Click here to switch to the map view.

The map label for this gene is znuA [H]

Identifier: 170024374

GI number: 170024374

Start: 2371491

End: 2372447

Strand: Reverse

Name: znuA [H]

Synonym: YPK_2140

Alternate gene names: 170024374

Gene position: 2372447-2371491 (Counterclockwise)

Preceding gene: 170024377

Following gene: 170024373

Centisome position: 50.59

GC content: 44.62

Gene sequence:

>957_bases
ATGTTACATAAAAATAAATGGCTAAAACAGGCAATGCTCGCCAGCGCACTTTTACTGGCAAATCCCTTTAATCTGGCTTC
GGCGGCCGTTGTTACATCAATACGCCCGCTAGGTTTTATTGCTGCCGCCATTGCAGATGGGGTGCTGCCAACCGAGGTTT
TATTACCTGATGGCGCATCTCCCCACGATTATGCGCTTCGTCCATCGGATGTCCAGCGGTTACGTAGCGCCGAATTGGTT
ATTTGGGTCGGGCCGGAAATGGAAGCATTTCTATCAAAACCATTAACGCAAGTCGCTGAAAATAAACAGATCTCTTTATC
ACAGTTACCTTCTGTTACACCATTGTTGATGAAGAGTGATGAACATGATGAGGCTGAAGAGGGCGAGAGTGGACATCATC
ATGATCATGCTAAAGATAATCCGACTGATGACCACCATCACGGTGAGTATAACATGCATATTTGGCTGTCACCGGCCATC
GCTAAACAGGCTGCAATTGCTATACACGACAGATTATTGGAACTTACGCCACAAAATAAGGACAAATTAGATGCGAACCT
GCGTCGATTCGAGTATCAACTAGCGCAAAATGAAAAAAATATTGTTACTATGCTTAAGCCTGTCCAAGGTAAGGGATATT
TTGTTTTTCATGACGCCTATGGCTACTTTGAAAATCACTTTGGCTTGAGTCCATTAGGGCATTTTACAGTCAATCCTGAA
ATACAACCTGGTGCGCAGCGTTTACATCAAATTCGAACACAGTTGGTTGAGCATAAGGCGGTATGCGTTTTTGCTGAACC
ACAATTCAGGCCAGCGGTCATTAATGCTGTTGCCAAGGGAACTAACGTGCGTTCTGGCACACTGGATCCTTTAGGGAGCG
GTATAGTATTGGACAAGGACAGCTATGTGAACTTTTTGTCTCAGTTGTCGAACCAATATGTGAGCTGCCTGAAGTAA

Upstream 100 bases:

>100_bases
TATTAAGCGTTACCAATATGGGCATCATGATTATATTTGCAGAATCTAGTGAATGTTATAATATTACGCTTTACCCATCA
AAACGTCGAGAATTCGTATT

Downstream 100 bases:

>100_bases
GATTAAAAGGATACTCATAAGTGCAGCAGATAGTCAGAACTATCACTTTAGCATATAACAATCTTCCTCGACCCCATCGC
ATCATGTTGGGGTCGTTGAC

Product: high-affinity zinc transporter periplasmic component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGASPHDYALRPSDVQRLRSAELV
IWVGPEMEAFLSKPLTQVAENKQISLSQLPSVTPLLMKSDEHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAI
AKQAAIAIHDRLLELTPQNKDKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKDSYVNFLSQLSNQYVSCLK

Sequences:

>Translated_318_residues
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGASPHDYALRPSDVQRLRSAELV
IWVGPEMEAFLSKPLTQVAENKQISLSQLPSVTPLLMKSDEHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAI
AKQAAIAIHDRLLELTPQNKDKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKDSYVNFLSQLSNQYVSCLK
>Mature_318_residues
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGASPHDYALRPSDVQRLRSAELV
IWVGPEMEAFLSKPLTQVAENKQISLSQLPSVTPLLMKSDEHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAI
AKQAAIAIHDRLLELTPQNKDKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKDSYVNFLSQLSNQYVSCLK

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=293, Percent_Identity=64.8464163822526, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 35261; Mature: 35261

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGAS
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCC
PHDYALRPSDVQRLRSAELVIWVGPEMEAFLSKPLTQVAENKQISLSQLPSVTPLLMKSD
CCCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHCCCC
EHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAIAKQAAIAIHDRLLELTPQNK
CCCCHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCC
DKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCHHHHHCCCCCCCCCEEECCC
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKD
CCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCH
SYVNFLSQLSNQYVSCLK
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGAS
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCC
PHDYALRPSDVQRLRSAELVIWVGPEMEAFLSKPLTQVAENKQISLSQLPSVTPLLMKSD
CCCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHCCCC
EHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAIAKQAAIAIHDRLLELTPQNK
CCCCHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCC
DKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCHHHHHCCCCCCCCCEEECCC
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKD
CCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCH
SYVNFLSQLSNQYVSCLK
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]