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The map label for this gene is mtfA

Identifier: 170024715

GI number: 170024715

Start: 2721682

End: 2722494

Strand: Direct

Name: mtfA

Synonym: YPK_2490

Alternate gene names: 170024715

Gene position: 2721682-2722494 (Clockwise)

Preceding gene: 170024714

Following gene: 170024717

Centisome position: 58.04

GC content: 48.83

Gene sequence:

>813_bases
ATGATTAAATGGCTGTGGAAAGCAAATAAACCGCAAGCGGAGATGCTTGCGCAATGGCATGAGGCACTGAATATTCCTTT
GCTGGCTCCATTAAACGAACCAGAACAGCAACGGTTGGTTTCGGTGGCCAGTCAATTATTACAACAAAAGCGCTTCATCC
CCCTACAAGGCTTGATATTAACCCCATTGATGCAAGCACGCCTCGCTTTGCTATTCGCACTGCCGGTTATGGAGCTAGGT
GCCAAATGGTTAGATGGCTTTCACGAAGTCCTTATTTACCCTTCTCCCTTTATTGTCGCGGAGGACTGGCAAGATGACCT
TGGGTTGGTTCATTCAGGCCAAAGCGTACAGTCTGGCCAGAGCTGGGAACAAGGACCTATCGTCCTGAACTGGCAAGATA
TTCAAGATTCATTCGATTTATCTGGCTTTAATCTGGTGATCCATGAAGCTGCCCATAAATTGGATATGCGTAATGGGGGT
CATTCAAATGGCGTGCCCCCCATTGCGATGCGTGATGTGGCGGTATGGGAGCATGATCTACACCACGCCATGGATAATAT
CCAAGACGAGATTGATATGGTGGGTGTGGAAGGTGCCAGTATGGATGCCTATGCAGCCAGCAATCCAGCAGAATGTTTTG
CCGTATTATCAGAATACTTTTTCAGTGCCCCAGAGCTGCTGGAGGGCCGTTTCCCGGCAGTCTATCAACATTTTTGCCGG
TTCTACCGTCAAGATCCATTAGCTCGACTAAAACGCTGGGAAAACTCGCTGGCAGACAATCCGCCTCCCGAGAATACTCA
CTCGCACCGTTAG

Upstream 100 bases:

>100_bases
TCTCCATAATAACAGTTGCCATCATGTCTACTTTTACGGCATGTTGACTACAATACTCCCCTGCTTTAGACGTTAGAATG
ATCACTTTGCGAGCAACCTG

Downstream 100 bases:

>100_bases
CGATTAGCTTATTCTCCACACCTCAAAATATGCGTTAATCATAAAAACCTTGGGCTGGCGCTACGTTGTTGCGATTTACC
CTCTATTTGTTCAGATGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: Mlc titration factor A

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MIKWLWKANKPQAEMLAQWHEALNIPLLAPLNEPEQQRLVSVASQLLQQKRFIPLQGLILTPLMQARLALLFALPVMELG
AKWLDGFHEVLIYPSPFIVAEDWQDDLGLVHSGQSVQSGQSWEQGPIVLNWQDIQDSFDLSGFNLVIHEAAHKLDMRNGG
HSNGVPPIAMRDVAVWEHDLHHAMDNIQDEIDMVGVEGASMDAYAASNPAECFAVLSEYFFSAPELLEGRFPAVYQHFCR
FYRQDPLARLKRWENSLADNPPPENTHSHR

Sequences:

>Translated_270_residues
MIKWLWKANKPQAEMLAQWHEALNIPLLAPLNEPEQQRLVSVASQLLQQKRFIPLQGLILTPLMQARLALLFALPVMELG
AKWLDGFHEVLIYPSPFIVAEDWQDDLGLVHSGQSVQSGQSWEQGPIVLNWQDIQDSFDLSGFNLVIHEAAHKLDMRNGG
HSNGVPPIAMRDVAVWEHDLHHAMDNIQDEIDMVGVEGASMDAYAASNPAECFAVLSEYFFSAPELLEGRFPAVYQHFCR
FYRQDPLARLKRWENSLADNPPPENTHSHR
>Mature_270_residues
MIKWLWKANKPQAEMLAQWHEALNIPLLAPLNEPEQQRLVSVASQLLQQKRFIPLQGLILTPLMQARLALLFALPVMELG
AKWLDGFHEVLIYPSPFIVAEDWQDDLGLVHSGQSVQSGQSWEQGPIVLNWQDIQDSFDLSGFNLVIHEAAHKLDMRNGG
HSNGVPPIAMRDVAVWEHDLHHAMDNIQDEIDMVGVEGASMDAYAASNPAECFAVLSEYFFSAPELLEGRFPAVYQHFCR
FYRQDPLARLKRWENSLADNPPPENTHSHR

Specific function: Involved in the regulation of ptsG expression by binding and inactivating mlc

COG id: COG3228

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtfA family

Homologues:

Organism=Escherichia coli, GI87082014, Length=267, Percent_Identity=62.9213483146067, Blast_Score=350, Evalue=8e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTFA_YERP3 (A7FJD3)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401361.1
- STRING:   A7FJD3
- GeneID:   5386290
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2392
- eggNOG:   COG3228
- HOGENOM:   HBG429988
- OMA:   YFFSAPD
- ProtClustDB:   PRK15410
- BioCyc:   YPSE349747:YPSIP31758_2392-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01593
- InterPro:   IPR010384

Pfam domain/function: PF06167 DUF980

EC number: NA

Molecular weight: Translated: 30659; Mature: 30659

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKWLWKANKPQAEMLAQWHEALNIPLLAPLNEPEQQRLVSVASQLLQQKRFIPLQGLIL
CCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
TPLMQARLALLFALPVMELGAKWLDGFHEVLIYPSPFIVAEDWQDDLGLVHSGQSVQSGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHCCCCCCCCCC
SWEQGPIVLNWQDIQDSFDLSGFNLVIHEAAHKLDMRNGGHSNGVPPIAMRDVAVWEHDL
CCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
HHAMDNIQDEIDMVGVEGASMDAYAASNPAECFAVLSEYFFSAPELLEGRFPAVYQHFCR
HHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHH
FYRQDPLARLKRWENSLADNPPPENTHSHR
HHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MIKWLWKANKPQAEMLAQWHEALNIPLLAPLNEPEQQRLVSVASQLLQQKRFIPLQGLIL
CCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
TPLMQARLALLFALPVMELGAKWLDGFHEVLIYPSPFIVAEDWQDDLGLVHSGQSVQSGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHCCCCCCCCCC
SWEQGPIVLNWQDIQDSFDLSGFNLVIHEAAHKLDMRNGGHSNGVPPIAMRDVAVWEHDL
CCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
HHAMDNIQDEIDMVGVEGASMDAYAASNPAECFAVLSEYFFSAPELLEGRFPAVYQHFCR
HHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHH
FYRQDPLARLKRWENSLADNPPPENTHSHR
HHCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA