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The map label for this gene is rtn [H]

Identifier: 170025010

GI number: 170025010

Start: 3073586

End: 3075166

Strand: Direct

Name: rtn [H]

Synonym: YPK_2785

Alternate gene names: 170025010

Gene position: 3073586-3075166 (Clockwise)

Preceding gene: 170025009

Following gene: 170025011

Centisome position: 65.54

GC content: 42.69

Gene sequence:

>1581_bases
ATGGGTTCAAACAGTGCGTTCTCCCGCAATATTTTGTCCAGACGCCATCTGGTAAAAAAGAGTATCCTCCTCGCGCTCTG
CTTTTTTATCTGTTTTGTCGTTATAACGTTGTCATTACTGTATCGCAGCAGTGAAAATAAATTAACAACACAAAGTGGTA
ATATTATCACCTATGCCTCTCATTTCCTTAATGAAATAACAACGACCATGTCTCAGCTTATCCCACTGAGCACCCAATCG
TGCGAACAAGCCAGCCCAACTCTTCATTATCGTGCCGCCTTTACCAATGGTGTCAGAGCCTTTTTATTGGTCAGGGAAGG
CGTTGCTTATTGCTCCTCGGCAACGGGTGAAATGCACACGCCAGTCAGTACGATCTACCCCAAAGTTAATTTATCCCAGC
CACTGGATTTTAAAATTCAGCAAGGCACCCCCATGATGCCAAACAAGCCTGCAATTGCCGTATGGCTGCGTCAAGCAGGC
CGTGGAGATACGGGAATATTGGCGACGATGGAATTCAGTTTGCATCCCTATCTATTAATGGGCCGTTCAGATAACGAAAT
GAGTGGCTCAGCGATTATTATTGATGGCTTAGCTATCACTACTTTTGATTCTAACGTCTTACCTATCAGCCAGTTACCTA
ATCTAAACGCCAGGGAGATTACATTACCTGGTTATCCGATTAAGATATTGATTTATCATAATAGTATAACGAAAAACGAT
ATTAGAATGACCCTGTTAGGTGGCCTATTACTTGCCGGCTTGGTGGGCATCTTGGCTTATTATATTTTAATCACCAAAAA
AAGTGCTGAAGCTGAAATTTTACGGGGCATTAGGCGCGGTGAGTTTTTCGTTGAATATCAACCGGTTTTTCGCTCACATA
ATCAGACAATATCAGGTTTAGAAGCCCTTATCCGTTGGCAACACCCGACTGAAGGGCGGATTTCGCCCGATATCTTCATT
CCTTATGCCGAAACTCAACACCTGATACAGCCGCTGACAACGCACTTGTTTGAGTTAATTATCAGAGATACCGCTCTTAT
GGTAAATCTGTTCCCGACGGGCGCTAAACTTGCCTTTAATATTTCACCGGCCCATCTTGCTGATGATGATTTTTGTCAGG
ACGTATCACGACTCTTGCAGCAATTAAATACCGATATTTTTACCCCCGTATTCGAAATTACTGAGCGAGGTATGGTGCAA
AAAGAGTTGGCCCTGAAGCAATTCGCATGGCTGCATTCGCAAGGGATTCAAATCGCTGTCGATGATTTTGGCACCGGCCA
TAGCGCCCTGATCTATTTAGAACGCTTTACCTTAGATTATATTAAAATTGATCGCGGCTTTATCAGCACGATAGGCGAAA
ATACGGTGACAACGCCGGTATTAGATTCGGTATTAATTCTGGCAAAAAAACTTAATATTGAAACTATCGCTGAGGGCATC
GAGACTGAGCAACAACTTCACTATTTAGCTAAACATGGTGTCAATTACTTGCAGGGTTATTTACTCAGTAAGCCGCTGTC
TGTTGAAGCTTTAGCTAAATTCTGTCATGAAAAGATGAGTAACAAAAACTTACTGGCTTAA

Upstream 100 bases:

>100_bases
TCACAGATAGCCGCAAACACATTAGTGTTGCTAGCACGGCTGCAACATCAAGTCATAGCGGTATAAATACTTTGCCAATC
ATACTGAGGAACGGCGTAAC

Downstream 100 bases:

>100_bases
TGTTTGCATTATCCCCCTGTAAGCTGGTAATTTCATTTGAGAAAATGATTATCTGCAGCTTCGCAGGAGATTGCCAACAA
TATGTTTTTACGCTTATTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MGSNSAFSRNILSRRHLVKKSILLALCFFICFVVITLSLLYRSSENKLTTQSGNIITYASHFLNEITTTMSQLIPLSTQS
CEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHTPVSTIYPKVNLSQPLDFKIQQGTPMMPNKPAIAVWLRQAG
RGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKND
IRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGLEALIRWQHPTEGRISPDIFI
PYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFNISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITERGMVQ
KELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGI
ETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA

Sequences:

>Translated_526_residues
MGSNSAFSRNILSRRHLVKKSILLALCFFICFVVITLSLLYRSSENKLTTQSGNIITYASHFLNEITTTMSQLIPLSTQS
CEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHTPVSTIYPKVNLSQPLDFKIQQGTPMMPNKPAIAVWLRQAG
RGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKND
IRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGLEALIRWQHPTEGRISPDIFI
PYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFNISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITERGMVQ
KELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGI
ETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA
>Mature_525_residues
GSNSAFSRNILSRRHLVKKSILLALCFFICFVVITLSLLYRSSENKLTTQSGNIITYASHFLNEITTTMSQLIPLSTQSC
EQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHTPVSTIYPKVNLSQPLDFKIQQGTPMMPNKPAIAVWLRQAGR
GDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKNDI
RMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGLEALIRWQHPTEGRISPDIFIP
YAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFNISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITERGMVQK
ELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGIE
TEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=503, Percent_Identity=41.5506958250497, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI87081980, Length=514, Percent_Identity=28.988326848249, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI87081845, Length=523, Percent_Identity=29.2543021032505, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786507, Length=227, Percent_Identity=34.8017621145374, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787541, Length=250, Percent_Identity=33.2, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87081743, Length=272, Percent_Identity=29.4117647058824, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790496, Length=257, Percent_Identity=28.0155642023346, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87081921, Length=245, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788849, Length=235, Percent_Identity=28.936170212766, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI87082096, Length=231, Percent_Identity=29.004329004329, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI226510982, Length=249, Percent_Identity=28.5140562248996, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787055, Length=252, Percent_Identity=31.7460317460317, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787410, Length=137, Percent_Identity=27.7372262773723, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58691; Mature: 58560

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSNSAFSRNILSRRHLVKKSILLALCFFICFVVITLSLLYRSSENKLTTQSGNIITYAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEHHH
HFLNEITTTMSQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHT
HHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
PVSTIYPKVNLSQPLDFKIQQGTPMMPNKPAIAVWLRQAGRGDTGILATMEFSLHPYLLM
CHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHEEHHCCCCCCCEEEEEEECCCCEEEE
GRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKND
ECCCCCCCCCEEEEECEEEEEECCCCEEHHHCCCCCCCEEECCCCCEEEEEEECCCCCCH
IRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEHHHHCCCCHHHHH
EALIRWQHPTEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFN
HHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEE
ISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITERGMVQKELALKQFAWLHSQGIQIAV
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEE
DDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGI
ECCCCCCEEEEEEEEHEEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
ETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA
HHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GSNSAFSRNILSRRHLVKKSILLALCFFICFVVITLSLLYRSSENKLTTQSGNIITYAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEHHH
HFLNEITTTMSQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHT
HHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
PVSTIYPKVNLSQPLDFKIQQGTPMMPNKPAIAVWLRQAGRGDTGILATMEFSLHPYLLM
CHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHEEHHCCCCCCCEEEEEEECCCCEEEE
GRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKND
ECCCCCCCCCEEEEECEEEEEECCCCEEHHHCCCCCCCEEECCCCCEEEEEEECCCCCCH
IRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEHHHHCCCCHHHHH
EALIRWQHPTEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFN
HHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEE
ISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITERGMVQKELALKQFAWLHSQGIQIAV
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEE
DDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGI
ECCCCCCEEEEEEEEHEEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
ETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA
HHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]