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The map label for this gene is wecF [H]

Identifier: 170026234

GI number: 170026234

Start: 4437937

End: 4439022

Strand: Reverse

Name: wecF [H]

Synonym: YPK_4024

Alternate gene names: 170026234

Gene position: 4439022-4437937 (Counterclockwise)

Preceding gene: 170026235

Following gene: 170026233

Centisome position: 94.66

GC content: 50.28

Gene sequence:

>1086_bases
ATGATAACCCTGACTCATGTACTGGGATCTGATATCCCGCACCATAATCTGACCGTGTTGCGTTTCTTTAATGACGTGCT
GGCGAAATGCCTGCCTGTAGAACAGGTACGGCACTTTATGGTCGCGGCAAAAGAAACGGCCCCCTTTTCGTCATTCCCGC
AGTTGGATATCAACACGTACAGTGATAAAAAAGCGTTGGCTGAGGCGGTTATTGCCCGTGCACAGGCGGATCGCAGTGCG
CGTTTCTTTTGGCACGGTCAGTTTAATGCCACTCTCTGGTTGGCGTTGCTAAGCGGTAAAATTAAGCCAGGGCAGGTGTA
TTGGCATGTCTGGGGTGCGGATTTATACGAAGATGCCAAAAGCTTAAAATTTCGTCTGTTTTACCTGCTGCGCCGCATAG
CACAAGGGCGGGTTGGGCACGTGTTTGCCACTCGGGGTGATTTAATTCATTACCAGCAGCGGCATCCTCGCGTGCCCGCC
TCATTACTCTACTTCCCGACCCGTATGGATCCGGCCCTGACCGCTATCAATATTGATAAACCCTTAGCTGGGCCGATGAC
AATCTTGGTGGGGAACTCCGGTGATACCACTAACCGCCATATAGAGGCGCTGAAGGCGATTCATCAGCAATTTGGCCCTG
ACGTCCGGGTGATTATTCCGATGGGCTATCCGGCGAATAACGAAGCGTATATTGAACAGGTTAGGCAGGCGGGGCTCGCA
CTGTTCTTGCAAGACAATCTACGTATCTTAACCGAACAGATCCCCTTTGATGATTATCTGAATATTCTGCGTGAATGTGA
TTTGGGCTATTTCATTTTTAACCGTCAACAAGGTATTGGTACCCTGTGTTTATTGACCCAGTTTGGCGTGCCCTTTGTGC
TAAGCCGTAAAAATCCGTTCTGGCAAGATTTGGCTGAGCAGCATATTCCCGTGTTCTTCTACGGTGACACTCTGGACGAG
CCGCTGATCCGTGAGGCACAACGTCAACTGGCAGGGTTAGATAAACAAGCGATCGCTTTCTTCAATCCAAATTATATTGA
GGGCTGGAAGCAAGCGTTGGCTCTGGCAGCGGGGGAACACCCATGA

Upstream 100 bases:

>100_bases
TATATGGCAACGTATATCGTCTATTTTGCGCTCTGTAGCTGCGCATTCCTTGTGTATCGTAGACACTCAGCACCGTAAAC
ACTCTTTACAGTAGAAAAAA

Downstream 100 bases:

>100_bases
CGCTGGGGCAATTTGGCGGTCTATTTTGTATTTATTTGATAGCAGTCATTTTTATTCTGACACTAACCTATCAGGAATTT
CGGCGGGTTAAGTTTAACTT

Product: 4-alpha-L-fucosyltransferase

Products: NA

Alternate protein names: TDP-Fuc4NAc:lipid II Fuc4NAc transferase; Fuc4NAc transferase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTYSDKKALAEAVIARAQADRSA
RFFWHGQFNATLWLALLSGKIKPGQVYWHVWGADLYEDAKSLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPA
SLLYFPTRMDPALTAINIDKPLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
LFLQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPFWQDLAEQHIPVFFYGDTLDE
PLIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEHP

Sequences:

>Translated_361_residues
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTYSDKKALAEAVIARAQADRSA
RFFWHGQFNATLWLALLSGKIKPGQVYWHVWGADLYEDAKSLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPA
SLLYFPTRMDPALTAINIDKPLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
LFLQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPFWQDLAEQHIPVFFYGDTLDE
PLIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEHP
>Mature_361_residues
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTYSDKKALAEAVIARAQADRSA
RFFWHGQFNATLWLALLSGKIKPGQVYWHVWGADLYEDAKSLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPA
SLLYFPTRMDPALTAINIDKPLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
LFLQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPFWQDLAEQHIPVFFYGDTLDE
PLIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEHP

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 56 family [H]

Homologues:

Organism=Escherichia coli, GI48994971, Length=359, Percent_Identity=63.5097493036212, Blast_Score=486, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009993 [H]

Pfam domain/function: PF07429 Fuc4NAc_transf [H]

EC number: NA

Molecular weight: Translated: 41052; Mature: 41052

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTY
CEEEEEHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SDKKALAEAVIARAQADRSARFFWHGQFNATLWLALLSGKIKPGQVYWHVWGADLYEDAK
CHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHEEEHHHCCCCCCEEEEEEECCHHHHHHH
SLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPASLLYFPTRMDPALTAINIDK
HHHHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHCCCCCHHHEEECCCCCCCEEEEECCC
PLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCEE
LFLQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPF
EEEECCHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCEEEECCCCH
WQDLAEQHIPVFFYGDTLDEPLIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEH
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCC
P
C
>Mature Secondary Structure
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTY
CEEEEEHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SDKKALAEAVIARAQADRSARFFWHGQFNATLWLALLSGKIKPGQVYWHVWGADLYEDAK
CHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHEEEHHHCCCCCCEEEEEEECCHHHHHHH
SLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPASLLYFPTRMDPALTAINIDK
HHHHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHCCCCCHHHEEECCCCCCCEEEEECCC
PLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCEE
LFLQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPF
EEEECCHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCEEEECCCCH
WQDLAEQHIPVFFYGDTLDEPLIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEH
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA