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The map label for this gene is ygbM [H]

Identifier: 170025047

GI number: 170025047

Start: 3109271

End: 3110065

Strand: Reverse

Name: ygbM [H]

Synonym: YPK_2823

Alternate gene names: 170025047

Gene position: 3110065-3109271 (Counterclockwise)

Preceding gene: 170025048

Following gene: 170025046

Centisome position: 66.32

GC content: 44.53

Gene sequence:

>795_bases
ATGCTCAAATTCGCAGCCAATCTAACGTGGTTATTTACCGAGGTGCCATTTTTACAGCGCTTTGCTTTGGCCGCTAAGGC
TGGGTTCCCGGCAGTAGAGTGCCTTTTCCCCTATCAGGAACAGATCGCCGATGTGCAACAAGCACAAAAAGCGAGCGGCA
TTCCGGTAGTTTTGATCAATGCCCCTGCGGGAGAATGGGAAAATGGCCAGCGGGGACTCGCCTCACTGCCCGATGTTGGC
GAGCCGTTTCGCCACAGTGTGCGGCTGGCGCGTGAATATGCCGTGGCATTGGGATGTAAACAGATTCATATCATGGCTGG
CAATAGAGAAGAGAGTATCACTTTCGATGAGCAATATGCGTTACTGATTGAACGATTACGTTATGCTGCAGACTATTTAA
TGGCTGACAATATCAGGGTGCTTATTGAACCTTTAAATAATGACAATATGCCGGGTTATTTTATTTCATCATTTCCGCTG
GCGGAAAAAATAATTCACCAGTGTGAGAGAAAGAATATTTTTTTACAGTTTGATGTTTACCATTGCCAAAAAATACACGG
CAACCTATGGGCCAACCTACAACATTACTGGCCGTTAATTTCACATATACAGATAGCCTCGGTACCTGAACGGCATGAAC
CGAATAAAGGCGAGGTCAACTACCCTTGGTTATTCCAACAACTGGTAATAAAAAATTATCCAGGCTGGATTGGATGTGAA
TATCAACCCGAAAATGAAACATTCTCAGGGTTGGGGTGGTTGGGAAAAAATAAAAATATCAAGGCGTTTTCATAG

Upstream 100 bases:

>100_bases
CTGACATTATTTCAGATGGCAATCTGCCACTTGTCGCACAGAAACAGATCAAAGAGTCCGGCGTTAAATTACATCTGGTC
AACAAAGAGGTAAGAGCCCC

Downstream 100 bases:

>100_bases
CGCCGCTGGCCACTGTATAGCTAACTGTGATAGGCCACACTTCGGTGTGGCTGTCTTTTTTCATCTTATATAAAAAAACA
TTCACGCGGTCCGCAAAAAA

Product: hydroxypyruvate isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLKFAANLTWLFTEVPFLQRFALAAKAGFPAVECLFPYQEQIADVQQAQKASGIPVVLINAPAGEWENGQRGLASLPDVG
EPFRHSVRLAREYAVALGCKQIHIMAGNREESITFDEQYALLIERLRYAADYLMADNIRVLIEPLNNDNMPGYFISSFPL
AEKIIHQCERKNIFLQFDVYHCQKIHGNLWANLQHYWPLISHIQIASVPERHEPNKGEVNYPWLFQQLVIKNYPGWIGCE
YQPENETFSGLGWLGKNKNIKAFS

Sequences:

>Translated_264_residues
MLKFAANLTWLFTEVPFLQRFALAAKAGFPAVECLFPYQEQIADVQQAQKASGIPVVLINAPAGEWENGQRGLASLPDVG
EPFRHSVRLAREYAVALGCKQIHIMAGNREESITFDEQYALLIERLRYAADYLMADNIRVLIEPLNNDNMPGYFISSFPL
AEKIIHQCERKNIFLQFDVYHCQKIHGNLWANLQHYWPLISHIQIASVPERHEPNKGEVNYPWLFQQLVIKNYPGWIGCE
YQPENETFSGLGWLGKNKNIKAFS
>Mature_264_residues
MLKFAANLTWLFTEVPFLQRFALAAKAGFPAVECLFPYQEQIADVQQAQKASGIPVVLINAPAGEWENGQRGLASLPDVG
EPFRHSVRLAREYAVALGCKQIHIMAGNREESITFDEQYALLIERLRYAADYLMADNIRVLIEPLNNDNMPGYFISSFPL
AEKIIHQCERKNIFLQFDVYHCQKIHGNLWANLQHYWPLISHIQIASVPERHEPNKGEVNYPWLFQQLVIKNYPGWIGCE
YQPENETFSGLGWLGKNKNIKAFS

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=260, Percent_Identity=40.3846153846154, Blast_Score=194, Evalue=5e-50,
Organism=Homo sapiens, GI300068964, Length=244, Percent_Identity=38.9344262295082, Blast_Score=171, Evalue=5e-43,
Organism=Escherichia coli, GI1789095, Length=254, Percent_Identity=42.9133858267717, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1786718, Length=254, Percent_Identity=40.5511811023622, Blast_Score=211, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17552022, Length=249, Percent_Identity=36.9477911646586, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI17530883, Length=262, Percent_Identity=39.3129770992366, Blast_Score=176, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: NA

Molecular weight: Translated: 30237; Mature: 30237

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFAANLTWLFTEVPFLQRFALAAKAGFPAVECLFPYQEQIADVQQAQKASGIPVVLIN
CCEEECCEEEEEHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEEEE
APAGEWENGQRGLASLPDVGEPFRHSVRLAREYAVALGCKQIHIMAGNREESITFDEQYA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEHHHHH
LLIERLRYAADYLMADNIRVLIEPLNNDNMPGYFISSFPLAEKIIHQCERKNIFLQFDVY
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHCCEEEEEEHH
HCQKIHGNLWANLQHYWPLISHIQIASVPERHEPNKGEVNYPWLFQQLVIKNYPGWIGCE
HHHHHHCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECE
YQPENETFSGLGWLGKNKNIKAFS
ECCCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MLKFAANLTWLFTEVPFLQRFALAAKAGFPAVECLFPYQEQIADVQQAQKASGIPVVLIN
CCEEECCEEEEEHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEEEE
APAGEWENGQRGLASLPDVGEPFRHSVRLAREYAVALGCKQIHIMAGNREESITFDEQYA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEHHHHH
LLIERLRYAADYLMADNIRVLIEPLNNDNMPGYFISSFPLAEKIIHQCERKNIFLQFDVY
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHCCEEEEEEHH
HCQKIHGNLWANLQHYWPLISHIQIASVPERHEPNKGEVNYPWLFQQLVIKNYPGWIGCE
HHHHHHCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECE
YQPENETFSGLGWLGKNKNIKAFS
ECCCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]