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The map label for this gene is cfa [H]

Identifier: 170024097

GI number: 170024097

Start: 2065223

End: 2066374

Strand: Reverse

Name: cfa [H]

Synonym: YPK_1858

Alternate gene names: 170024097

Gene position: 2066374-2065223 (Counterclockwise)

Preceding gene: 170024098

Following gene: 170024095

Centisome position: 44.06

GC content: 46.44

Gene sequence:

>1152_bases
ATGAGTTCATCCTGTATAGAAGATCAGAGTGTTCAAGAAAGCCCATGGTTCCGCATTGTGCAAGACATGCTGAACCAAGC
TGATATTGAAATCAATGGTTCACGCCCTTTCGATATTCGGGTCAACAACCCAGACTTTTTTAAACGGGTGCTACAAGGAG
GATCTTTGGCATTAGGTGAGAGTTATATGGATGGCTGGTGGGAGTGCGATCGTCTGGATATATTCTTCCAGCGCGTTCTT
CAGGCGGGTCTGGAACATAAACTCCCACGCCATTTCAAAGATACTTTGCGTATCGCTGCCGCCCGTGTCATCAATTTACA
ATCAAAGAGAAGAGCCTGGATTGTTGGCAAAGAGCATTATGACTTAGGTAATGATCTCTTTACTCAAATACTTGACCCGA
ATATGCAATATTCTTGCGCCTACTGGAAAGAAGCCACCAGCCTTGAACAGGCGCAGGAACATAAACTGCAAATGATTTGC
GAGAAATTGCAATTAGCGCCAGGCATGAAGCTGTTGGATATCGGTTGTGGCTGGGGGGGGCTTGCTGCTTATGCCGCCAG
ACATTTCGGGGTGTCAGTCTCGGGTGTGACTATTTCTGTTGAACAACAAAAACTAGCACAACAGCGGTGTGAAGGCCTTG
ATGTCAGCATTTTATTGCAGGATTACCGTGACTTGAATGAGCAATTTGACCGCATTGTTTCTGTCGGCATGTTCGAACAT
GTGGGTCCCAAGAACTACTCCACTTATTTTAAGGTGGTAAACCGTAATTTAAAACCGGATGGATTGTTCTTGCTGCACAC
CATCGGCGCTAACCGCACCAATATGAACGTCGACCCCTGGATCAATAAATATATCTTCCCCAATGGTTGTCTGCCGTCAG
TACAACATATTGCTCAGGCTAGTGAACCGTATTTTGTCATGGAAGACTGGCATAATTTTGGCGCGGATTATGACCGAACA
TTGATGGCATGGTATGAGCGTTTCCAGGCAGCGTGGCCAAATCTGTCTGCGAATTACTCACAACGGTTTGAACGGATGTT
TAGCTATTATCTTAATGCCTGCGCGGGCGCATTTCGCGCCAGAGACATTCAGTTGTGGCAAGTACTATTCAGTCCAAATG
GTGTGAATGGGGGGATTCGCGTCCCTCGCTAA

Upstream 100 bases:

>100_bases
CGGATATCAGACACCAGGGTAACAAAACCTTATTGGTATGCATCTGCGTAGCTAACACTGAACCGCGGATCATAAGTCAG
AAGAAAGTGATGGAGAAGCT

Downstream 100 bases:

>100_bases
CCTCAGATAGGAGACAGGGGGATAAAAACCCCTGTCTTATTTTTTGTAGGTTATGACACCCGTACGACTTTTTCGTCCAC
TAACGCCGCGTTAGCCATAT

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSSSCIEDQSVQESPWFRIVQDMLNQADIEINGSRPFDIRVNNPDFFKRVLQGGSLALGESYMDGWWECDRLDIFFQRVL
QAGLEHKLPRHFKDTLRIAAARVINLQSKRRAWIVGKEHYDLGNDLFTQILDPNMQYSCAYWKEATSLEQAQEHKLQMIC
EKLQLAPGMKLLDIGCGWGGLAAYAARHFGVSVSGVTISVEQQKLAQQRCEGLDVSILLQDYRDLNEQFDRIVSVGMFEH
VGPKNYSTYFKVVNRNLKPDGLFLLHTIGANRTNMNVDPWINKYIFPNGCLPSVQHIAQASEPYFVMEDWHNFGADYDRT
LMAWYERFQAAWPNLSANYSQRFERMFSYYLNACAGAFRARDIQLWQVLFSPNGVNGGIRVPR

Sequences:

>Translated_383_residues
MSSSCIEDQSVQESPWFRIVQDMLNQADIEINGSRPFDIRVNNPDFFKRVLQGGSLALGESYMDGWWECDRLDIFFQRVL
QAGLEHKLPRHFKDTLRIAAARVINLQSKRRAWIVGKEHYDLGNDLFTQILDPNMQYSCAYWKEATSLEQAQEHKLQMIC
EKLQLAPGMKLLDIGCGWGGLAAYAARHFGVSVSGVTISVEQQKLAQQRCEGLDVSILLQDYRDLNEQFDRIVSVGMFEH
VGPKNYSTYFKVVNRNLKPDGLFLLHTIGANRTNMNVDPWINKYIFPNGCLPSVQHIAQASEPYFVMEDWHNFGADYDRT
LMAWYERFQAAWPNLSANYSQRFERMFSYYLNACAGAFRARDIQLWQVLFSPNGVNGGIRVPR
>Mature_382_residues
SSSCIEDQSVQESPWFRIVQDMLNQADIEINGSRPFDIRVNNPDFFKRVLQGGSLALGESYMDGWWECDRLDIFFQRVLQ
AGLEHKLPRHFKDTLRIAAARVINLQSKRRAWIVGKEHYDLGNDLFTQILDPNMQYSCAYWKEATSLEQAQEHKLQMICE
KLQLAPGMKLLDIGCGWGGLAAYAARHFGVSVSGVTISVEQQKLAQQRCEGLDVSILLQDYRDLNEQFDRIVSVGMFEHV
GPKNYSTYFKVVNRNLKPDGLFLLHTIGANRTNMNVDPWINKYIFPNGCLPSVQHIAQASEPYFVMEDWHNFGADYDRTL
MAWYERFQAAWPNLSANYSQRFERMFSYYLNACAGAFRARDIQLWQVLFSPNGVNGGIRVPR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=383, Percent_Identity=77.2845953002611, Blast_Score=640, Evalue=0.0,
Organism=Caenorhabditis elegans, GI133904226, Length=389, Percent_Identity=30.8483290488432, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 44108; Mature: 43976

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSCIEDQSVQESPWFRIVQDMLNQADIEINGSRPFDIRVNNPDFFKRVLQGGSLALGE
CCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCCEEEEECCHHHHHHHHCCCCEEECC
SYMDGWWECDRLDIFFQRVLQAGLEHKLPRHFKDTLRIAAARVINLQSKRRAWIVGKEHY
HHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHC
DLGNDLFTQILDPNMQYSCAYWKEATSLEQAQEHKLQMICEKLQLAPGMKLLDIGCGWGG
CCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHH
LAAYAARHFGVSVSGVTISVEQQKLAQQRCEGLDVSILLQDYRDLNEQFDRIVSVGMFEH
HHHHHHHHCCCEEECEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGPKNYSTYFKVVNRNLKPDGLFLLHTIGANRTNMNVDPWINKYIFPNGCLPSVQHIAQA
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHC
SEPYFVMEDWHNFGADYDRTLMAWYERFQAAWPNLSANYSQRFERMFSYYLNACAGAFRA
CCCEEEEECHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RDIQLWQVLFSPNGVNGGIRVPR
CHHHEEHEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SSSCIEDQSVQESPWFRIVQDMLNQADIEINGSRPFDIRVNNPDFFKRVLQGGSLALGE
CCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCCEEEEECCHHHHHHHHCCCCEEECC
SYMDGWWECDRLDIFFQRVLQAGLEHKLPRHFKDTLRIAAARVINLQSKRRAWIVGKEHY
HHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHC
DLGNDLFTQILDPNMQYSCAYWKEATSLEQAQEHKLQMICEKLQLAPGMKLLDIGCGWGG
CCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHH
LAAYAARHFGVSVSGVTISVEQQKLAQQRCEGLDVSILLQDYRDLNEQFDRIVSVGMFEH
HHHHHHHHCCCEEECEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGPKNYSTYFKVVNRNLKPDGLFLLHTIGANRTNMNVDPWINKYIFPNGCLPSVQHIAQA
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHC
SEPYFVMEDWHNFGADYDRTLMAWYERFQAAWPNLSANYSQRFERMFSYYLNACAGAFRA
CCCEEEEECHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RDIQLWQVLFSPNGVNGGIRVPR
CHHHEEHEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]