Click here to switch to the map view.

The map label for this gene is mlc [C]

Identifier: 170024398

GI number: 170024398

Start: 2404312

End: 2405424

Strand: Reverse

Name: mlc [C]

Synonym: YPK_2166

Alternate gene names: 170024398

Gene position: 2405424-2404312 (Counterclockwise)

Preceding gene: 170024399

Following gene: 170024397

Centisome position: 51.29

GC content: 55.35

Gene sequence:

>1113_bases
ATGAATATCCGACCTGAACGGCTTGAACTGCGCGGATCACAGCGCTTACTGCTGGAACTGATCCGCCGTCATGCGCCCGT
CACACGTGCGGAGTTAGCGCGCTTGTCGAACCTGACCGCGGGCGCGATCACCCAACAGTGCCGGGAATTAATCTTTGCCG
GTTTGGTGGTGGAAGGGGAACGCAATACCGGGCAGCGTGGTCAGCCATCGCTGCCGTTGCGTCTCAACCCTGGTGGTGGT
TGCGCTATTGGTTTGTCGTTCAGCCCCGGTTTTATCGATATGACCGTGGTCGATCTCAGTGGCCGCCAGTTATTATCGGT
TGCCGAGCCTCATCAGGAAAATCAGCCGCTGACTGCGACGCTTTGCCAAATCAAAACGCTGGTCGAACAGACGCTGAAGA
AACGCCAGCTACAGCACGCACGTATTATCGGCATTGGCTATGCGGTACCAGGTTTTCTTAAGGCTGATGGGCACAAACGC
CATTGTGTGCCGTGGCTGCATACTTGGCGAGAAGCGGACCTCCAGCAGGTGTTTGCCGATAATCTGCCGTGGCCTACCCG
GGTGGAGAACAATGCCAATGCTTCAGCTATCGGCGAACTGTACAGCGGCGAGTGGAACAACTACAGCGATCTGACTTTTA
TCGACCTTGGCTATGGCATCGGCGCGGGTGTGATCTCTGGGCATAAGTTGTTGCGCGGTGGTTTTTTCAATGCTGGGGAA
GTCGGCATGGCGTTCCCTTCAGGTACACCGCGTCCGTCATATAAAGATTTACTGGCTACGCTGGAGCGTGAGGGATTTAG
CGAAACGCAACTGCCAGTGCTGAGCGCTGGGCGGCATCCGGTGTTGGAAAAGTGGTTTGAACGCTGCTGTGATCAAGTGC
AACAAACGGTGTTTGGTTGTGTGCAATGGGTTGACCCACAACTGATTGTACTGGGGGGGGCTATGCCGAAGCCCATCATC
AGCCGCCTTGTGCAGGAAATAAGCCAACGCCTGAATACCTGCCTGGATCCTGAGCGTCCAAAAGTAACCTTAGCCGCTTC
GTCAATGGGGGCGGAAAGCGCTTCACGTGGCGCGGCGATGATCCCTCTGTATCAGGTGATTAATGAGGATTAA

Upstream 100 bases:

>100_bases
CGTGAAGGGCTGATCGACATGCTTAGCCACGATGATATTCCATATCTTCAGGCGCTAATTGAAGAAGCGGGTCTGCGCTG
GGATTAATATTAAGGACACC

Downstream 100 bases:

>100_bases
GGGGGAGATATACGGCCCTAAAAATTCTGTGAAGCTGAAGGATTGGACACAATACGATTAGAGCCTGTAAGTGACTGATG
CAAGCAACCTACTGGTATAA

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQCRELIFAGLVVEGERNTGQRGQPSLPLRLNPGGG
CAIGLSFSPGFIDMTVVDLSGRQLLSVAEPHQENQPLTATLCQIKTLVEQTLKKRQLQHARIIGIGYAVPGFLKADGHKR
HCVPWLHTWREADLQQVFADNLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVISGHKLLRGGFFNAGE
VGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWFERCCDQVQQTVFGCVQWVDPQLIVLGGAMPKPII
SRLVQEISQRLNTCLDPERPKVTLAASSMGAESASRGAAMIPLYQVINED

Sequences:

>Translated_370_residues
MNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQCRELIFAGLVVEGERNTGQRGQPSLPLRLNPGGG
CAIGLSFSPGFIDMTVVDLSGRQLLSVAEPHQENQPLTATLCQIKTLVEQTLKKRQLQHARIIGIGYAVPGFLKADGHKR
HCVPWLHTWREADLQQVFADNLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVISGHKLLRGGFFNAGE
VGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWFERCCDQVQQTVFGCVQWVDPQLIVLGGAMPKPII
SRLVQEISQRLNTCLDPERPKVTLAASSMGAESASRGAAMIPLYQVINED
>Mature_370_residues
MNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQCRELIFAGLVVEGERNTGQRGQPSLPLRLNPGGG
CAIGLSFSPGFIDMTVVDLSGRQLLSVAEPHQENQPLTATLCQIKTLVEQTLKKRQLQHARIIGIGYAVPGFLKADGHKR
HCVPWLHTWREADLQQVFADNLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVISGHKLLRGGFFNAGE
VGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWFERCCDQVQQTVFGCVQWVDPQLIVLGGAMPKPII
SRLVQEISQRLNTCLDPERPKVTLAASSMGAESASRGAAMIPLYQVINED

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1787878, Length=228, Percent_Identity=27.1929824561404, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786891, Length=230, Percent_Identity=25.2173913043478, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 40689; Mature: 40689

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQCRELIFAGLVVEGE
CCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEECC
RNTGQRGQPSLPLRLNPGGGCAIGLSFSPGFIDMTVVDLSGRQLLSVAEPHQENQPLTAT
CCCCCCCCCCCCEEECCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHCCCCCCCCHHHH
LCQIKTLVEQTLKKRQLQHARIIGIGYAVPGFLKADGHKRHCVPWLHTWREADLQQVFAD
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHC
NLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVISGHKLLRGGFFNAGE
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
VGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWFERCCDQVQQTVFGC
CCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VQWVDPQLIVLGGAMPKPIISRLVQEISQRLNTCLDPERPKVTLAASSMGAESASRGAAM
HHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHCCCCHH
IPLYQVINED
HHHHHHHCCC
>Mature Secondary Structure
MNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQCRELIFAGLVVEGE
CCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEECC
RNTGQRGQPSLPLRLNPGGGCAIGLSFSPGFIDMTVVDLSGRQLLSVAEPHQENQPLTAT
CCCCCCCCCCCCEEECCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHCCCCCCCCHHHH
LCQIKTLVEQTLKKRQLQHARIIGIGYAVPGFLKADGHKRHCVPWLHTWREADLQQVFAD
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHC
NLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVISGHKLLRGGFFNAGE
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
VGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWFERCCDQVQQTVFGC
CCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VQWVDPQLIVLGGAMPKPIISRLVQEISQRLNTCLDPERPKVTLAASSMGAESASRGAAM
HHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHCCCCHH
IPLYQVINED
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]