCCGTCCTCCAGCATGTTCCGCCACATAAAAAAGG
CTTTTTCGGCGCATTTAACCGCTTTTACCGCCGTACTGAAGATAAATATCAGCGAGGCGTAATTTATGTCCTGCGCCGTG
CAGCCCGAACGATGGGGCTTTATGTCGTGCTGGGTGGTGGAATGGCCCTGATGATGTGGAAACTGCCCGGCAGTTTCTTA
CCCACTGAAGACCAGGGCGAAATCATGGTGCAGTACACGCTGCCGGCCGGGGCGACCGCTGCCCGTACAGCAGAAGTGAA
TCGCCAGATTGTTGACTGGTTCCTGATTAACGAGAAAGCAAATACCGATGTCATCTTTACCGTTGATGGTTTCAGTTTTA
GCGGCAGCGGACAGAACACCGGGATGGCGTTTGTTTCGTTGAAAAACTGGTCTCAACGTAAAGGGGCAGAAAACACCGCC
CAGGCTATCGCCCTACGGGCAACCAAAGAGCTGGGCACAATTCGTGATGCGACGGTATTTGCGATGACGCCGCCAGCCGT
TGATGGGCTGGGGCAAAGCAATGGTTTTACGTTTGAATTGTTAGCTAACGGTGGAACCGATCGTGAAACACTGCTGCAAA
TGCGTAATCAGTTGATAGAAAAAGCGAATCAAAGTCCGGAGTTACATTCTGTACGCGCCAATGATTTGCCACAAATGCCG
CAATTGCAGGTAGATATTGATAGCAATAAAGCGGTGTCATTAGGGTTGAGTTTGAATGATGTCACCGACACCCTGTCCAG
TGCGTGGGGCGGTACTTATGTGAATGACTTTATTGACCGTGGTCGTGTGAAAAAAGTCTACATTCAGGGCGACAGCGAAT
TTCGTTCCGCGCCGTCAGACTTAGGTAAATGGTTTGTGCGCGGTAGCGATAACGCTATGACACCATTCTCTGCTTTTGCG
ACCACCCGCTGGCTGTATGGACCGGAAAGACTGGTGCGCTACAACGGCTCGGCAGCCTATGAAATTCAGGGCGAAAACGC
GACTGGCTTTAGTTCCGGCGATGCAATGACAAAAATGGAGGAACTGGCAAACAGTCTTCCTGCGGGAACAACCTGGGCCT
GGAGTGGTTTGTCATTGCAGGAGAAACTGGCCAGCGGTCAGGCATTAAGTCTGTATGCAGTTTCTATTCTGGTGGTTTTC
CTCTGCCTTGCAGCACTGTACGAAAGCTGGTCAGTCCCGTTCTCGGTCATTCTGGTGATCCCTCTGGGGCTTCTTGGCGC
GGCGCTGGCGGCCTGGATGCGTGATTTAAACAACGACGTTTACTTCCAGGTAGCGCTATTAACTACTATCGGCTTGTCAT
CGAAAAACGCCATTCTGATTGTGGAATTTGCTGAAGCGGCGGTTGCAGAGGGCTATTCCTTGAGTCGTGCGGCATTACGC
GCGGCGCAGACTCGTTTACGCCCAATCATCATGACCTCGCTGGCGTTTATTGCGGGGGTAATGCCGCTGGCGATAGCAAC
TGGCGCAGGGGCGAACAGCCGCATCGCCATTGGTACGGGCATTATTGGCGGCACGCTGACCGCTACATTACTGGCCATTT
TCTTCGTTCCTCTGTTTTTTGTACTGGTGAAACGTTTGTTTGCCGGTAAACCGCGCCGTCAGGAGTAA

Upstream 100 bases:

>100_bases
TGCACAACGGCGACCGACTGATTGTTGAAGGTTCTGCCAAAGTCACTTCAGGGCAGACCGTCAAGGCTGTTGAAGTTCAG
GCTAATGGAGGCAACGCCTG

Downstream 100 bases:

>100_bases
GTTATGTTGCGTCGTTCTCTTATTTTTCTGGTGTTGTTGAGTGCGGGATGTGTCTCGCTCGATCCTCACTACAGTACGCC
TGAATCCCCAATCCCGGCGA

Product: multidrug efflux transport protein EefB

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Multidrug-efflux transporter MexB [H]

Number of amino acids: Translated: 1035; Mature: 1035

Protein sequence:

>1035_residues
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFS
STSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQLTATVRAQSR
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQ
GYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMV
LAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRAARTMGLYVVLGGGMALMMWKLPGSFL
PTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTA
QAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSAFA
TTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVF
LCLAALYESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGKPRRQE

Sequences:

>Translated_1035_residues
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFS
STSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQLTATVRAQSR
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQ
GYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMV
LAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRAARTMGLYVVLGGGMALMMWKLPGSFL
PTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTA
QAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSAFA
TTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVF
LCLAALYESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGKPRRQE
>Mature_1035_residues
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFS
STSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQLTATVRAQSR
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQ
GYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMV
LAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRAARTMGLYVVLGGGMALMMWKLPGSFL
PTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTA
QAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSAFA
TTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVF
LCLAALYESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGKPRRQE

Specific function: The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP), showing that an energized inner membrane is required for efflux. It is thought that the MexB

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1786667, Length=1017, Percent_Identity=56.9321533923304, Blast_Score=1189, Evalue=0.0,
Organism=Escherichia coli, GI1789666, Length=1033, Percent_Identity=56.5343659244918, Blast_Score=1173, Evalue=0.0,
Organism=Escherichia coli, GI1788814, Length=1036, Percent_Identity=55.4054054054054, Blast_Score=1167, Evalue=0.0,
Organism=Escherichia coli, GI1789930, Length=1032, Percent_Identity=54.6511627906977, Blast_Score=1111, Evalue=0.0,
Organism=Escherichia coli, GI1788390, Length=1035, Percent_Identity=29.7584541062802, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1788391, Length=1049, Percent_Identity=30.2192564346997, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1786788, Length=1049, Percent_Identity=24.1182078169685, Blast_Score=236, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 111639; Mature: 111639

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLEN
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHH
SVTQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLP
HHHHHHHHHHCCCHHEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
SEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLVSNVQDPLARVEGVGSLQVFG
HHHHHCCCEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC
AEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQLTATVRAQSR
CCEEEEEEECHHHHHHCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANA
HHHHHHHHHHEEECCCCCCEEEEECHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCC
LNTATLVKDKIAEFQRNMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAIVVVENVERI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRDEGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRAARTMGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
YVVLGGGMALMMWKLPGSFLPTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKA
EEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEEEECCCC
NTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTAQAIALRATKELGTIRDATVF
CCCEEEEEECCEECCCCCCCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHHCCCCCCEEE
AMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
EECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCC
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSD
CEEEEECCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCHHHHCCHHH
LGKWFVRGSDNAMTPFSAFATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKME
HHHHEEECCCCCCCCHHHHHHHHHCCCCHHHEEECCCEEEEEECCCCCCCCCCHHHHHHH
ELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVILVI
HHHHHCCCCCCEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
PLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEEEHHHHHHCCCHHHHHHHH
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VLVKRLFAGKPRRQE
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLEN
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHH
SVTQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLP
HHHHHHHHHHCCCHHEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
SEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLVSNVQDPLARVEGVGSLQVFG
HHHHHCCCEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC
AEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQLTATVRAQSR
CCEEEEEEECHHHHHHCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
LQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANA
HHHHHHHHHHEEECCCCCCEEEEECHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCC
LNTATLVKDKIAEFQRNMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAIVVVENVERI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRDEGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAML
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
LSVVVALTLTPALCGSVLQHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRAARTMGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
YVVLGGGMALMMWKLPGSFLPTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINEKA
EEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEEEECCCC
NTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTAQAIALRATKELGTIRDATVF
CCCEEEEEECCEECCCCCCCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHHCCCCCCEEE
AMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMP
EECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCC
QLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSD
CEEEEECCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCHHHHCCHHH
LGKWFVRGSDNAMTPFSAFATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKME
HHHHEEECCCCCCCCHHHHHHHHHCCCCHHHEEECCCEEEEEECCCCCCCCCCHHHHHHH
ELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVILVI
HHHHHCCCCCCEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
PLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALR
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEEEHHHHHHCCCHHHHHHHH
AAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VLVKRLFAGKPRRQE
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7968531; 10984043; 9989496; 8226684; 8540696; 9603892; 10187844 [H]