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The map label for this gene is ycbL [H]

Identifier: 170024877

GI number: 170024877

Start: 2913842

End: 2914489

Strand: Reverse

Name: ycbL [H]

Synonym: YPK_2652

Alternate gene names: 170024877

Gene position: 2914489-2913842 (Counterclockwise)

Preceding gene: 170024878

Following gene: 170024876

Centisome position: 62.15

GC content: 50.77

Gene sequence:

>648_bases
ATGAAATATCAAATTATTCCAGTCACGGCGTTTAGCCAGAACTGTACGTTAATCTGGTGTGAAGCGACGGGGCAGGCTGC
CTTAGTGGATCCCGGTGGTGAGGCCACTAAAATAATTGCTGAGGTTGAGCGTCAGGGGGTTACCGTCAGCCAGGTTCTGT
TGACTCATGGTCATTTAGATCATGTTGGCGCGGCCGCTGAAGTTGCTGCACATTTTCAGGTACCGATTTATGGCCCTGAA
AAAGAAGACACTTTCTGGTTGGAAGGCTTACCCGCACAGAGCCGAATGTTTGGGCTAAGTGAATGTGAGGCTTTTACCCC
GACCCGCTGGTTGGAAGAAGGCGATAAAATAACGGTTGGCGAAATAGAGTTATCTGTTTTGCATTGTCCGGGGCACACGC
CGGGGCATATTGTATTTATTGACCCGCAAGGCCGCCTGGCTCTGGTGGGGGATGTTATCTTCAAGGGGGGCGTGGGGCGC
AGTGATTTTCCGCGTGGCGACCATCAACAGTTAATTAACTCCATCCGCACTAAATTACTGCCGTTGGGCGATGATATAAC
GTTTATTCCCGGCCATGGGCCTATGTCTACATTGGGGCATGAGCGGCAGACAAATCCGTTTATTCGAGAAGAGCCGGCTA
TTTGGTGA

Upstream 100 bases:

>100_bases
TTTTGTGCATATTGATACCGGGCCAACACGGGCTTGGTAAAACAAATTTTTTAGCCAGTGCCTACGCTCCAGTTGGTAGT
CACATTGGGGTTGGAGCTTT

Downstream 100 bases:

>100_bases
CGGTCGTATTTGATAACGGTAATATTTGGTGACGGTGGTTAGCGTCATCAATATCATACATAAATGTTTAATAGCAAAAG
ATGAATGTTCAATAGCAAAA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKYQIIPVTAFSQNCTLIWCEATGQAALVDPGGEATKIIAEVERQGVTVSQVLLTHGHLDHVGAAAEVAAHFQVPIYGPE
KEDTFWLEGLPAQSRMFGLSECEAFTPTRWLEEGDKITVGEIELSVLHCPGHTPGHIVFIDPQGRLALVGDVIFKGGVGR
SDFPRGDHQQLINSIRTKLLPLGDDITFIPGHGPMSTLGHERQTNPFIREEPAIW

Sequences:

>Translated_215_residues
MKYQIIPVTAFSQNCTLIWCEATGQAALVDPGGEATKIIAEVERQGVTVSQVLLTHGHLDHVGAAAEVAAHFQVPIYGPE
KEDTFWLEGLPAQSRMFGLSECEAFTPTRWLEEGDKITVGEIELSVLHCPGHTPGHIVFIDPQGRLALVGDVIFKGGVGR
SDFPRGDHQQLINSIRTKLLPLGDDITFIPGHGPMSTLGHERQTNPFIREEPAIW
>Mature_215_residues
MKYQIIPVTAFSQNCTLIWCEATGQAALVDPGGEATKIIAEVERQGVTVSQVLLTHGHLDHVGAAAEVAAHFQVPIYGPE
KEDTFWLEGLPAQSRMFGLSECEAFTPTRWLEEGDKITVGEIELSVLHCPGHTPGHIVFIDPQGRLALVGDVIFKGGVGR
SDFPRGDHQQLINSIRTKLLPLGDDITFIPGHGPMSTLGHERQTNPFIREEPAIW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI116642887, Length=249, Percent_Identity=26.9076305220884, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI21703352, Length=249, Percent_Identity=26.9076305220884, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI41327741, Length=201, Percent_Identity=27.8606965174129, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787158, Length=215, Percent_Identity=70.6976744186046, Blast_Score=335, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI17538952, Length=195, Percent_Identity=24.6153846153846, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330176, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23507; Mature: 23507

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQIIPVTAFSQNCTLIWCEATGQAALVDPGGEATKIIAEVERQGVTVSQVLLTHGHLD
CCEEEEEEEEECCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHCCCHH
HVGAAAEVAAHFQVPIYGPEKEDTFWLEGLPAQSRMFGLSECEAFTPTRWLEEGDKITVG
HHCHHHHHHEEEEEEEECCCCCCEEEEECCCHHHHHCCCHHHCCCCCHHHHHCCCEEEEE
EIELSVLHCPGHTPGHIVFIDPQGRLALVGDVIFKGGVGRSDFPRGDHQQLINSIRTKLL
EEEEEEEECCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEE
PLGDDITFIPGHGPMSTLGHERQTNPFIREEPAIW
ECCCCEEEECCCCCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKYQIIPVTAFSQNCTLIWCEATGQAALVDPGGEATKIIAEVERQGVTVSQVLLTHGHLD
CCEEEEEEEEECCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHCCCHH
HVGAAAEVAAHFQVPIYGPEKEDTFWLEGLPAQSRMFGLSECEAFTPTRWLEEGDKITVG
HHCHHHHHHEEEEEEEECCCCCCEEEEECCCHHHHHCCCHHHCCCCCHHHHHCCCEEEEE
EIELSVLHCPGHTPGHIVFIDPQGRLALVGDVIFKGGVGRSDFPRGDHQQLINSIRTKLL
EEEEEEEECCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEE
PLGDDITFIPGHGPMSTLGHERQTNPFIREEPAIW
ECCCCEEEECCCCCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]