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The map label for this gene is sohB [H]

Identifier: 170024271

GI number: 170024271

Start: 2267279

End: 2268325

Strand: Reverse

Name: sohB [H]

Synonym: YPK_2036

Alternate gene names: 170024271

Gene position: 2268325-2267279 (Counterclockwise)

Preceding gene: 170024274

Following gene: 170024269

Centisome position: 48.37

GC content: 48.33

Gene sequence:

>1047_bases
GTGGAGTTAATTTCTTTGTACGGGCTGTTTCTGGCTAAAGTGGTGACCATCGTGGTTGCGATTGGTGCAGTAGTGTTATT
GGTGGTCAGCCAGGGAATGAGAAGACAAGGGCAACGGGGGGAATTGAACCTGGTTGATCTGGGGGAACAATATAAAGAAA
CTCAGCGAGAAATGCGGCTGGCACGCATGAGCCATGCAGAACAAAAAGCCTGGGTTAAAGAATTTAAAAAGCAGGAAAAA
GCGGATCAAAAACTGAAGAAACAACGCGCAAAATCGGGTGCGGTGGCGGCAGTAAAACCATGTTTATATGTCATTGATTT
TAAAGGGAGCATTGGGGCGCAGGAGGTCTCTTCATTACGTGAAGAGATCTCTGCTATTTTGGCCGTTGCAACCGCGCAAG
ATGAAGTGTTGCTACGGCTGGAAAGTCCGGGCGGTGTGGTGCATGGCTATGGGTTGGCGGCTTCTCAATTAGCGCGCCTG
CGTCAGCGTGGGATCCGCCTGACGGTTGCGGTTGATAAAGTTGCCGCCAGTGGCGGTTATATGATGGCCTGTGTTGCTGA
CCGCATTATCTGTGCGCCTTTCGCCATTATTGGCTCCATTGGCGTGGTCGCTCAAATTCCGAATTTCCATCGCTTACTGA
AAAAGAACGACATTGACGTAGAACTGCATACCGCAGGTGAATTTAAACGCACACTGACGTTGTTTGGTGAGAATACGGAG
CAGGGGCGTGAAAAATTCCGTGAAGATTTAAATGAAACTCACCTGTTATTTAAACAATTCGTGCAGCAGCAACGTCCTTC
TTTAGATATTGATGCTGTCGCGACGGGCGAGCATTGGTTTGGTACGCAAGCCAAAGAGAAAGGTTTGGTTGATGCTATCG
GCACCAGTGATGATTTACTGATCGCTGAAATGGATAATCACGAAGTCATTGGCGTGCGTTATTCTCATCGTAAACGCCTA
ATAGAGCGTTTTATGGGGAGTGCAACCGAAAGTGTTGACAGCCTATTATTACGTTGGTGGCAGCGGGGTGAGAAGCCGCT
GCTATAA

Upstream 100 bases:

>100_bases
AGTGAAACCAATGCAATTTTTCATTTACGGGAGACGCCAGCTCAGTGGTTCGCTAGAATGCAGGTATCTCTCTAAAAACA
CATGAAGAAAGGCGGTATTT

Downstream 100 bases:

>100_bases
CCCATAGTAGCTTCTTAGTGATGGCAATAAATGCAGGGGGTAATCTGAACGGTACCCCCTGCTATTTGCTACCAACCCAG
CCGTTAACTGGCTGTGATAA

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MELISLYGLFLAKVVTIVVAIGAVVLLVVSQGMRRQGQRGELNLVDLGEQYKETQREMRLARMSHAEQKAWVKEFKKQEK
ADQKLKKQRAKSGAVAAVKPCLYVIDFKGSIGAQEVSSLREEISAILAVATAQDEVLLRLESPGGVVHGYGLAASQLARL
RQRGIRLTVAVDKVAASGGYMMACVADRIICAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
QGREKFREDLNETHLLFKQFVQQQRPSLDIDAVATGEHWFGTQAKEKGLVDAIGTSDDLLIAEMDNHEVIGVRYSHRKRL
IERFMGSATESVDSLLLRWWQRGEKPLL

Sequences:

>Translated_348_residues
MELISLYGLFLAKVVTIVVAIGAVVLLVVSQGMRRQGQRGELNLVDLGEQYKETQREMRLARMSHAEQKAWVKEFKKQEK
ADQKLKKQRAKSGAVAAVKPCLYVIDFKGSIGAQEVSSLREEISAILAVATAQDEVLLRLESPGGVVHGYGLAASQLARL
RQRGIRLTVAVDKVAASGGYMMACVADRIICAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
QGREKFREDLNETHLLFKQFVQQQRPSLDIDAVATGEHWFGTQAKEKGLVDAIGTSDDLLIAEMDNHEVIGVRYSHRKRL
IERFMGSATESVDSLLLRWWQRGEKPLL
>Mature_348_residues
MELISLYGLFLAKVVTIVVAIGAVVLLVVSQGMRRQGQRGELNLVDLGEQYKETQREMRLARMSHAEQKAWVKEFKKQEK
ADQKLKKQRAKSGAVAAVKPCLYVIDFKGSIGAQEVSSLREEISAILAVATAQDEVLLRLESPGGVVHGYGLAASQLARL
RQRGIRLTVAVDKVAASGGYMMACVADRIICAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
QGREKFREDLNETHLLFKQFVQQQRPSLDIDAVATGEHWFGTQAKEKGLVDAIGTSDDLLIAEMDNHEVIGVRYSHRKRL
IERFMGSATESVDSLLLRWWQRGEKPLL

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=349, Percent_Identity=65.0429799426934, Blast_Score=436, Evalue=1e-124,
Organism=Escherichia coli, GI1788064, Length=168, Percent_Identity=29.7619047619048, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 38748; Mature: 38748

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELISLYGLFLAKVVTIVVAIGAVVLLVVSQGMRRQGQRGELNLVDLGEQYKETQREMRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHH
ARMSHAEQKAWVKEFKKQEKADQKLKKQRAKSGAVAAVKPCLYVIDFKGSIGAQEVSSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCEEEEEECCCCCCHHHHHHHH
EEISAILAVATAQDEVLLRLESPGGVVHGYGLAASQLARLRQRGIRLTVAVDKVAASGGY
HHHHHHHHHHCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCEEEEEEEHHHCCCCE
MMACVADRIICAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
EHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCHHHHHHEECCCCH
QGREKFREDLNETHLLFKQFVQQQRPSLDIDAVATGEHWFGTQAKEKGLVDAIGTSDDLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCCEECCCCCCEE
IAEMDNHEVIGVRYSHRKRLIERFMGSATESVDSLLLRWWQRGEKPLL
EEECCCCEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELISLYGLFLAKVVTIVVAIGAVVLLVVSQGMRRQGQRGELNLVDLGEQYKETQREMRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHH
ARMSHAEQKAWVKEFKKQEKADQKLKKQRAKSGAVAAVKPCLYVIDFKGSIGAQEVSSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCEEEEEECCCCCCHHHHHHHH
EEISAILAVATAQDEVLLRLESPGGVVHGYGLAASQLARLRQRGIRLTVAVDKVAASGGY
HHHHHHHHHHCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCEEEEEEEHHHCCCCE
MMACVADRIICAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
EHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCHHHHHHEECCCCH
QGREKFREDLNETHLLFKQFVQQQRPSLDIDAVATGEHWFGTQAKEKGLVDAIGTSDDLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCCEECCCCCCEE
IAEMDNHEVIGVRYSHRKRLIERFMGSATESVDSLLLRWWQRGEKPLL
EEECCCCEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]