Click here to switch to the map view.

The map label for this gene is ispG

Identifier: 170077366

GI number: 170077366

Start: 772046

End: 773266

Strand: Reverse

Name: ispG

Synonym: SYNPCC7002_A0743

Alternate gene names: 170077366

Gene position: 773266-772046 (Counterclockwise)

Preceding gene: 170077367

Following gene: 170077363

Centisome position: 25.71

GC content: 53.32

Gene sequence:

>1221_bases
ATGCAAGCTGTAGAGCGTCCTGTGCAAACGACCGATTCCCTTGTGGATACCACTATCCATCGCCGGAAAACCAGAGCTGT
CAAGGTGGGCAATGTCACCATCGGCAGTGATTATCCTGTGGTTGTCCAGTCGATGATCAACGAAGATACCCTTGACATAG
AGGGCTCCGTCGCGGCAATCCGCCGACTTCATGAAATTGGCTGTGAAATCGTCCGGGTAACTGTTCCGAGTATGGCCCAC
GCCCGTTCCCTGGCTCAGATCAAAGCGAAGCTCGCCGAGACCTACCAGGCAGTGCCAATTGTGGCGGATGTCCACCATAA
CGGCATGAAAATTGCTCTGGAAGTTGCCAAACACGTGGATAAAGTGCGCATCAATCCCGGTCTTTATGTTTTTGAACAGG
CCAGTGGCGATCGCACTGGTTATACCGAAGCAGAATTTGCGGCCATTGGTGAAAAGATTCGTGAAACCCTCGAACCCTTG
GTGGTTTCCCTGCGGGATCAAGGCAAAGCCATGCGCATCGGCGTCAACCATGGTTCCCTCGCCGAGCGAATGCTCTTCAC
CTACGGGGATACTCCCGAAGGCATGGTCGAATCAGCCCTAGAATTTATTCGGATTTGTCAGTCCCTCGATTTCCATAACC
TGATCATTTCCATGAAGGCATCCCGTGTTCCGGTGATGTTGGCCGCCTATCGCCTCATGGCTAAACGAATGGATGAACTC
GGCATGGATTATCCCCTCCACCTGGGCGTAACCGAAGCTGGAGATGGAGAATATGGCCGCATTAAATCTACCGCAGGCAT
TGGGACGCTCCTGGCGGAAGGCATTGGCGACACAATCCGTGTTTCCCTCACGGAAGCACCGGAAAAGGAAATTCCCGTCT
GCTATAGCATCCTCCAAGCCCTAGGCCTACGGAAAACCATGGTGGAATACGTCGCCTGCCCTTCCTGTGGCCGGACGCTT
TTTAACCTCGAAGAAGTGCTCCACAAGGTGCGCGAAGCGACAAATCACCTCACGGGTCTAGATATTGCCGTAATGGGTTG
TATCGTCAATGGCCCCGGTGAAATGGCCGATGCGGACTATGGCTATGTGGGGAAAACGCCCGGTGTAATTTCCCTATACC
GTGGTCGGGAAGAAATCCGCAAAGTCCCCGAAGCCCAAGGGGTTGAAGAACTGATTAACCTAATCAAAGCTGATGGTCGC
TGGGTTGATCCGCCCCAATAG

Upstream 100 bases:

>100_bases
TAGCCCAGATGCCCTTTCCCGTTGCCTAGAACCTTTGCCAACGCTTATGCTTAGATCCTAGATACCAGCGACTTTTTGTA
ATTTCCTATCCTCAAGTTCC

Downstream 100 bases:

>100_bases
TTTTTGACAGAAATTCTCTCAATCATTTGTCACCCAGGCGATATCAATTTATCCCCTGGGTTTTTTCTCGTATCCGATCA
ATAAACCGATTAATGCAGCA

Product: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

Products: NA

Alternate protein names: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MQAVERPVQTTDSLVDTTIHRRKTRAVKVGNVTIGSDYPVVVQSMINEDTLDIEGSVAAIRRLHEIGCEIVRVTVPSMAH
ARSLAQIKAKLAETYQAVPIVADVHHNGMKIALEVAKHVDKVRINPGLYVFEQASGDRTGYTEAEFAAIGEKIRETLEPL
VVSLRDQGKAMRIGVNHGSLAERMLFTYGDTPEGMVESALEFIRICQSLDFHNLIISMKASRVPVMLAAYRLMAKRMDEL
GMDYPLHLGVTEAGDGEYGRIKSTAGIGTLLAEGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTL
FNLEEVLHKVREATNHLTGLDIAVMGCIVNGPGEMADADYGYVGKTPGVISLYRGREEIRKVPEAQGVEELINLIKADGR
WVDPPQ

Sequences:

>Translated_406_residues
MQAVERPVQTTDSLVDTTIHRRKTRAVKVGNVTIGSDYPVVVQSMINEDTLDIEGSVAAIRRLHEIGCEIVRVTVPSMAH
ARSLAQIKAKLAETYQAVPIVADVHHNGMKIALEVAKHVDKVRINPGLYVFEQASGDRTGYTEAEFAAIGEKIRETLEPL
VVSLRDQGKAMRIGVNHGSLAERMLFTYGDTPEGMVESALEFIRICQSLDFHNLIISMKASRVPVMLAAYRLMAKRMDEL
GMDYPLHLGVTEAGDGEYGRIKSTAGIGTLLAEGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTL
FNLEEVLHKVREATNHLTGLDIAVMGCIVNGPGEMADADYGYVGKTPGVISLYRGREEIRKVPEAQGVEELINLIKADGR
WVDPPQ
>Mature_406_residues
MQAVERPVQTTDSLVDTTIHRRKTRAVKVGNVTIGSDYPVVVQSMINEDTLDIEGSVAAIRRLHEIGCEIVRVTVPSMAH
ARSLAQIKAKLAETYQAVPIVADVHHNGMKIALEVAKHVDKVRINPGLYVFEQASGDRTGYTEAEFAAIGEKIRETLEPL
VVSLRDQGKAMRIGVNHGSLAERMLFTYGDTPEGMVESALEFIRICQSLDFHNLIISMKASRVPVMLAAYRLMAKRMDEL
GMDYPLHLGVTEAGDGEYGRIKSTAGIGTLLAEGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTL
FNLEEVLHKVREATNHLTGLDIAVMGCIVNGPGEMADADYGYVGKTPGVISLYRGREEIRKVPEAQGVEELINLIKADGR
WVDPPQ

Specific function: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate

COG id: COG0821

COG function: function code I; Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispG family

Homologues:

Organism=Escherichia coli, GI1788863, Length=349, Percent_Identity=39.2550143266476, Blast_Score=234, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISPG_SYNP2 (B1XHZ7)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734004.1
- ProteinModelPortal:   B1XHZ7
- GeneID:   6057213
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A0743
- HOGENOM:   HBG335271
- OMA:   APIVVQS
- ProtClustDB:   PRK00366
- HAMAP:   MF_00159
- InterPro:   IPR016425
- InterPro:   IPR004588
- PIRSF:   PIRSF004640
- TIGRFAMs:   TIGR00612

Pfam domain/function: PF04551 GcpE

EC number: =1.17.7.1

Molecular weight: Translated: 44479; Mature: 44479

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVERPVQTTDSLVDTTIHRRKTRAVKVGNVTIGSDYPVVVQSMINEDTLDIEGSVAAI
CCCHHHHHHHHHHHHHHHHHHHHHCEEEECEEEECCCCHHHHHHHHCCCCCCCCCHHHHH
RRLHEIGCEIVRVTVPSMAHARSLAQIKAKLAETYQAVPIVADVHHNGMKIALEVAKHVD
HHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
KVRINPGLYVFEQASGDRTGYTEAEFAAIGEKIRETLEPLVVSLRDQGKAMRIGVNHGSL
HEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHH
AERMLFTYGDTPEGMVESALEFIRICQSLDFHNLIISMKASRVPVMLAAYRLMAKRMDEL
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHH
GMDYPLHLGVTEAGDGEYGRIKSTAGIGTLLAEGIGDTIRVSLTEAPEKEIPVCYSILQA
CCCCCEEECCEECCCCCCCCEECCCHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHH
LGLRKTMVEYVACPSCGRTLFNLEEVLHKVREATNHLTGLDIAVMGCIVNGPGEMADADY
HCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEECCCCCCCCCCC
GYVGKTPGVISLYRGREEIRKVPEAQGVEELINLIKADGRWVDPPQ
CCCCCCCCEEEHHCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQAVERPVQTTDSLVDTTIHRRKTRAVKVGNVTIGSDYPVVVQSMINEDTLDIEGSVAAI
CCCHHHHHHHHHHHHHHHHHHHHHCEEEECEEEECCCCHHHHHHHHCCCCCCCCCHHHHH
RRLHEIGCEIVRVTVPSMAHARSLAQIKAKLAETYQAVPIVADVHHNGMKIALEVAKHVD
HHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
KVRINPGLYVFEQASGDRTGYTEAEFAAIGEKIRETLEPLVVSLRDQGKAMRIGVNHGSL
HEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHH
AERMLFTYGDTPEGMVESALEFIRICQSLDFHNLIISMKASRVPVMLAAYRLMAKRMDEL
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHH
GMDYPLHLGVTEAGDGEYGRIKSTAGIGTLLAEGIGDTIRVSLTEAPEKEIPVCYSILQA
CCCCCEEECCEECCCCCCCCEECCCHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHH
LGLRKTMVEYVACPSCGRTLFNLEEVLHKVREATNHLTGLDIAVMGCIVNGPGEMADADY
HCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEECCCCCCCCCCC
GYVGKTPGVISLYRGREEIRKVPEAQGVEELINLIKADGRWVDPPQ
CCCCCCCCEEEHHCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA