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The map label for this gene is sirB2 [H]

Identifier: 170024408

GI number: 170024408

Start: 2416424

End: 2416825

Strand: Reverse

Name: sirB2 [H]

Synonym: YPK_2177

Alternate gene names: 170024408

Gene position: 2416825-2416424 (Counterclockwise)

Preceding gene: 170024409

Following gene: 170024407

Centisome position: 51.54

GC content: 43.28

Gene sequence:

>402_bases
ATGTGGGTTGATTACATCGCCATGAAATATTTGCATTTACTCACCGTGGTGATCAGCATTACTCTGTTTGTACTACGTTT
CTTCTGGAAATGTCGCGGCTCAGCGATGCTTGAAAAGCGTTGGGTAAAGATAACGCCGCACATCAATGATACGCTGCTGT
TTATCAGTGGTATTGTGCTGATATTGATTACTGGATTCTATCCATTCAGTCCGCAGGGAACATGGCTGACTGAGAAGCTG
TTTGGCGTTATTATCTACATCCTGCTTGGCTATGTTGCATTAGGTAAGCGAACTCGCAGCCAGAATATTCGCTGGTTTGC
CTTTATACTCGCACTGGGTTGCCTGTATCTAATTGTAAAACTGGCAACAACTAAATTACCACTGCTGATGGGATATCTAT
GA

Upstream 100 bases:

>100_bases
TAATGACCGGGTGACATTGGGGCAATGGTCCGTGTAACCACGCGCAGCTAATAGCGCTGCAACATCAAGTAAAAAGAGAT
AAAACAAGGAATCGATAGTC

Downstream 100 bases:

>100_bases
GTAGCATTGCTGATTTCGAATTTAATAACGCGTCCCTGTGTGATGGGGTGTTACTGGTTACCCAAGAGATTCGACAGACT
TTTCCGCTGGCTGATGTCCG

Product: invasion gene expression up-regulator SirB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MWVDYIAMKYLHLLTVVISITLFVLRFFWKCRGSAMLEKRWVKITPHINDTLLFISGIVLILITGFYPFSPQGTWLTEKL
FGVIIYILLGYVALGKRTRSQNIRWFAFILALGCLYLIVKLATTKLPLLMGYL

Sequences:

>Translated_133_residues
MWVDYIAMKYLHLLTVVISITLFVLRFFWKCRGSAMLEKRWVKITPHINDTLLFISGIVLILITGFYPFSPQGTWLTEKL
FGVIIYILLGYVALGKRTRSQNIRWFAFILALGCLYLIVKLATTKLPLLMGYL
>Mature_133_residues
MWVDYIAMKYLHLLTVVISITLFVLRFFWKCRGSAMLEKRWVKITPHINDTLLFISGIVLILITGFYPFSPQGTWLTEKL
FGVIIYILLGYVALGKRTRSQNIRWFAFILALGCLYLIVKLATTKLPLLMGYL

Specific function: Not essential for the expression of the invasive phenotype. Required for maximal expression of sirC [H]

COG id: COG3094

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787464, Length=120, Percent_Identity=50.8333333333333, Blast_Score=114, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007360 [H]

Pfam domain/function: PF04247 SirB [H]

EC number: NA

Molecular weight: Translated: 15437; Mature: 15437

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWVDYIAMKYLHLLTVVISITLFVLRFFWKCRGSAMLEKRWVKITPHINDTLLFISGIVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEECCCCCHHHHHHHHHHH
ILITGFYPFSPQGTWLTEKLFGVIIYILLGYVALGKRTRSQNIRWFAFILALGCLYLIVK
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHH
LATTKLPLLMGYL
HHHHHHHHHHCCC
>Mature Secondary Structure
MWVDYIAMKYLHLLTVVISITLFVLRFFWKCRGSAMLEKRWVKITPHINDTLLFISGIVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEECCCCCHHHHHHHHHHH
ILITGFYPFSPQGTWLTEKLFGVIIYILLGYVALGKRTRSQNIRWFAFILALGCLYLIVK
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHH
LATTKLPLLMGYL
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]