Click here to switch to the map view.

The map label for this gene is fliI [H]

Identifier: 170024619

GI number: 170024619

Start: 2628900

End: 2630318

Strand: Direct

Name: fliI [H]

Synonym: YPK_2394

Alternate gene names: 170024619

Gene position: 2628900-2630318 (Clockwise)

Preceding gene: 170024618

Following gene: 170024620

Centisome position: 56.06

GC content: 54.9

Gene sequence:

>1419_bases
ATGCCCCCCCGCCTCAGCCGCTGGCTTACCTCTTTAGATAAATTCGAAGAGCGTATCAGCCAAACGACAACAATCCGCCG
TTATGGCCGCTTGACCCGCGCCACCGGTTTAGTGCTGGAAGCCACTGGTCTGCAATTGCCGTTAGGGGCGACCTGTCTGA
TTGAGCGCCATAATGGCGGTGAAGTGCAGGAAGTCGAAAGCGAAGTGGTTGGTTTTAACGGTCAGCATCTGTTTCTTATG
CCTTTGGAAGATGTGGAAGGTATCGTCCCCGGTGCCAGAGTGTATGCCCGAGTCACCACCAGCGGCACGTCTGCCAGTAA
ACAGTCAATTTCTAGTAAACAATCAATTCCCAGTAAACAATCATTCGCCAGTAAACAATTACCCCTTGGCCCCGAGTTAT
TGGGCCGGGTATTGGATGGCAGTGCCAAACCGCTTGATGGCTTACCGGCACCTGAAACCGGTTATCGTGCACCACTGATT
ACACCACCGATAAACCCTTTGCAACGCACCGCCATTGTCCAAGTCTTGGATGTGGGCGTGCGTACCATTAACGCCTTGTT
GACGGTCGGGCGCGGCCAGCGGATGGGGCTGTTTGCTGGCTCTGGGGTTGGCAAAAGCGTACTGCTCGGCATGATGGCCC
GTTACACACAGGCTGACGTGATCGTGGTTGGGCTGATTGGTGAGCGTGGCCGTGAAGTCAAAGATTTTATCGAAAATATT
CTCGGGGCTGAAGGCCGTGCCCGTTCGGTGGTTATCGCCGCGCCAGCCGATGTGTCACCGTTGCTGCGTATGCAAGGTGC
CGCCTATGCCACCCGTATTGCCGAAGATTTCCGCGATCGTGGTCAGCATGTGTTGCTAATTATGGACTCCCTAACCCGCT
ATGCCATGGCGCAACGTGAAATCGCGCTGGCTATCGGCGAGCCTCCCGCGACCAAAGGTTATCCGCCCTCCGTCTTCGCC
AAATTACCGGCACTGGTTGAACGGGCGGGTAACGGTGTTTCAGGCGGCGGCTCCATTACCGCATTTTATACCGTCCTCAC
CGAAGGTGATGATCAGCAAGATCCTATTGCTGACTCTGCGCGCGCCATCCTCGATGGCCATGTGGTGCTATCTCGCCGCT
TGGCTGAATCCGGTCACTATCCGGCTATCGATATCGAAGCCTCTATCAGCCGTGCCATGACCTCGTTAATCGATGACGAC
CATTACAGCCGGGTGCGCCAGTTTAAACAACTGTTTGCCAGTTATCAGCGTAACCGCGATTTGGTCAGTGTCGGGGCTTA
TGCTGCGGGCAGTGATCCCTTATTGGACAAAGCGATTGCCCTGTACCCGCAGATGGAGGCTTTCTTGCAGCAAGGCATGT
TTGAGCGCAGCAGTTTTGACGATGCCTGCCAGCATTTGAAGGGTTTATTTCCCGGCTAA

Upstream 100 bases:

>100_bases
CTGGCGGCTGTAAAGTCAGCGCGGAAGAAGGCGATTTGGATGCCAGTCTGGCGACCCGTTGGCATGAACTGTGCCGTCTG
GCCGCGCCGGGGGAACTGTG

Downstream 100 bases:

>100_bases
GACGTTATTAAGGCTGAGCAGCCGGAAAGGATGACGCAAATCGCCGTGTCGCCCCTGTAACCAATGAGGAATTCGATGAA
AAGTCAGTCACCTCTCGTCA

Product: flagellum-specific ATP synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MPPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGGEVQEVESEVVGFNGQHLFLM
PLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLI
TPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENI
LGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFA
KLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDD
HYSRVRQFKQLFASYQRNRDLVSVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFDDACQHLKGLFPG

Sequences:

>Translated_472_residues
MPPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGGEVQEVESEVVGFNGQHLFLM
PLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLI
TPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENI
LGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFA
KLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDD
HYSRVRQFKQLFASYQRNRDLVSVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFDDACQHLKGLFPG
>Mature_471_residues
PPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGGEVQEVESEVVGFNGQHLFLMP
LEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLIT
PPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENIL
GAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAK
LPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDDH
YSRVRQFKQLFASYQRNRDLVSVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFDDACQHLKGLFPG

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage [

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=316, Percent_Identity=28.7974683544304, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI50345984, Length=356, Percent_Identity=26.9662921348315, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI4757810, Length=356, Percent_Identity=26.9662921348315, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI19913428, Length=415, Percent_Identity=27.4698795180723, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI19913426, Length=413, Percent_Identity=27.6029055690073, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI19913424, Length=240, Percent_Identity=30.4166666666667, Blast_Score=109, Evalue=5e-24,
Organism=Escherichia coli, GI1788251, Length=459, Percent_Identity=80.1742919389978, Blast_Score=716, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=366, Percent_Identity=28.4153005464481, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790172, Length=284, Percent_Identity=28.169014084507, Blast_Score=101, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=312, Percent_Identity=28.525641025641, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=374, Percent_Identity=28.6096256684492, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71988080, Length=354, Percent_Identity=25.9887005649718, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=356, Percent_Identity=26.9662921348315, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=370, Percent_Identity=25.6756756756757, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=243, Percent_Identity=31.2757201646091, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988074, Length=344, Percent_Identity=25.5813953488372, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322581, Length=309, Percent_Identity=29.126213592233, Blast_Score=136, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6319370, Length=346, Percent_Identity=27.1676300578035, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6319603, Length=384, Percent_Identity=28.6458333333333, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6320016, Length=274, Percent_Identity=29.1970802919708, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24638766, Length=311, Percent_Identity=28.6173633440514, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24658560, Length=369, Percent_Identity=27.10027100271, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574560, Length=338, Percent_Identity=27.810650887574, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281361666, Length=416, Percent_Identity=27.1634615384615, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646341, Length=416, Percent_Identity=27.1634615384615, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17136796, Length=416, Percent_Identity=27.1634615384615, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24583988, Length=314, Percent_Identity=28.6624203821656, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583986, Length=314, Percent_Identity=28.6624203821656, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583984, Length=314, Percent_Identity=28.6624203821656, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI20129479, Length=314, Percent_Identity=28.343949044586, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24583992, Length=317, Percent_Identity=28.0757097791798, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005714
- InterPro:   IPR020005 [H]

Pfam domain/function: PF00006 ATP-synt_ab [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50897; Mature: 50766

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCC
EVQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQ
CHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHH
SFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLITPPINPLQRTAIVQVLDVGV
HHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENI
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
LGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQRE
HCCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
IALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSA
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHH
RAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDDHYSRVRQFKQLFASYQRNRD
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
LVSVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFDDACQHLKGLFPG
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
PPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCC
EVQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQ
CHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHH
SFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLITPPINPLQRTAIVQVLDVGV
HHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENI
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
LGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQRE
HCCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
IALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSA
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHH
RAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDDHYSRVRQFKQLFASYQRNRD
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
LVSVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFDDACQHLKGLFPG
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]