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The map label for this gene is pucG [H]

Identifier: 170025542

GI number: 170025542

Start: 3646100

End: 3647425

Strand: Reverse

Name: pucG [H]

Synonym: YPK_3325

Alternate gene names: 170025542

Gene position: 3647425-3646100 (Counterclockwise)

Preceding gene: 170025543

Following gene: 170025541

Centisome position: 77.78

GC content: 52.64

Gene sequence:

>1326_bases
ATGTCAGAGATAAACCCTAATCCCTTGTTCAGGCAGATAAATCCACCTGCCCGTTTATTAATGGGGCCGGGACCGATCAA
TGCCGATCCACGGGTATTACGGGCGATGTCCAGCCAGTTGATCGGCCAATATGATCCGGCGATGACCGATTATATGAATC
AGGTGATGGCGTTGTATCGGGGGGTTTTCCGGACGGAGAATCGCTGGACAATGTTGATCGATGGAACCTCGCGTGCGGGC
ATTGAGGCCGTTTTACTGTCGGCGATCCGTCCCGGTGACAAAGTGCTGATCCCGGTTTTTGGCCGTTTTGGCTATTTATT
GTGTGAAATTGCCCGCCGTTGCCGTGCCGAAGTGCATATTATCGAGGTGCCGTGGGGGGAGGTATTCAGCCCGGATAGAA
TTGAAGATGCCATCAAGCACATTCGCCCGCGCCTGTTACTGACCGTGCAGGGCGATACCTCTACCACGATGTTGCAACCG
TTAGCTGAGCTGGGTGATATTTGTCGCCGCCATCAGGTGTTGTTCTATACCGATGCCACCGCGTCACTGGGTGGGAATCC
ATTGGAGACGGATGCCTGGGGGTTGGATGCGGTCTCTGCTGGGTTGCAAAAGTGCCTTGGCGGGCCATCCGGCAGTTCAC
CGATTACCCTGAGTCCACAATTCGCCGAACAAATTCGTCGCCGTAAATGTATTGAGCAGGGTATTCGTACTTCAGATCAT
GCGGATGGCGACGAGGAGATGATCTACTCCAATTACTTTGATCTGGGCATGATCATGGATTATTGGGGGCCGGAACGGCT
GAATCATCATACCGAAGCCACCAGTATGTTATTCGCCGCACGTGAATGCGCCAGAGTGATATTAGAGGAAGGGCTGGATC
ATGGGATTGCCCGCCATGCCTTACACGGTAGCGCATTGTTGGCCGGTATTCAGGGGATGGGGCTTTCGGTGTTTGGTGAT
ATAAAGCATCGTATGAATAACGTACTGGGCGTGGTCATACCGAAAGGTATTCCCGGTGAACAAGTGCGGCAACTGCTGTT
GAATGACTTTGGTATTGAGATTGGTACCTCGTTCGGGCCGTTGAATGGCAAAATTTGGCGTATCGGCACCATGGGGTATA
ACGCCCGTAAAGATTGCGTCATGCAAACGCTAGTGGCGCTGGAGGCGGTATTGAACCGTTTAGGGTTTACCACGGTTCAG
GGCGCAGGGTTACAAGCCGCATGGGATGTCTATCAGGTGGATAGTGCTCATCAGGCGGATAGTGCTCATCAGGCGGATAG
TGCTCAAAGGAATAGCGATCATGCTCAACTGAATGGAGCGAATTGA

Upstream 100 bases:

>100_bases
GCCGATCCACAGACCCGCGAATTGAAACAGTTTATATCGTCAGTCCGCGGTTTATCTGGCCCTGCCTGATGGTGATTTAT
ATAAAGGATGGAGATTTTTT

Downstream 100 bases:

>100_bases
TGGGCGTAACTCTGCCGGATATTGAGGCTGAACAGGCCGCATTACAGGTCTTGGCCCGTTGTGACGTATTGGCGGCAATC
AGTGAATCCCCCGAAGGGCT

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSEINPNPLFRQINPPARLLMGPGPINADPRVLRAMSSQLIGQYDPAMTDYMNQVMALYRGVFRTENRWTMLIDGTSRAG
IEAVLLSAIRPGDKVLIPVFGRFGYLLCEIARRCRAEVHIIEVPWGEVFSPDRIEDAIKHIRPRLLLTVQGDTSTTMLQP
LAELGDICRRHQVLFYTDATASLGGNPLETDAWGLDAVSAGLQKCLGGPSGSSPITLSPQFAEQIRRRKCIEQGIRTSDH
ADGDEEMIYSNYFDLGMIMDYWGPERLNHHTEATSMLFAARECARVILEEGLDHGIARHALHGSALLAGIQGMGLSVFGD
IKHRMNNVLGVVIPKGIPGEQVRQLLLNDFGIEIGTSFGPLNGKIWRIGTMGYNARKDCVMQTLVALEAVLNRLGFTTVQ
GAGLQAAWDVYQVDSAHQADSAHQADSAQRNSDHAQLNGAN

Sequences:

>Translated_441_residues
MSEINPNPLFRQINPPARLLMGPGPINADPRVLRAMSSQLIGQYDPAMTDYMNQVMALYRGVFRTENRWTMLIDGTSRAG
IEAVLLSAIRPGDKVLIPVFGRFGYLLCEIARRCRAEVHIIEVPWGEVFSPDRIEDAIKHIRPRLLLTVQGDTSTTMLQP
LAELGDICRRHQVLFYTDATASLGGNPLETDAWGLDAVSAGLQKCLGGPSGSSPITLSPQFAEQIRRRKCIEQGIRTSDH
ADGDEEMIYSNYFDLGMIMDYWGPERLNHHTEATSMLFAARECARVILEEGLDHGIARHALHGSALLAGIQGMGLSVFGD
IKHRMNNVLGVVIPKGIPGEQVRQLLLNDFGIEIGTSFGPLNGKIWRIGTMGYNARKDCVMQTLVALEAVLNRLGFTTVQ
GAGLQAAWDVYQVDSAHQADSAHQADSAQRNSDHAQLNGAN
>Mature_440_residues
SEINPNPLFRQINPPARLLMGPGPINADPRVLRAMSSQLIGQYDPAMTDYMNQVMALYRGVFRTENRWTMLIDGTSRAGI
EAVLLSAIRPGDKVLIPVFGRFGYLLCEIARRCRAEVHIIEVPWGEVFSPDRIEDAIKHIRPRLLLTVQGDTSTTMLQPL
AELGDICRRHQVLFYTDATASLGGNPLETDAWGLDAVSAGLQKCLGGPSGSSPITLSPQFAEQIRRRKCIEQGIRTSDHA
DGDEEMIYSNYFDLGMIMDYWGPERLNHHTEATSMLFAARECARVILEEGLDHGIARHALHGSALLAGIQGMGLSVFGDI
KHRMNNVLGVVIPKGIPGEQVRQLLLNDFGIEIGTSFGPLNGKIWRIGTMGYNARKDCVMQTLVALEAVLNRLGFTTVQG
AGLQAAWDVYQVDSAHQADSAHQADSAQRNSDHAQLNGAN

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=391, Percent_Identity=31.7135549872123, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17536281, Length=378, Percent_Identity=34.1269841269841, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI17530823, Length=400, Percent_Identity=33.75, Blast_Score=221, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 48451; Mature: 48320

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEINPNPLFRQINPPARLLMGPGPINADPRVLRAMSSQLIGQYDPAMTDYMNQVMALYR
CCCCCCCCCCCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GVFRTENRWTMLIDGTSRAGIEAVLLSAIRPGDKVLIPVFGRFGYLLCEIARRCRAEVHI
HHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEE
IEVPWGEVFSPDRIEDAIKHIRPRLLLTVQGDTSTTMLQPLAELGDICRRHQVLFYTDAT
EECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEECCH
ASLGGNPLETDAWGLDAVSAGLQKCLGGPSGSSPITLSPQFAEQIRRRKCIEQGIRTSDH
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCC
ADGDEEMIYSNYFDLGMIMDYWGPERLNHHTEATSMLFAARECARVILEEGLDHGIARHA
CCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHGSALLAGIQGMGLSVFGDIKHRMNNVLGVVIPKGIPGEQVRQLLLNDFGIEIGTSFGP
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEECCCCCC
LNGKIWRIGTMGYNARKDCVMQTLVALEAVLNRLGFTTVQGAGLQAAWDVYQVDSAHQAD
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHCCCCCCCCC
SAHQADSAQRNSDHAQLNGAN
CHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SEINPNPLFRQINPPARLLMGPGPINADPRVLRAMSSQLIGQYDPAMTDYMNQVMALYR
CCCCCCCCCCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GVFRTENRWTMLIDGTSRAGIEAVLLSAIRPGDKVLIPVFGRFGYLLCEIARRCRAEVHI
HHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEE
IEVPWGEVFSPDRIEDAIKHIRPRLLLTVQGDTSTTMLQPLAELGDICRRHQVLFYTDAT
EECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEECCH
ASLGGNPLETDAWGLDAVSAGLQKCLGGPSGSSPITLSPQFAEQIRRRKCIEQGIRTSDH
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCC
ADGDEEMIYSNYFDLGMIMDYWGPERLNHHTEATSMLFAARECARVILEEGLDHGIARHA
CCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHGSALLAGIQGMGLSVFGDIKHRMNNVLGVVIPKGIPGEQVRQLLLNDFGIEIGTSFGP
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEECCCCCC
LNGKIWRIGTMGYNARKDCVMQTLVALEAVLNRLGFTTVQGAGLQAAWDVYQVDSAHQAD
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHCCCCCCCCC
SAHQADSAQRNSDHAQLNGAN
CHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]