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The map label for this gene is recG [H]

Identifier: 170026387

GI number: 170026387

Start: 4608496

End: 4610577

Strand: Direct

Name: recG [H]

Synonym: YPK_4180

Alternate gene names: 170026387

Gene position: 4608496-4610577 (Clockwise)

Preceding gene: 170026386

Following gene: 170026389

Centisome position: 98.27

GC content: 51.63

Gene sequence:

>2082_bases
ATGAAAGGCCGCCTACTGGACGCCGTACCCCTCAGTACACTTTCCGGAGTTGGCGCAAGTCAGGCTGGAAAACTCGCCAA
GATAGGTTTGGAAACCATTCAGGACCTGCTGCTGCACCTTCCGCTACGTTATGAGGATCGTACTCGTCTATATCGTATTG
GTGATCTGCTGCCCGGTCTTTCGGTCACGGTTGAAGGTGAAGTTCTACGCTCTGATATTAGCTTTGGTCGCCGCCGTATG
ATGACCTGTCAAATCAGCGATGGTAGCGGCGTTCTCACCCTGCGCTTTTTTAACTTCAATGCAGCAATGAAAAACAGTCT
GTCAGTAGGCAAACATGTCATTGCTTATGGCGAAGCCAAACGAGGCAATAACGGGCCAGAAATCATTCACCCTGAATATC
GGGTTCATGGCGAGAATATTGGCGTTGAATTACAGGAATCGCTGACACCAGTCTATCCCACGACCGAGGGCATTCGTCAG
GCAACTCTGCGCAAACTTATCGATCAGGCACTGGCAATGCTGGACACCTGTGTTATTGCTGAGTTACTGCCAATTGAATT
GAGCCGTTCTCTCATCAGCCTGCCTGAAGCGATTCATACTCTGCATCGCCCTCCGGCAGATATTCAATTAGCTGATTTAG
AACAAGGGAAGCACCCCGCTCAACGGCGTCTGATCATGGAAGAGTTGCTGGCTCATAACCTCAGTATGTTGGCAGTCAGG
GCGGGTGCACAAAGCTACCGAGCATTGCCATTAATGGCCGAAGAGCAGCTTAAACAACGTTTTCTGGCCGCCCTACCTTT
TACGCCTACTCAAGCCCAGCAACGGGTCGTCGCCGAAATTGAACGGGATATGACCCAAAGTTTCCCGATGATGCGACTGA
TTCAGGGGGATGTCGGTTCCGGTAAAACACTGGTAGCCGCACTGGCCGCGCTACGGGCCATCGCTCACGGTAAGCAGGTT
GCCCTGATGGCACCGACCGAACTGCTGGCAGAACAGCACGCCACTACTTTCCGTCAATGGCTGGAGCCTCTTGGGTTTAG
TGTCGGCTGGTTGGCTGGCAAGCAAAAGGGGAAAGCGCGGTTAGCACAACAAGAGGCCGTTGCCAGCGGTCAGGTCTCCA
TGGTGATCGGTACTCATGCCATGTTTCAAGAACAGGTGCAATTCTCGGGGTTAGCACTGGTAATTATTGATGAGCAGCAT
CGTTTCGGTGTTCACCAGCGCCTCACGTTATGGGAAAAAGGTGAGGAGCAAGGCTTCCATCCACATCAATTAATCATGAC
GGCAACCCCGATCCCAAGAACATTAGCCATGACTGCCTATGCAGATCTCGATACCTCCGTGATTGATGAATTACCGCCAG
GCAGAACCCCCGTGACAACGGTGGCAATCCCGGATACTCGCCGTAGTGATGTTATTCAGCGGGTTAAAAATGCGTGCCTG
GAAGAGGGTAGGCAAGCATATTGGGTATGTACCTTGATTGAAGAATCAGAGTTGCTGGAGGCTCAGGCTGCAGAGGTAAC
GTGCGAAGAGCTGAAAATTGCCTTACCGGAAATTAAAGTTGGCTTGGTTCATGGGCGGATGAAAGGCCCCGAAAAACAGG
CGATTATGCTGGCCTTTAAACAAGGTGAGCTACAGTTATTGGTCGCAACCACGGTGATTGAAGTGGGAGTTGATGTGCCC
AATGCCAGCTTGATGATTATCGATAATCCTGAACGGTTGGGGCTGGCGCAGTTACATCAGTTACGTGGGCGTGTCGGGCG
CGGTGCTGTCGCTTCCCACTGCGTATTACTCTATAAAACGCCATTAAGTAAAACCGCTCAAATGCGGTTGCAGGTATTAC
GTGATAGCAATGATGGTTTTGTGATTGCACAGCGAGATCTAGAAATCCGTGGCCCCGGTGAGCTATTGGGCACACGGCAA
ACAGGTAGCGCAGAGTTTAAGGTTGCCGACCTACTTCGTGATCAAGCGATGATCCCAGAAGTTCAGCGGGTCGCCCGTCA
TCTGCATCAACAGTACCCTGAACATGCCAAGGCATTGATAGAACGCTGGTTGCCGGAGCGGGTACGGTATACCAATGCGT
AA

Upstream 100 bases:

>100_bases
TGCCAAACGTAAAGGGCTCCCCCAACCTCATATTGATGAACAAGGCCAAATCATTGCCGATGCGCAATGGTGGTCGGCCA
TGCAAGCCACGGAGTCTTAA

Downstream 100 bases:

>100_bases
AGGGTGCAAATGGCAGGGCCGATAAAAAACCCGCTCTGTCAGCCCTAATATCCTCAAAATTCGTGCTCATCAACCTCAGC
CTCATTCATGAGGCTCAGAC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MKGRLLDAVPLSTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYRIGDLLPGLSVTVEGEVLRSDISFGRRRM
MTCQISDGSGVLTLRFFNFNAAMKNSLSVGKHVIAYGEAKRGNNGPEIIHPEYRVHGENIGVELQESLTPVYPTTEGIRQ
ATLRKLIDQALAMLDTCVIAELLPIELSRSLISLPEAIHTLHRPPADIQLADLEQGKHPAQRRLIMEELLAHNLSMLAVR
AGAQSYRALPLMAEEQLKQRFLAALPFTPTQAQQRVVAEIERDMTQSFPMMRLIQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHATTFRQWLEPLGFSVGWLAGKQKGKARLAQQEAVASGQVSMVIGTHAMFQEQVQFSGLALVIIDEQH
RFGVHQRLTLWEKGEEQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRSDVIQRVKNACL
EEGRQAYWVCTLIEESELLEAQAAEVTCEELKIALPEIKVGLVHGRMKGPEKQAIMLAFKQGELQLLVATTVIEVGVDVP
NASLMIIDNPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQMRLQVLRDSNDGFVIAQRDLEIRGPGELLGTRQ
TGSAEFKVADLLRDQAMIPEVQRVARHLHQQYPEHAKALIERWLPERVRYTNA

Sequences:

>Translated_693_residues
MKGRLLDAVPLSTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYRIGDLLPGLSVTVEGEVLRSDISFGRRRM
MTCQISDGSGVLTLRFFNFNAAMKNSLSVGKHVIAYGEAKRGNNGPEIIHPEYRVHGENIGVELQESLTPVYPTTEGIRQ
ATLRKLIDQALAMLDTCVIAELLPIELSRSLISLPEAIHTLHRPPADIQLADLEQGKHPAQRRLIMEELLAHNLSMLAVR
AGAQSYRALPLMAEEQLKQRFLAALPFTPTQAQQRVVAEIERDMTQSFPMMRLIQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHATTFRQWLEPLGFSVGWLAGKQKGKARLAQQEAVASGQVSMVIGTHAMFQEQVQFSGLALVIIDEQH
RFGVHQRLTLWEKGEEQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRSDVIQRVKNACL
EEGRQAYWVCTLIEESELLEAQAAEVTCEELKIALPEIKVGLVHGRMKGPEKQAIMLAFKQGELQLLVATTVIEVGVDVP
NASLMIIDNPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQMRLQVLRDSNDGFVIAQRDLEIRGPGELLGTRQ
TGSAEFKVADLLRDQAMIPEVQRVARHLHQQYPEHAKALIERWLPERVRYTNA
>Mature_693_residues
MKGRLLDAVPLSTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYRIGDLLPGLSVTVEGEVLRSDISFGRRRM
MTCQISDGSGVLTLRFFNFNAAMKNSLSVGKHVIAYGEAKRGNNGPEIIHPEYRVHGENIGVELQESLTPVYPTTEGIRQ
ATLRKLIDQALAMLDTCVIAELLPIELSRSLISLPEAIHTLHRPPADIQLADLEQGKHPAQRRLIMEELLAHNLSMLAVR
AGAQSYRALPLMAEEQLKQRFLAALPFTPTQAQQRVVAEIERDMTQSFPMMRLIQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHATTFRQWLEPLGFSVGWLAGKQKGKARLAQQEAVASGQVSMVIGTHAMFQEQVQFSGLALVIIDEQH
RFGVHQRLTLWEKGEEQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRSDVIQRVKNACL
EEGRQAYWVCTLIEESELLEAQAAEVTCEELKIALPEIKVGLVHGRMKGPEKQAIMLAFKQGELQLLVATTVIEVGVDVP
NASLMIIDNPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQMRLQVLRDSNDGFVIAQRDLEIRGPGELLGTRQ
TGSAEFKVADLLRDQAMIPEVQRVARHLHQQYPEHAKALIERWLPERVRYTNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=81.5295815295815, Blast_Score=1147, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=426, Percent_Identity=36.8544600938967, Blast_Score=236, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76661; Mature: 76661

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRLLDAVPLSTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYRIGDLLPGL
CCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
SVTVEGEVLRSDISFGRRRMMTCQISDGSGVLTLRFFNFNAAMKNSLSVGKHVIAYGEAK
EEEECHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECCHHHHCCHHHCCCEEEECCCC
RGNNGPEIIHPEYRVHGENIGVELQESLTPVYPTTEGIRQATLRKLIDQALAMLDTCVIA
CCCCCCCEECCCEEECCCCCCEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLPIELSRSLISLPEAIHTLHRPPADIQLADLEQGKHPAQRRLIMEELLAHNLSMLAVR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHH
AGAQSYRALPLMAEEQLKQRFLAALPFTPTQAQQRVVAEIERDMTQSFPMMRLIQGDVGS
HCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
GKTLVAALAALRAIAHGKQVALMAPTELLAEQHATTFRQWLEPLGFSVGWLAGKQKGKAR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHH
LAQQEAVASGQVSMVIGTHAMFQEQVQFSGLALVIIDEQHRFGVHQRLTLWEKGEEQGFH
HHHHHHHHCCCEEEEECHHHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRSDVIQRVKNACL
CCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
EEGRQAYWVCTLIEESELLEAQAAEVTCEELKIALPEIKVGLVHGRMKGPEKQAIMLAFK
HCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEE
QGELQLLVATTVIEVGVDVPNASLMIIDNPERLGLAQLHQLRGRVGRGAVASHCVLLYKT
CCCEEEEEEHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHCEEEEEEC
PLSKTAQMRLQVLRDSNDGFVIAQRDLEIRGPGELLGTRQTGSAEFKVADLLRDQAMIPE
CCCHHHHHHHHHHCCCCCCEEEEECCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHCCHH
VQRVARHLHQQYPEHAKALIERWLPERVRYTNA
HHHHHHHHHHHCCHHHHHHHHHHCHHHHCCCCC
>Mature Secondary Structure
MKGRLLDAVPLSTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYRIGDLLPGL
CCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
SVTVEGEVLRSDISFGRRRMMTCQISDGSGVLTLRFFNFNAAMKNSLSVGKHVIAYGEAK
EEEECHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECCHHHHCCHHHCCCEEEECCCC
RGNNGPEIIHPEYRVHGENIGVELQESLTPVYPTTEGIRQATLRKLIDQALAMLDTCVIA
CCCCCCCEECCCEEECCCCCCEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLPIELSRSLISLPEAIHTLHRPPADIQLADLEQGKHPAQRRLIMEELLAHNLSMLAVR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHH
AGAQSYRALPLMAEEQLKQRFLAALPFTPTQAQQRVVAEIERDMTQSFPMMRLIQGDVGS
HCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
GKTLVAALAALRAIAHGKQVALMAPTELLAEQHATTFRQWLEPLGFSVGWLAGKQKGKAR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHH
LAQQEAVASGQVSMVIGTHAMFQEQVQFSGLALVIIDEQHRFGVHQRLTLWEKGEEQGFH
HHHHHHHHCCCEEEEECHHHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRSDVIQRVKNACL
CCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
EEGRQAYWVCTLIEESELLEAQAAEVTCEELKIALPEIKVGLVHGRMKGPEKQAIMLAFK
HCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEE
QGELQLLVATTVIEVGVDVPNASLMIIDNPERLGLAQLHQLRGRVGRGAVASHCVLLYKT
CCCEEEEEEHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHCEEEEEEC
PLSKTAQMRLQVLRDSNDGFVIAQRDLEIRGPGELLGTRQTGSAEFKVADLLRDQAMIPE
CCCHHHHHHHHHHCCCCCCEEEEECCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHCCHH
VQRVARHLHQQYPEHAKALIERWLPERVRYTNA
HHHHHHHHHHHCCHHHHHHHHHHCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]