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The map label for this gene is fanD [H]

Identifier: 170681449

GI number: 170681449

Start: 4000504

End: 4002861

Strand: Reverse

Name: fanD [H]

Synonym: EcSMS35_3926

Alternate gene names: 170681449

Gene position: 4002861-4000504 (Counterclockwise)

Preceding gene: 170680375

Following gene: 170679645

Centisome position: 78.98

GC content: 38.85

Gene sequence:

>2358_bases
ATGAAAAAAGAAATATTTATTGCCGCTATTATTTTTCATTTACTATCTAAAGGTGCTCTTGCCGAAGAGTTCAACTACAG
CTTTATTCGTGGAGGGAGTAAGGATATTCCTGATGTTTTAAACAGCAATAAAGAAAACGTACCGGGTAAATATGTTGTTG
ATGTTGTTTTCAATGGTTCTAAAATCGCGTCATCTACTGAGATGAGCATCGCAAAAGAGGATGCTGAGGGGATATGTCTT
TCTGATGAATGGCTAACTGAAAACGGCATTATAATTAATAAAGATTTTTATAAAAATGTTTATAATTCTGCACGCCAGTG
CTATTTGCTGGGTAATGAGGCGAACAGTAAAGTCGCGTTTGATCAATCGTTGCAAGAAGTATCTATTGATTTGCCACAGG
CAGGCTTCCAGGACGCAGCAAAAGATGGTGGTGTGTGGGACTATGGTAGTAACGGTTTTAAAATAGCTTATGACGTTAAT
ACTGCAAAAAATAGCAACCAGGAAAGAACCACCTACAGTAGTATTGATGGCCAGGTGAATCTGGGCGAATGGGTGTTATT
GGGTAGGGGGTATGCTTACCAGGGCGAAAATTTCGATACTAATAACCTGTTACTGACGCGGGCAATCAAATCACTGAAAT
CCGATTTGCAACTGGGCAAGACACAGCTTTATAACTCATTGAATAATGGTTTTACCTTTTACGGTGCTCAGCTTAAATCG
AATCAGGATATGTATCCGTGGAACTCTCGTGCCTATTCGCCGGTAATTAATGGTATTGCGCGAACCCATGCCAGGGTAAC
CATTGAGCAGAGTGGTTATACCTTAAAATCTATTGTCGTGCCTCCGGGACCATTTGTGATCAACGATCTTAACGGCGTTT
ACTCTGGCGATTTGATCATGAAAATCTATGAAGAGGATGGCTCCGTTCGTGAACAGCGTTTCCCTGTCGCAGTGTTGCCT
AATTTGTTAAGACCGGGAACGTATAACTACGCCCTCGCCATGGGTAGCAAAGTTAACCAAGATAATGGCGAACGGGATAA
AGAAAGTCTGTTTGCCCAAATGAGTTATGACTATGGATTCGAGCCTTTTACACTCAATAGCTCTTTATTGCTGGATAAAA
ATTATAACAATATTGGTTTAGGACTAATTCGCTCGTTTGGATGGTTTGGAGCCATGTCTTTTAGTGGCAACTTATCACAA
GCAAAATACCATAATGGTAAGAATCTAAAAGGCTATAGCACGTCATTAAAATATGCAAAAGCGCTTGGTGATAATGCAAA
TTTACAGCTTATTGGTTACCGTTTTAATTCAGAGGATTATATTGACTATGCTGATTTTACTTATAATTCATATAGTTTTA
TAAGAAATAGGCCAAAGCAACGCTATGAGTCAATCGTTACCTACCAGCTACCAGAAAAAGGTATGTTTTTAAACTTTTCT
GCGTGGAAGGAAGATTACTGGGATAATTATAACGAGGTCGGTGCTAACTTAAGTCTGACAAAAAGTTTTGATCAAATAAC
AATGACACTGAACGGTGGTTATTCCAGACTGCAAAATATGGATGCTGACTATAATGTTGGTTTGTCATTAAGTGTGCCGT
TAAGTCTGTTTGATAAAACACATTATAGTTTTTCGAATGTTAACTATGATCGACGTACGGGGACCAGTATGAATACTGGG
ATCTCAGGAATGATTAATCAAAGGCTGAGTTATAACGCATCAGTTAACCAGACGCGTGATACTATCGGTGGTACACTTTC
TGCCTCCTATTTATTCGACTGGATGCAGACGTCAGCAACGTATTCACAAACTGGGAAAAATTCATCTACTTCACTCCAGT
TGGGTGGTAGTGTAATTGGTGTGCCAGAAGGTGGCATAATATTTACTCCAGTTAAAAATGATCAACTGGCTATCGTGCAA
ATGAAAGATGTCCCCGGTGTTATGTTTAACGGTTCTTTACCGGGAGATAAATATGGTCGGGCGGTAATCCCACTTACTGC
TTATAACAATAATACGATTTCTGTAAATGCAGAAAAATTACCGAAGAATATTGAGCTTACAGATAATGCGATTAATGTGA
CCCCAACGGGAAATGCTATCATTTATAAAAATGTGAAGTTTAAGAAAATTAATACCTATGTGGTTAAACTTTATGGGAAA
AATGGTTATGTCGTTCCTATGGGTAGCATCGCAAAAAATACACAGGGTAAAGAAGTGGGTTATGTAAATAACGGTGGTAT
TTTGCTGATGAACCTTGAAACACACGATGAAGGTGTTATTTCGCTTGACCAGTGTCAATTTAATACGCAGTCACTGAAGA
AAAACTATGACCAAACTCAGGAGATTCACTGTGAGTAA

Upstream 100 bases:

>100_bases
CAGCAAGTTATGTTGTTGCTTATAAATAATATATGAGCGAAGGAAGGGAGGATTAATCTCCTCCCTTCTTATTACCTGAT
GTTTATGGCAAGGGAAAATA

Downstream 100 bases:

>100_bases
CAATGTAATGAAAAAAATAAATCTCATGCCAGTATTGGCTTTGCTGCTGATCTGCTTTAATAGCCATGCTGCCTTTGTTC
TCAATAGTACGCGTTATATT

Product: putative fimbrial usher protein FanD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MKKEIFIAAIIFHLLSKGALAEEFNYSFIRGGSKDIPDVLNSNKENVPGKYVVDVVFNGSKIASSTEMSIAKEDAEGICL
SDEWLTENGIIINKDFYKNVYNSARQCYLLGNEANSKVAFDQSLQEVSIDLPQAGFQDAAKDGGVWDYGSNGFKIAYDVN
TAKNSNQERTTYSSIDGQVNLGEWVLLGRGYAYQGENFDTNNLLLTRAIKSLKSDLQLGKTQLYNSLNNGFTFYGAQLKS
NQDMYPWNSRAYSPVINGIARTHARVTIEQSGYTLKSIVVPPGPFVINDLNGVYSGDLIMKIYEEDGSVREQRFPVAVLP
NLLRPGTYNYALAMGSKVNQDNGERDKESLFAQMSYDYGFEPFTLNSSLLLDKNYNNIGLGLIRSFGWFGAMSFSGNLSQ
AKYHNGKNLKGYSTSLKYAKALGDNANLQLIGYRFNSEDYIDYADFTYNSYSFIRNRPKQRYESIVTYQLPEKGMFLNFS
AWKEDYWDNYNEVGANLSLTKSFDQITMTLNGGYSRLQNMDADYNVGLSLSVPLSLFDKTHYSFSNVNYDRRTGTSMNTG
ISGMINQRLSYNASVNQTRDTIGGTLSASYLFDWMQTSATYSQTGKNSSTSLQLGGSVIGVPEGGIIFTPVKNDQLAIVQ
MKDVPGVMFNGSLPGDKYGRAVIPLTAYNNNTISVNAEKLPKNIELTDNAINVTPTGNAIIYKNVKFKKINTYVVKLYGK
NGYVVPMGSIAKNTQGKEVGYVNNGGILLMNLETHDEGVISLDQCQFNTQSLKKNYDQTQEIHCE

Sequences:

>Translated_785_residues
MKKEIFIAAIIFHLLSKGALAEEFNYSFIRGGSKDIPDVLNSNKENVPGKYVVDVVFNGSKIASSTEMSIAKEDAEGICL
SDEWLTENGIIINKDFYKNVYNSARQCYLLGNEANSKVAFDQSLQEVSIDLPQAGFQDAAKDGGVWDYGSNGFKIAYDVN
TAKNSNQERTTYSSIDGQVNLGEWVLLGRGYAYQGENFDTNNLLLTRAIKSLKSDLQLGKTQLYNSLNNGFTFYGAQLKS
NQDMYPWNSRAYSPVINGIARTHARVTIEQSGYTLKSIVVPPGPFVINDLNGVYSGDLIMKIYEEDGSVREQRFPVAVLP
NLLRPGTYNYALAMGSKVNQDNGERDKESLFAQMSYDYGFEPFTLNSSLLLDKNYNNIGLGLIRSFGWFGAMSFSGNLSQ
AKYHNGKNLKGYSTSLKYAKALGDNANLQLIGYRFNSEDYIDYADFTYNSYSFIRNRPKQRYESIVTYQLPEKGMFLNFS
AWKEDYWDNYNEVGANLSLTKSFDQITMTLNGGYSRLQNMDADYNVGLSLSVPLSLFDKTHYSFSNVNYDRRTGTSMNTG
ISGMINQRLSYNASVNQTRDTIGGTLSASYLFDWMQTSATYSQTGKNSSTSLQLGGSVIGVPEGGIIFTPVKNDQLAIVQ
MKDVPGVMFNGSLPGDKYGRAVIPLTAYNNNTISVNAEKLPKNIELTDNAINVTPTGNAIIYKNVKFKKINTYVVKLYGK
NGYVVPMGSIAKNTQGKEVGYVNNGGILLMNLETHDEGVISLDQCQFNTQSLKKNYDQTQEIHCE
>Mature_785_residues
MKKEIFIAAIIFHLLSKGALAEEFNYSFIRGGSKDIPDVLNSNKENVPGKYVVDVVFNGSKIASSTEMSIAKEDAEGICL
SDEWLTENGIIINKDFYKNVYNSARQCYLLGNEANSKVAFDQSLQEVSIDLPQAGFQDAAKDGGVWDYGSNGFKIAYDVN
TAKNSNQERTTYSSIDGQVNLGEWVLLGRGYAYQGENFDTNNLLLTRAIKSLKSDLQLGKTQLYNSLNNGFTFYGAQLKS
NQDMYPWNSRAYSPVINGIARTHARVTIEQSGYTLKSIVVPPGPFVINDLNGVYSGDLIMKIYEEDGSVREQRFPVAVLP
NLLRPGTYNYALAMGSKVNQDNGERDKESLFAQMSYDYGFEPFTLNSSLLLDKNYNNIGLGLIRSFGWFGAMSFSGNLSQ
AKYHNGKNLKGYSTSLKYAKALGDNANLQLIGYRFNSEDYIDYADFTYNSYSFIRNRPKQRYESIVTYQLPEKGMFLNFS
AWKEDYWDNYNEVGANLSLTKSFDQITMTLNGGYSRLQNMDADYNVGLSLSVPLSLFDKTHYSFSNVNYDRRTGTSMNTG
ISGMINQRLSYNASVNQTRDTIGGTLSASYLFDWMQTSATYSQTGKNSSTSLQLGGSVIGVPEGGIIFTPVKNDQLAIVQ
MKDVPGVMFNGSLPGDKYGRAVIPLTAYNNNTISVNAEKLPKNIELTDNAINVTPTGNAIIYKNVKFKKINTYVVKLYGK
NGYVVPMGSIAKNTQGKEVGYVNNGGILLMNLETHDEGVISLDQCQFNTQSLKKNYDQTQEIHCE

Specific function: Involved in the export and assembly of K99 fimbrial subunits across the outer membrane [H]

COG id: COG3188

COG function: function code NU; P pilus assembly protein, porin PapC

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial export usher family [H]

Homologues:

Organism=Escherichia coli, GI1789533, Length=772, Percent_Identity=28.6269430051813, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI87081778, Length=776, Percent_Identity=24.6134020618557, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI1788427, Length=841, Percent_Identity=24.9702734839477, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI1786332, Length=807, Percent_Identity=25.7744733581165, Blast_Score=190, Evalue=4e-49,
Organism=Escherichia coli, GI1787172, Length=846, Percent_Identity=25.886524822695, Blast_Score=186, Evalue=7e-48,
Organism=Escherichia coli, GI1790772, Length=798, Percent_Identity=25.6892230576441, Blast_Score=175, Evalue=9e-45,
Organism=Escherichia coli, GI1786744, Length=774, Percent_Identity=24.8062015503876, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI1789610, Length=785, Percent_Identity=22.6751592356688, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000015
- InterPro:   IPR018030 [H]

Pfam domain/function: PF00577 Usher [H]

EC number: NA

Molecular weight: Translated: 87347; Mature: 87347

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS01151 FIMBRIAL_USHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEIFIAAIIFHLLSKGALAEEFNYSFIRGGSKDIPDVLNSNKENVPGKYVVDVVFNGS
CCCCEEHHHHHHHHHCCCCCHHHCCCCEECCCCCCCCHHHCCCCCCCCCEEEEEEEECCC
KIASSTEMSIAKEDAEGICLSDEWLTENGIIINKDFYKNVYNSARQCYLLGNEANSKVAF
EECCCCHHEEECCCCCCEEECCCEECCCCEEECHHHHHHHHCCCEEEEEECCCCCCEEEH
DQSLQEVSIDLPQAGFQDAAKDGGVWDYGSNGFKIAYDVNTAKNSNQERTTYSSIDGQVN
HHCHHHHEECCCCCCCHHHHCCCCEEECCCCCEEEEEEECCCCCCCCCCCCHHCCCCCEE
LGEWVLLGRGYAYQGENFDTNNLLLTRAIKSLKSDLQLGKTQLYNSLNNGFTFYGAQLKS
CCCEEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECC
NQDMYPWNSRAYSPVINGIARTHARVTIEQSGYTLKSIVVPPGPFVINDLNGVYSGDLIM
CCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCEEEEEEECCCCEEEECCCCCCCCCEEE
KIYEEDGSVREQRFPVAVLPNLLRPGTYNYALAMGSKVNQDNGERDKESLFAQMSYDYGF
EEEECCCCHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
EPFTLNSSLLLDKNYNNIGLGLIRSFGWFGAMSFSGNLSQAKYHNGKNLKGYSTSLKYAK
CEEEECCEEEEECCCCCCHHHHHHHCCCCEEEECCCCCCHHEECCCCCCCCCCHHHHHHH
ALGDNANLQLIGYRFNSEDYIDYADFTYNSYSFIRNRPKQRYESIVTYQLPEKGMFLNFS
HCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHHHCCHHHHHHCEEEEECCCCCEEEEEH
AWKEDYWDNYNEVGANLSLTKSFDQITMTLNGGYSRLQNMDADYNVGLSLSVPLSLFDKT
HHHHHHCCCHHHHCCCEEEEECCEEEEEEECCCHHHHHCCCCCCCCCEEEECCHHHHCCC
HYSFSNVNYDRRTGTSMNTGISGMINQRLSYNASVNQTRDTIGGTLSASYLFDWMQTSAT
CCEECCCCCCCCCCCCCCCCCHHHHHCCEECCCCCCCHHHHCCCCEEHHHHHHHHHHCCH
YSQTGKNSSTSLQLGGSVIGVPEGGIIFTPVKNDQLAIVQMKDVPGVMFNGSLPGDKYGR
HHHCCCCCCCEEEECCEEEECCCCCEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCC
AVIPLTAYNNNTISVNAEKLPKNIELTDNAINVTPTGNAIIYKNVKFKKINTYVVKLYGK
EEEEEEEECCCEEEEEHHHCCCCEEEECCEEEECCCCCEEEEECEEEEEEEEEEEEEECC
NGYVVPMGSIAKNTQGKEVGYVNNGGILLMNLETHDEGVISLDQCQFNTQSLKKNYDQTQ
CCEEEECCHHHCCCCCCEEEEEECCCEEEEEEECCCCCCEEEHHCCCCHHHHHHCCCCCC
EIHCE
EECCC
>Mature Secondary Structure
MKKEIFIAAIIFHLLSKGALAEEFNYSFIRGGSKDIPDVLNSNKENVPGKYVVDVVFNGS
CCCCEEHHHHHHHHHCCCCCHHHCCCCEECCCCCCCCHHHCCCCCCCCCEEEEEEEECCC
KIASSTEMSIAKEDAEGICLSDEWLTENGIIINKDFYKNVYNSARQCYLLGNEANSKVAF
EECCCCHHEEECCCCCCEEECCCEECCCCEEECHHHHHHHHCCCEEEEEECCCCCCEEEH
DQSLQEVSIDLPQAGFQDAAKDGGVWDYGSNGFKIAYDVNTAKNSNQERTTYSSIDGQVN
HHCHHHHEECCCCCCCHHHHCCCCEEECCCCCEEEEEEECCCCCCCCCCCCHHCCCCCEE
LGEWVLLGRGYAYQGENFDTNNLLLTRAIKSLKSDLQLGKTQLYNSLNNGFTFYGAQLKS
CCCEEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECC
NQDMYPWNSRAYSPVINGIARTHARVTIEQSGYTLKSIVVPPGPFVINDLNGVYSGDLIM
CCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCEEEEEEECCCCEEEECCCCCCCCCEEE
KIYEEDGSVREQRFPVAVLPNLLRPGTYNYALAMGSKVNQDNGERDKESLFAQMSYDYGF
EEEECCCCHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
EPFTLNSSLLLDKNYNNIGLGLIRSFGWFGAMSFSGNLSQAKYHNGKNLKGYSTSLKYAK
CEEEECCEEEEECCCCCCHHHHHHHCCCCEEEECCCCCCHHEECCCCCCCCCCHHHHHHH
ALGDNANLQLIGYRFNSEDYIDYADFTYNSYSFIRNRPKQRYESIVTYQLPEKGMFLNFS
HCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHHHCCHHHHHHCEEEEECCCCCEEEEEH
AWKEDYWDNYNEVGANLSLTKSFDQITMTLNGGYSRLQNMDADYNVGLSLSVPLSLFDKT
HHHHHHCCCHHHHCCCEEEEECCEEEEEEECCCHHHHHCCCCCCCCCEEEECCHHHHCCC
HYSFSNVNYDRRTGTSMNTGISGMINQRLSYNASVNQTRDTIGGTLSASYLFDWMQTSAT
CCEECCCCCCCCCCCCCCCCCHHHHHCCEECCCCCCCHHHHCCCCEEHHHHHHHHHHCCH
YSQTGKNSSTSLQLGGSVIGVPEGGIIFTPVKNDQLAIVQMKDVPGVMFNGSLPGDKYGR
HHHCCCCCCCEEEECCEEEECCCCCEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCC
AVIPLTAYNNNTISVNAEKLPKNIELTDNAINVTPTGNAIIYKNVKFKKINTYVVKLYGK
EEEEEEEECCCEEEEEHHHCCCCEEEECCEEEECCCCCEEEEECEEEEEEEEEEEEEECC
NGYVVPMGSIAKNTQGKEVGYVNNGGILLMNLETHDEGVISLDQCQFNTQSLKKNYDQTQ
CCEEEECCHHHCCCCCCEEEEEECCCEEEEEEECCCCCCEEEHHCCCCHHHHHHCCCCCC
EIHCE
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2564179; 1713284 [H]