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The map label for this gene is rbsR [H]

Identifier: 170023874

GI number: 170023874

Start: 1810082

End: 1811122

Strand: Reverse

Name: rbsR [H]

Synonym: YPK_1633

Alternate gene names: 170023874

Gene position: 1811122-1810082 (Counterclockwise)

Preceding gene: 170023882

Following gene: 170023873

Centisome position: 38.62

GC content: 46.78

Gene sequence:

>1041_bases
ATGACCACTGGTAAAAAAAGAGAAACGCTTAAAACCATCGCTGAAACGCTTAACGTAACGCATACAACGGTCTCGAATGT
GTTTAATCGGCCGGAAAAAGTATCGCCTGAATTGCGAGAGAAAATTTTAGCCTATGCCGAATCTATAAATTATCACGGTC
CTGCAGGTGCTGGCCGCTTTCTGCGGACCGGAAAATGTGGAACGCTTGGGGTCATCTTTAATGACAACCTCAGTTATGTT
TTCTCTGATCGCCATGATATTGCGTTGATGCGCGGTATTGCCGAAGAGTGCGAAAAGAATGGTATTAACATTGCACTGAT
GCCATTAAAAACGAATAACGCGCTAAAAAAACGGATGATGGGTGCACTGGTCGATGGTTATATTTTAAATGCGACCTATA
ACAATGACGAAGTGGTCCAGGCGGCGTTGACCAGTGGCTTGCCGGTCATTACCACCGATATCAAACTCCAGAATTTCACC
TGTGTTTCGATAGATGACGGGGCTGCTATGCAGGCTATTTGCCACCACTTGTTGGCAGCCGGGCATAAGAAATTCGGTAT
TGTCTCTTTCCCTGTGAAAAGGCTCCCCGGCGAGCTAACATCACTGGCTGAATTCTCCACTGACTATGACAATGGTGTGG
CTTTCGGGCGAATTAGCGCCTGTATAACCGCGCTGTCTGACGCTGGAATTGATTTGCACACCAGTTATGTCGCGGAACAA
CCGCACAGTGAAACCGGGGGCGAAAAAGCGGCCAAAGCGCTGCTGGCAAAGGAACCGGGTATTTCGGCTATTATTTGTTT
ATCTGACCGTTTTGCATTCGGCGTTTATCAATTTTGTCAGGACCACAATATTCCCGTGCCAGGCCAAATTGCCATTACCG
GGTTTGACGATATTGATATTCAGGATCCGCCGGTTGGTTTAACGACCATCCGCCAACCTACCGTTTTAAAAGGCCGTGAA
GCCGCAAGGGCCCTTATTTCAGGCCAATTAGACAATGATATATCTTTAGATTTTGAACTTGTCGTCCGTGATTCAGCATA
A

Upstream 100 bases:

>100_bases
TAACATGCTATTCCTGAACGGTGAGGTTTGATCATTTCACAAGACGGAGGGGGGTATAATACAGGCAGTTTGTTTAGTTC
TTCTTCCCGGAGCTTTTAAC

Downstream 100 bases:

>100_bases
TCAGATTGGAAAGGAAATGGAAAAATTAACCTGTTTTAAAGCTTACGATATTCGGGGAAAACTGGGCTCGGAGTTAAACG
AAGAGATAGCCTATCGAATC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRFLRTGKCGTLGVIFNDNLSYV
FSDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMMGALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFT
CVSIDDGAAMQAICHHLLAAGHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQ
PHSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDIQDPPVGLTTIRQPTVLKGRE
AARALISGQLDNDISLDFELVVRDSA

Sequences:

>Translated_346_residues
MTTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRFLRTGKCGTLGVIFNDNLSYV
FSDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMMGALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFT
CVSIDDGAAMQAICHHLLAAGHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQ
PHSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDIQDPPVGLTTIRQPTVLKGRE
AARALISGQLDNDISLDFELVVRDSA
>Mature_345_residues
TTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRFLRTGKCGTLGVIFNDNLSYVF
SDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMMGALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFTC
VSIDDGAAMQAICHHLLAAGHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQP
HSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDIQDPPVGLTTIRQPTVLKGREA
ARALISGQLDNDISLDFELVVRDSA

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=359, Percent_Identity=26.1838440111421, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=25.4545454545455, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787948, Length=317, Percent_Identity=22.397476340694, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789202, Length=318, Percent_Identity=25.7861635220126, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788474, Length=339, Percent_Identity=23.3038348082596, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787906, Length=283, Percent_Identity=25.4416961130742, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787580, Length=296, Percent_Identity=19.5945945945946, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37353; Mature: 37222

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRF
CCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
LRTGKCGTLGVIFNDNLSYVFSDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMM
EECCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHH
GALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFTCVSIDDGAAMQAICHHLLAA
HHHHCCEEEEEECCCHHHHHHHHHCCCCEEEEEEEEECEEEEEECCCHHHHHHHHHHHHC
GHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQ
CCCCCCEEECCHHHCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCEEEHHHHHCC
PHSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDI
CCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
QDPPVGLTTIRQPTVLKGREAARALISGQLDNDISLDFELVVRDSA
CCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCC
>Mature Secondary Structure 
TTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRF
CCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
LRTGKCGTLGVIFNDNLSYVFSDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMM
EECCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHH
GALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFTCVSIDDGAAMQAICHHLLAA
HHHHCCEEEEEECCCHHHHHHHHHCCCCEEEEEEEEECEEEEEECCCHHHHHHHHHHHHC
GHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQ
CCCCCCEEECCHHHCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCEEEHHHHHCC
PHSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDI
CCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
QDPPVGLTTIRQPTVLKGREAARALISGQLDNDISLDFELVVRDSA
CCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]