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The map label for this gene is yifK [H]

Identifier: 170026231

GI number: 170026231

Start: 4433907

End: 4435298

Strand: Reverse

Name: yifK [H]

Synonym: YPK_4021

Alternate gene names: 170026231

Gene position: 4435298-4433907 (Counterclockwise)

Preceding gene: 170026232

Following gene: 170026226

Centisome position: 94.58

GC content: 49.78

Gene sequence:

>1392_bases
ATGGCAGACAACGCAGAGAAAAAAGGATTACACCGTGGGCTGGAAGCTCGGCATATCGAACTGATAGCGTTGGGCGGTAC
CATTGGTGTCGGGTTATTTATGGGGTCAGCAAGCACGTTGAAATGGGCAGGGCCGTCAGTATTACTGGCTTATATCATTG
CGGGCTTATTTGTATTCTTCATTATGCGCGCAATGGGGGAAATGCTGTATCTGGAGCCCGTGGCTGGATCCTTCGCAGTC
TATGCGCATAAGTATCTCAGTCCCTATTTTGGCTATCTGACGGCTTGGGGCTACTGGTTTATGTGGATTGCGGTGGGGAT
ATCTGAAATTACCGCCATTGGCGTCTATGTTCAGTTTTGGTTCCCAGAAATCCCGCAGTGGCTGCCGGCTATCGCTGGGG
TGGCGATTGTGGCATTAGCGAATCTGGCTGCGGTCAAATTGTATGGCGAGCTAGAGTTTTGGTTTGCCATGATCAAGGTC
ACGACGATCATTGTGATGATTTTGGTTGGCTTAGGCGTGATATTTTTTGGCTTCGGTAATCACGGCCAGCCGATTGGCTT
CGATAATCTGACCGCCCATGGCGGTTTCTTTGCCGGGGGGTGGAAAGGCTTCCTGTTTGCGCTGTGTATTGTGGTCGCGT
CTTACCAAGGTGTTGAACTGGTCGGTATTACGGCGGGAGAAGCCAGAAATCCACAGGTGACGTTAAGAAGAGCGATCAAC
AACATCTTATGGCGAATTTTGATTTTCTACGTCGGTGCAATATTTGTCATTGTCACCATTTTTCCCTGGAATGGGATTGG
TACAGAGGGTAGCCCCTTCGTACTGACCTTCGCCAAAATAGGAATAGTGGCCGCGGCGGGTATTATTAACTTCGTGATAC
TGACCGCCGCTCTCTCAGGTTGTAACAGTGGTATGTATAGCGGCGGGCGTATGTTGTATGCCTTGGCAAAAAATCGTCAG
CTACCGGCCGGCCTGACCAAACTGTCGGCTAGCGGTGTACCGGTGTACTGCATTGCGATCACCATCCTGTGTCTACTGGT
GGGGTCGAGCCTGAATTACATTATTCCCAACCCGCAGCAAGTGTTTGTTTATGTCTACAGTGCCAGCGTGTTACCTGGCA
TGGTGCCGTGGTTTGTGGTCTTGGTCTGTCAGTTACGTTTTCGGCAGGTACATAAAGCTGCCCTACAGCAGCACCCGTTT
AAATCTATCCTATTCCCCTATGTGAACTACCTCACCATCGCATTCCTGATTTGTGTATTAGTGGGAATGGGGATAAACCC
AGATACTCGCTTATCATTACTGGTTGGGGCAATTTTTCTGGCATTAGTGACGGGATGCTATTTTGTGCTGGGGATGCATA
AACCCAAGGCCATGGAAGCGGAACGCCTATAA

Upstream 100 bases:

>100_bases
TATTGAATATTTAAATTCAGTCATTAAATTCATTTGCATCATAACGATAATAACCGGGGATTCCGGAGCAGATATACACC
AGTCAGTTTACAGAGGATAT

Downstream 100 bases:

>100_bases
AATCGGCAATCAAGACGGTGTGGGGGCTATTATTCACTGAGTTTTGTGGCAGAGTGAGCAAAGCGTAAGCAAACGCATCA
TTTCTTCTAAAAAAGCACTA

Product: putative transport protein YifK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MADNAEKKGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFFIMRAMGEMLYLEPVAGSFAV
YAHKYLSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFWFPEIPQWLPAIAGVAIVALANLAAVKLYGELEFWFAMIKV
TTIIVMILVGLGVIFFGFGNHGQPIGFDNLTAHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEARNPQVTLRRAIN
NILWRILIFYVGAIFVIVTIFPWNGIGTEGSPFVLTFAKIGIVAAAGIINFVILTAALSGCNSGMYSGGRMLYALAKNRQ
LPAGLTKLSASGVPVYCIAITILCLLVGSSLNYIIPNPQQVFVYVYSASVLPGMVPWFVVLVCQLRFRQVHKAALQQHPF
KSILFPYVNYLTIAFLICVLVGMGINPDTRLSLLVGAIFLALVTGCYFVLGMHKPKAMEAERL

Sequences:

>Translated_463_residues
MADNAEKKGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFFIMRAMGEMLYLEPVAGSFAV
YAHKYLSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFWFPEIPQWLPAIAGVAIVALANLAAVKLYGELEFWFAMIKV
TTIIVMILVGLGVIFFGFGNHGQPIGFDNLTAHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEARNPQVTLRRAIN
NILWRILIFYVGAIFVIVTIFPWNGIGTEGSPFVLTFAKIGIVAAAGIINFVILTAALSGCNSGMYSGGRMLYALAKNRQ
LPAGLTKLSASGVPVYCIAITILCLLVGSSLNYIIPNPQQVFVYVYSASVLPGMVPWFVVLVCQLRFRQVHKAALQQHPF
KSILFPYVNYLTIAFLICVLVGMGINPDTRLSLLVGAIFLALVTGCYFVLGMHKPKAMEAERL
>Mature_462_residues
ADNAEKKGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFFIMRAMGEMLYLEPVAGSFAVY
AHKYLSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFWFPEIPQWLPAIAGVAIVALANLAAVKLYGELEFWFAMIKVT
TIIVMILVGLGVIFFGFGNHGQPIGFDNLTAHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEARNPQVTLRRAINN
ILWRILIFYVGAIFVIVTIFPWNGIGTEGSPFVLTFAKIGIVAAAGIINFVILTAALSGCNSGMYSGGRMLYALAKNRQL
PAGLTKLSASGVPVYCIAITILCLLVGSSLNYIIPNPQQVFVYVYSASVLPGMVPWFVVLVCQLRFRQVHKAALQQHPFK
SILFPYVNYLTIAFLICVLVGMGINPDTRLSLLVGAIFLALVTGCYFVLGMHKPKAMEAERL

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994972, Length=463, Percent_Identity=79.4816414686825, Blast_Score=719, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=435, Percent_Identity=44.8275862068966, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1786602, Length=436, Percent_Identity=46.1009174311927, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1790653, Length=466, Percent_Identity=39.6995708154506, Blast_Score=338, Evalue=6e-94,
Organism=Escherichia coli, GI1786302, Length=461, Percent_Identity=38.8286334056399, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI87081915, Length=393, Percent_Identity=39.9491094147583, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI87081708, Length=468, Percent_Identity=36.1111111111111, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1788480, Length=449, Percent_Identity=37.4164810690423, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1789017, Length=436, Percent_Identity=34.4036697247706, Blast_Score=252, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6324061, Length=442, Percent_Identity=36.4253393665158, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6320772, Length=446, Percent_Identity=33.4080717488789, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6324924, Length=439, Percent_Identity=31.2072892938497, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324059, Length=440, Percent_Identity=32.2727272727273, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6324990, Length=411, Percent_Identity=31.1435523114355, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6322892, Length=415, Percent_Identity=32.0481927710843, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6321629, Length=420, Percent_Identity=27.8571428571429, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6321053, Length=420, Percent_Identity=27.3809523809524, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322967, Length=396, Percent_Identity=29.040404040404, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6319608, Length=430, Percent_Identity=27.2093023255814, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=405, Percent_Identity=26.9135802469136, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319542, Length=408, Percent_Identity=27.2058823529412, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6319543, Length=401, Percent_Identity=27.6807980049875, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324553, Length=399, Percent_Identity=29.3233082706767, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6320251, Length=399, Percent_Identity=27.5689223057644, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324981, Length=413, Percent_Identity=29.2978208232446, Blast_Score=136, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6320717, Length=406, Percent_Identity=23.1527093596059, Blast_Score=126, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320364, Length=490, Percent_Identity=23.265306122449, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50345; Mature: 50214

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNAEKKGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFF
CCCCCHHHHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
IMRAMGEMLYLEPVAGSFAVYAHKYLSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFW
HHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPEIPQWLPAIAGVAIVALANLAAVKLYGELEFWFAMIKVTTIIVMILVGLGVIFFGFGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HGQPIGFDNLTAHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEARNPQVTLRRAIN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
NILWRILIFYVGAIFVIVTIFPWNGIGTEGSPFVLTFAKIGIVAAAGIINFVILTAALSG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
CNSGMYSGGRMLYALAKNRQLPAGLTKLSASGVPVYCIAITILCLLVGSSLNYIIPNPQQ
CCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCE
VFVYVYSASVLPGMVPWFVVLVCQLRFRQVHKAALQQHPFKSILFPYVNYLTIAFLICVL
EEEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VGMGINPDTRLSLLVGAIFLALVTGCYFVLGMHKPKAMEAERL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ADNAEKKGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFF
CCCCHHHHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
IMRAMGEMLYLEPVAGSFAVYAHKYLSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFW
HHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPEIPQWLPAIAGVAIVALANLAAVKLYGELEFWFAMIKVTTIIVMILVGLGVIFFGFGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HGQPIGFDNLTAHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEARNPQVTLRRAIN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
NILWRILIFYVGAIFVIVTIFPWNGIGTEGSPFVLTFAKIGIVAAAGIINFVILTAALSG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
CNSGMYSGGRMLYALAKNRQLPAGLTKLSASGVPVYCIAITILCLLVGSSLNYIIPNPQQ
CCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCE
VFVYVYSASVLPGMVPWFVVLVCQLRFRQVHKAALQQHPFKSILFPYVNYLTIAFLICVL
EEEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VGMGINPDTRLSLLVGAIFLALVTGCYFVLGMHKPKAMEAERL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]