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The map label for this gene is xylB [H]

Identifier: 170680828

GI number: 170680828

Start: 3954075

End: 3955529

Strand: Reverse

Name: xylB [H]

Synonym: EcSMS35_3887

Alternate gene names: 170680828

Gene position: 3955529-3954075 (Counterclockwise)

Preceding gene: 170681343

Following gene: 170680413

Centisome position: 78.04

GC content: 53.61

Gene sequence:

>1455_bases
ATGTATATCGGGATAGATCTTGGCACCTCGGGCGTAAAAGTTATTTTGCTCAATGAGCAGGGTGAGGTGGTTGCTGCGCA
AACGGAAAAGCTGACCGTTTCGCGCCCGCATCCACTCTGGTCGGAACAAGACCCGGAACAGTGGTGGCAGGCAACTGATC
GCGCAATGAAAGCTCTGGGCGTTCAGCATTCTCTGCAAGACGTTAAAGCATTAGGTATTGCCGGACAGATGCACGGTGCA
ACCTTACTGGATGCCCAGCAACGGGTATTACGCCCTGCCATTTTGTGGAACGACGGGCGCTGTGCGCAAGAGTGCACTTT
GCTGGAAGCGCGAGTTCCGCAATCACGGGTGATTACCGGTAACCTGATGATGCCCGGATTTACTGCGCCTAAATTGCTAT
GGGTTCATCGGCATGAGCCGGAGATATTCCGTCAAATCGATAAAGTATTATTACCGAAAGATTACTTGCGTCTGCGTATG
ACGGGGGAGTTTGCCAGCGATATGTCTGACGCAGCTGGCACTATGTGGCTGGATGTCGCAAAGCGTGACTGGAGCGATCT
CATGCTGCAGGCTTGCCACTTATCTCGTGACCAGATGCCCGCATTATACGAAGGCAGCGAAATTACTGGTGCTTTGCTAC
CTGAAGTTGCGAAAGCGTGGGGTATGGCGACGGTGCCAGTTGTCGCAGGCGGTGGCGATAATGCAGCTGGTGCGGTTGGT
GTGGGAATGGTTGATGCTAATCAGGCAATGTTATCGCTGGGGACGTCGGGGGTCTATTTTGCTGTCAGCGAAGGATTCTT
AAGCAAGCCAGAAAGCGCCGTACACAGCTTTTGCCATGCGCTCCCGCAGCGTTGGCATTTAATGTCTGTGATGCTGAGTG
CGGCTTCTTGCCTGGATTGGGCCGCAAAATTAACCGGTCTGAGCAATGTTCCAGCTTTAATCGCGGCTGCTCAACAGGCT
GATGAAAGTACCGAGCCTGTCTGGTTTCTGCCTTATCTTTCCGGTGAACGTACGCCACACAACAATCCCCAGGCGAAGGG
GGTTTTCTTTGGTTTGACCCATCAACATGGTGCTAATGAACTGGCGCGAGCAGTGCTGGAAGGCGTGGGTTATGCGCTGG
CAGATGGCATGGATGTCGTACATGCCTGCGGCATTAAACCGCAAAGTGTTACGCTGATTGGTGGCGGGGCTCGTAGTGAG
TACTGGCGTCAGATGCTGGCGGATATCAGCGGTCAGCAGCTCGATTACCGCACAGGGGGAGATGTGGGGCCAGCACTGGG
TGCAGCAAGGCTGGCGCAGATTGCGACGAATCCAGAGAAATCGCTCATTGAATTGTTGCCACAACTACCGTTAGAACAGT
CGCATCTACCAGATGCGCAGCGTTATGCCGCTTATCAGCCACGACGAGAAACGTTCCGTCGCCTCTATCAGCAACTTCTG
CCATTAATGGCGTAA

Upstream 100 bases:

>100_bases
TGGTAAATCATTATCTGTTCGACAAATAACGGCTAACTGTGCAGTCCGTTGGCCCGGTTATCAGTAGCGATACCGGGCAT
TTTTTTAAGGAACGATCGAT

Downstream 100 bases:

>100_bases
ACGTTATCCCCTGCCTGACCGGGTGGGGGATAATTCACATCTATATATCTCAGTAATTAATTAATATTTAGTATGAATTT
ATTCTGAAAATCATTTGTTA

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVHRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQA
DESTEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGANELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIATNPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA

Sequences:

>Translated_484_residues
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVHRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQA
DESTEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGANELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIATNPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA
>Mature_484_residues
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVHRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQA
DESTEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGANELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIATNPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=437, Percent_Identity=22.4256292906178, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI189409120, Length=436, Percent_Identity=22.4770642201835, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4504007, Length=436, Percent_Identity=22.4770642201835, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI41393575, Length=431, Percent_Identity=22.2737819025522, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI164663828, Length=534, Percent_Identity=23.0337078651685, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI18860918, Length=335, Percent_Identity=26.2686567164179, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789987, Length=484, Percent_Identity=98.5537190082645, Blast_Score=975, Evalue=0.0,
Organism=Escherichia coli, GI1790361, Length=486, Percent_Identity=23.8683127572016, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790005, Length=492, Percent_Identity=24.1869918699187, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787789, Length=510, Percent_Identity=24.3137254901961, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789168, Length=421, Percent_Identity=25.6532066508314, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=442, Percent_Identity=23.9819004524887, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17864214, Length=468, Percent_Identity=23.2905982905983, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24655555, Length=459, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655560, Length=459, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655570, Length=459, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655574, Length=459, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655565, Length=459, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24654573, Length=411, Percent_Identity=23.6009732360097, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356607, Length=318, Percent_Identity=23.8993710691824, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52682; Mature: 52682

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALG
CEEEEEECCCCEEEEEECCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
VQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHCCCCCEEEEC
NLMMPGFTAPKLLWVHRHEPEIFRQIDKVLLPKDYLRLRMTGEFASDMSDAAGTMWLDVA
CEECCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHCCCEEEHHH
KRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
HCCHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDW
EEEECCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAKLTGLSNVPALIAAAQQADESTEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGANE
HHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSEYWRQMLADISGQQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEECCCCC
DVGPALGAARLAQIATNPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
PLMA
HHCC
>Mature Secondary Structure
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALG
CEEEEEECCCCEEEEEECCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
VQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHCCCCCEEEEC
NLMMPGFTAPKLLWVHRHEPEIFRQIDKVLLPKDYLRLRMTGEFASDMSDAAGTMWLDVA
CEECCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHCCCEEEHHH
KRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
HCCHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDW
EEEECCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAKLTGLSNVPALIAAAQQADESTEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGANE
HHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSEYWRQMLADISGQQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEECCCCC
DVGPALGAARLAQIATNPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
PLMA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]