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The map label for this gene is ycgM [C]

Identifier: 170024734

GI number: 170024734

Start: 2744416

End: 2745258

Strand: Reverse

Name: ycgM [C]

Synonym: YPK_2509

Alternate gene names: 170024734

Gene position: 2745258-2744416 (Counterclockwise)

Preceding gene: 170024735

Following gene: 170024733

Centisome position: 58.54

GC content: 51.84

Gene sequence:

>843_bases
ATGAAACTATTACGTTATGGTCCCGTCGGCGAGGAGCGCCCGGCGTTACTTGATGAGTTGGGAGAGATTCGTGATCTCTC
GGCACATATCGAGGATATCAGTGGCAAATTTTTACTGCCTGCGACGCTGTACAAACTGCGTCAGTTGGATAGCGCCAGTT
TGCCCCTCGTTCGGGGTGAACAACGCCTTGGTGCTTGCGTGGGTCATGTCGGTAAGTTTATCTGTATTGGTCTGAACTAC
GCCGATCATGCTGCTGAAACGGGGGCAGAAATCCCGCAAGAACCGGTGATCTTCAATAAGTGGACCAGCGCCATTATTGG
CCCGAATGACGATATAGAAATCCCGCGTAACTCAGTGAAAACCGATTGGGAAGTTGAACTGGGGGTGGTGATTGGCACAG
GCGGGCGATATATCGGTGAGGCCAACGCCATGTCTCACGTTGCTGGCTATTGCGTGGTCAACGATATTTCCGAACGTGAG
TTCCAGCTAGAGCATGGCGGTACCTGGGATAAAGGGAAGGGTTGCGATACCTTCGGGCCGATTGGACCGTGGTTAGTGAC
CCGCGATGAAATACCCGATCCACATCAGCTAGGGTTGTGGTTAGACGTTGATGGCAGGCGCTATCAGAACGGCAGTACCC
GCACCATGATTTTCAAAATCCCGCAAATAATCAGTTATCTAAGCCGCTTTATGAGTTTGCAATCCGGGGATGTCATTTCT
ACCGGTACCCCACCTGGCGTGGGTCTTGGGCAAAAACCGCCCGTCTATTTACATGCAGGGCAGATAATGCGTTTGGGTAT
CGAAGGTCTGGGAGAACAGTGCCAGAAAACGATACAAGCGTAG

Upstream 100 bases:

>100_bases
GCGCTTACACCACCGGCACGATACATATTATCGACGGAGGCTGGAGCAATTAATACTTAGCGACCGTCATGGGTATTCAG
TCAGTTCTGAGGAGAACGAC

Downstream 100 bases:

>100_bases
TACTCATCTTTCGCGAACGGAGAGGTTAACCATGACAATAATCACTGCATTACGCACTGAGGATGTACGTTTTCCCACCT
CGTTGGAATTGGATGGTTCG

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICIGLNY
ADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSHVAGYCVVNDISERE
FQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA

Sequences:

>Translated_280_residues
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICIGLNY
ADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSHVAGYCVVNDISERE
FQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
>Mature_280_residues
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICIGLNY
ADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSHVAGYCVVNDISERE
FQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=240, Percent_Identity=44.5833333333333, Blast_Score=218, Evalue=5e-57,
Organism=Homo sapiens, GI40786394, Length=240, Percent_Identity=43.3333333333333, Blast_Score=207, Evalue=6e-54,
Organism=Homo sapiens, GI215422413, Length=179, Percent_Identity=41.8994413407821, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI66348062, Length=179, Percent_Identity=41.8994413407821, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI13654274, Length=179, Percent_Identity=41.8994413407821, Blast_Score=141, Evalue=7e-34,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=37.9120879120879, Blast_Score=128, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=199, Percent_Identity=36.6834170854271, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324161, Length=216, Percent_Identity=30.5555555555556, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28572127, Length=209, Percent_Identity=44.4976076555024, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=37.7450980392157, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24663695, Length=210, Percent_Identity=35.7142857142857, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30632; Mature: 30632

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGE
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCEECH
QRLGACVGHVGKFICIGLNYADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVK
HHHHHHHHHHHCEEEEECCCHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCC
TDWEVELGVVIGTGGRYIGEANAMSHVAGYCVVNDISEREFQLEHGGTWDKGKGCDTFGP
CCEEEEEEEEEECCCCEECCHHHHHHHHHEEEEECCCCCEEEECCCCCCCCCCCCCCCCC
IGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
CCCEEEECCCCCCHHHEEEEEECCCCEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEE
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
CCCCCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGE
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCEECH
QRLGACVGHVGKFICIGLNYADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVK
HHHHHHHHHHHCEEEEECCCHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCC
TDWEVELGVVIGTGGRYIGEANAMSHVAGYCVVNDISEREFQLEHGGTWDKGKGCDTFGP
CCEEEEEEEEEECCCCEECCHHHHHHHHHEEEEECCCCCEEEECCCCCCCCCCCCCCCCC
IGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
CCCEEEECCCCCCHHHEEEEEECCCCEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEE
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
CCCCCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA