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The map label for this gene is clpX [H]

Identifier: 170025450

GI number: 170025450

Start: 3536309

End: 3537580

Strand: Reverse

Name: clpX [H]

Synonym: YPK_3233

Alternate gene names: 170025450

Gene position: 3537580-3536309 (Counterclockwise)

Preceding gene: 170025451

Following gene: 170025449

Centisome position: 75.44

GC content: 48.35

Gene sequence:

>1272_bases
ATGACAGATAAGCGCAAAGACGGTTCAGGAAAGCTGCTGTATTGCTCTTTCTGCGGCAAAAGCCAGCATGAAGTGCGTAA
GCTAATTGCCGGGCCGTCAGTGTATATCTGCGATGAATGTGTCGATTTGTGTAATGACATTATTCGCGAAGAGATTAAGG
AAGTTTCCCCGCACCGGGATCGCAGTTCACTGCCAACACCGCATGAAATTCGCCACCACCTTGATGATTATGTCATCGGG
CAGGAACCTGCGAAAAAAGTGCTGGCAGTTGCGGTGTATAACCACTACAAGCGTCTGCGTAACGGTGATACCAGTAATGG
TATTGAACTGGGTAAAAGTAATATTTTGCTGATTGGTCCGACAGGGAGCGGTAAAACGCTGTTGGCGGAAACATTGGCTC
GCCTCCTGGACGTGCCATTTACTATGGCGGACGCGACTACGCTGACTGAAGCTGGCTATGTGGGTGAAGATGTTGAAAAC
ATCATTCAGAAGCTACTACAGAAGTGTGATTACGACGTACAGAAAGCGCAACGTGGTATCGTCTATATCGATGAAATTGA
TAAAATTTCACGCAAGTCTGATAATCCGTCGATCACCCGTGATGTCTCAGGTGAAGGCGTACAGCAGGCTCTGCTGAAAT
TGATCGAAGGGACCATTGCTGCGGTACCGCCACAAGGTGGTCGTAAGCATCCACAGCAGGAGTTTTTGCAGGTTGATACC
TCCAAGATTCTGTTTATCTGTGGTGGTGCTTTTGCCGGTTTGGACAAAGTTATTGGGCAGCGTATTAATACCGGCTCAGG
TATCGGCTTTGGCGCAGTGGTAAAAGGCCAATCAGAAAAGGCAACAGAAGGTGAGTTGCTGAGTCAGGTTGAGCCAGAAG
ACCTGATCAAATTTGGCTTAATCCCTGAATTTATCGGTCGTTTGCCGGTAGTCGCCACATTGAGCGAACTGAGTGAGGAT
GCACTGATCCAGATCCTTAAAGAGCCGAAAAATGCACTGACCAAGCAATATCAGGCATTATTCAGCCTTGAAGGTGTTGA
ACTCGAGTTCCGTGACGAAGCATTGACTGCGATTGCCAAGAAAGCGATGGCGCGTAAAACAGGTGCTCGTGGGCTGCGCT
CCATTGTCGAAGGTGCTTTGCTGGATACGATGTATGATCTGCCATCAATGGATAGCGTAGAGAAGGTGGTCGTGGATGAA
TCAGTTATTGCTGGTCAATCTGCGCCGATGCTGATTTATGGTCAGCCCGAAGCGCAAGCTTCTGGTGAATAA

Upstream 100 bases:

>100_bases
GCTATCCGTTGAACGTTAACGTGATGTCCAGAAATAGCGAGAATAGTCTCCCTGCCACCATAGTTTCGGGTGTGGCAGAT
ACTAAAGAAGAGGTTTACTG

Downstream 100 bases:

>100_bases
TTAACCAGATTGTCCAGGCAGTTAGTATGACAATGGGGGATTTTATCCCCCATTTCTTTTTCCTCGCATTGTTATCGTTG
AATGTAAGACATTCGTCCCC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRDRSSLPTPHEIRHHLDDYVIG
QEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIGQRINTGSGIGFGAVVKGQSEKATEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLSELSED
ALIQILKEPKNALTKQYQALFSLEGVELEFRDEALTAIAKKAMARKTGARGLRSIVEGALLDTMYDLPSMDSVEKVVVDE
SVIAGQSAPMLIYGQPEAQASGE

Sequences:

>Translated_423_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRDRSSLPTPHEIRHHLDDYVIG
QEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIGQRINTGSGIGFGAVVKGQSEKATEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLSELSED
ALIQILKEPKNALTKQYQALFSLEGVELEFRDEALTAIAKKAMARKTGARGLRSIVEGALLDTMYDLPSMDSVEKVVVDE
SVIAGQSAPMLIYGQPEAQASGE
>Mature_422_residues
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRDRSSLPTPHEIRHHLDDYVIGQ
EPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENI
IQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDTS
KILFICGGAFAGLDKVIGQRINTGSGIGFGAVVKGQSEKATEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLSELSEDA
LIQILKEPKNALTKQYQALFSLEGVELEFRDEALTAIAKKAMARKTGARGLRSIVEGALLDTMYDLPSMDSVEKVVVDES
VIAGQSAPMLIYGQPEAQASGE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=429, Percent_Identity=45.4545454545455, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=92.688679245283, Blast_Score=805, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=45, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=45.9807073954984, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=45.9807073954984, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=394, Percent_Identity=38.8324873096447, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=40.5622489959839, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=40.2810304449649, Blast_Score=275, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=46.1059190031153, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=46.1059190031153, Blast_Score=286, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46033; Mature: 45902

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRD
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCC
RSSLPTPHEIRHHLDDYVIGQEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGP
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCCHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVIGQRINTGSGIGFGAVVKGQSEKATEGELLSQVEPEDLIKFGL
CEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHCCCHHHHHHHCC
IPEFIGRLPVVATLSELSEDALIQILKEPKNALTKQYQALFSLEGVELEFRDEALTAIAK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
KAMARKTGARGLRSIVEGALLDTMYDLPSMDSVEKVVVDESVIAGQSAPMLIYGQPEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCC
SGE
CCC
>Mature Secondary Structure 
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRD
CCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCC
RSSLPTPHEIRHHLDDYVIGQEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGP
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCCHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVIGQRINTGSGIGFGAVVKGQSEKATEGELLSQVEPEDLIKFGL
CEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHCCCHHHHHHHCC
IPEFIGRLPVVATLSELSEDALIQILKEPKNALTKQYQALFSLEGVELEFRDEALTAIAK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
KAMARKTGARGLRSIVEGALLDTMYDLPSMDSVEKVVVDESVIAGQSAPMLIYGQPEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCC
SGE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA