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The map label for this gene is ttuB [H]

Identifier: 170023821

GI number: 170023821

Start: 1748874

End: 1750190

Strand: Direct

Name: ttuB [H]

Synonym: YPK_1580

Alternate gene names: 170023821

Gene position: 1748874-1750190 (Clockwise)

Preceding gene: 170023820

Following gene: 170023822

Centisome position: 37.29

GC content: 50.04

Gene sequence:

>1317_bases
ATGGACAGTAAGATCCCTAATGCCCGTTGGTTCCGCGTTATTGTGCCAATAATGATTGCTTGTATTATTTCTTTTATGGA
TCGGGTCAATATTAGTTTTGCTCTACCGGGCGGTATGGAAAGTGATTTGGCGATTACCAGCCAAATGGCCGGTTTAGCCG
GCGGTATTTTCTTTATCGGTTATTTATTTCTACAAGTACCCGGTGGCCGTATTGCAGTACATGGCAGCGGCAGAAAATTC
ATTGCTTATTCTTTAGCGGTCTGGGCCATCGTCTCTATCCTGACCGGTTTTGTTACCCATCATTATCAATTGCTGTTTCT
GCGTTTTGTCTTGGGGGTTTCCGAAGGGGGTATGTTGCCCGTGGTATTGACCATGGTCAGCAACTGGTTCCCAGAGCGCG
AAATTGGCCGCGCTAATGCTTTCGTCATGATGTTTGCACCGATTGGCGGCATGTTCACCGCACCGTTGTCGGGTTTTATC
ATCAATACGCTCGACTGGCGTTGGTTATTCTTCCTTGAAGGCGGGTTGTCAGCACTGGTGTTGGTGATGTGGTGGTTTGT
GATCAGTGACCGCCCAGAGGAGGCCAAATGGCTATCAGCGCGAGAGCGTGATTATCTGGTCACTGAACTGTCGCGGGAAA
GAGCGGAACGAATGTTCAATAAGCCGGTGACCAATGCGCCGTTAAAAGCGGTATTTCTCAATAAAGGTTTGATGAAGCTG
GTGGCGCTGAACTTCTTCTACCAGACCGGGGATTATGGTTACACATTGTGGTTGCCCACTATCTTAAAAAACCTGACCGG
CGGCAATATGGCATCCGTCGGTATTCTGGCGGTGCTGCCATTTGTGGCTACCACCGCCGGTATTTATGTTATTTCCGCAC
TGGCGGATAAAACCGGTAAGCGCCGTCTGCTGATTATGATTTCCCTGTTCTGCTTTGCTGCGGCGTTGGTGGCATCGGTT
ATTTTCCGTCACAACGTTCTTGTGTCATATCTGGCATTGGTGGTCTGTGGCTTCTTCCTGAAAGCGGCAACCAGCCCATT
CTGGTCAATTCCTGGCCGTATTGCGGTGCCAGAAGTAGCTGGTGGTGCGCGGGGGGTGATTAACGGTTTAGGCAATCTGG
GGGGCTTCTGTGGCCCCTATCTGGTGGGGGTGATGATCTTCTTCTATGGCCAGAGCGCGGCGGTCTGCATGTTGGCGGGA
TCATTGATTATTGCTGGGCTGATTACCTTAACGTTGCCGAAAGAGTGTGATGTCGAGGTGAAATCTACAGGGAAAGATAT
CGCTGACAACGGTTTGACTAAAGCGAAACGTGCGTAA

Upstream 100 bases:

>100_bases
TTTTAAGGTCAACGACCAATAAATAATTTGGGCAATTGAGTATAGCCAACGTATATGCAGCTTGAAGTATGACGGATATA
TTATCATGAGGCGTATTTAT

Downstream 100 bases:

>100_bases
GCCGATGCCATTTATCACCGGAGAATCTGATGAATTTACAGCAACAACTCGCCTACTGTCAGCAGCACCAACAACGCTTG
CAACTGAGGCATTTCGATAA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MDSKIPNARWFRVIVPIMIACIISFMDRVNISFALPGGMESDLAITSQMAGLAGGIFFIGYLFLQVPGGRIAVHGSGRKF
IAYSLAVWAIVSILTGFVTHHYQLLFLRFVLGVSEGGMLPVVLTMVSNWFPEREIGRANAFVMMFAPIGGMFTAPLSGFI
INTLDWRWLFFLEGGLSALVLVMWWFVISDRPEEAKWLSARERDYLVTELSRERAERMFNKPVTNAPLKAVFLNKGLMKL
VALNFFYQTGDYGYTLWLPTILKNLTGGNMASVGILAVLPFVATTAGIYVISALADKTGKRRLLIMISLFCFAAALVASV
IFRHNVLVSYLALVVCGFFLKAATSPFWSIPGRIAVPEVAGGARGVINGLGNLGGFCGPYLVGVMIFFYGQSAAVCMLAG
SLIIAGLITLTLPKECDVEVKSTGKDIADNGLTKAKRA

Sequences:

>Translated_438_residues
MDSKIPNARWFRVIVPIMIACIISFMDRVNISFALPGGMESDLAITSQMAGLAGGIFFIGYLFLQVPGGRIAVHGSGRKF
IAYSLAVWAIVSILTGFVTHHYQLLFLRFVLGVSEGGMLPVVLTMVSNWFPEREIGRANAFVMMFAPIGGMFTAPLSGFI
INTLDWRWLFFLEGGLSALVLVMWWFVISDRPEEAKWLSARERDYLVTELSRERAERMFNKPVTNAPLKAVFLNKGLMKL
VALNFFYQTGDYGYTLWLPTILKNLTGGNMASVGILAVLPFVATTAGIYVISALADKTGKRRLLIMISLFCFAAALVASV
IFRHNVLVSYLALVVCGFFLKAATSPFWSIPGRIAVPEVAGGARGVINGLGNLGGFCGPYLVGVMIFFYGQSAAVCMLAG
SLIIAGLITLTLPKECDVEVKSTGKDIADNGLTKAKRA
>Mature_438_residues
MDSKIPNARWFRVIVPIMIACIISFMDRVNISFALPGGMESDLAITSQMAGLAGGIFFIGYLFLQVPGGRIAVHGSGRKF
IAYSLAVWAIVSILTGFVTHHYQLLFLRFVLGVSEGGMLPVVLTMVSNWFPEREIGRANAFVMMFAPIGGMFTAPLSGFI
INTLDWRWLFFLEGGLSALVLVMWWFVISDRPEEAKWLSARERDYLVTELSRERAERMFNKPVTNAPLKAVFLNKGLMKL
VALNFFYQTGDYGYTLWLPTILKNLTGGNMASVGILAVLPFVATTAGIYVISALADKTGKRRLLIMISLFCFAAALVASV
IFRHNVLVSYLALVVCGFFLKAATSPFWSIPGRIAVPEVAGGARGVINGLGNLGGFCGPYLVGVMIFFYGQSAAVCMLAG
SLIIAGLITLTLPKECDVEVKSTGKDIADNGLTKAKRA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=388, Percent_Identity=23.4536082474227, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI9945322, Length=385, Percent_Identity=24.1558441558442, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI9966811, Length=381, Percent_Identity=22.5721784776903, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI21322234, Length=409, Percent_Identity=24.6943765281174, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI148743791, Length=240, Percent_Identity=24.1666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4885441, Length=334, Percent_Identity=23.3532934131737, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI5031955, Length=256, Percent_Identity=24.21875, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI148728191, Length=157, Percent_Identity=26.7515923566879, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082071, Length=408, Percent_Identity=26.9607843137255, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87082320, Length=423, Percent_Identity=26.241134751773, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789515, Length=436, Percent_Identity=23.394495412844, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789152, Length=403, Percent_Identity=21.5880893300248, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367379, Length=303, Percent_Identity=23.7623762376238, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI2367193, Length=278, Percent_Identity=23.3812949640288, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788068, Length=377, Percent_Identity=22.0159151193634, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788074, Length=389, Percent_Identity=22.107969151671, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17552542, Length=417, Percent_Identity=23.9808153477218, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115533554, Length=414, Percent_Identity=24.1545893719807, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=414, Percent_Identity=24.1545893719807, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997452, Length=339, Percent_Identity=22.7138643067847, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=357, Percent_Identity=21.5686274509804, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=256, Percent_Identity=25.390625, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=256, Percent_Identity=25.390625, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=256, Percent_Identity=25.390625, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540458, Length=180, Percent_Identity=23.3333333333333, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193205400, Length=229, Percent_Identity=20.9606986899563, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20130167, Length=403, Percent_Identity=26.5508684863524, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24583789, Length=356, Percent_Identity=23.5955056179775, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24641682, Length=406, Percent_Identity=26.6009852216749, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24584153, Length=376, Percent_Identity=23.936170212766, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20130135, Length=402, Percent_Identity=24.3781094527363, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24655271, Length=402, Percent_Identity=24.3781094527363, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573708, Length=246, Percent_Identity=25.2032520325203, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573707, Length=246, Percent_Identity=25.2032520325203, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922400, Length=366, Percent_Identity=24.0437158469945, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24654215, Length=366, Percent_Identity=24.0437158469945, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648416, Length=259, Percent_Identity=24.3243243243243, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356189, Length=259, Percent_Identity=24.3243243243243, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24580790, Length=227, Percent_Identity=23.7885462555066, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24639764, Length=425, Percent_Identity=24.4705882352941, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI221474708, Length=402, Percent_Identity=22.1393034825871, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573299, Length=387, Percent_Identity=23.2558139534884, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45550460, Length=299, Percent_Identity=23.0769230769231, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24653727, Length=431, Percent_Identity=22.969837587007, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655255, Length=255, Percent_Identity=23.5294117647059, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658658, Length=348, Percent_Identity=22.9885057471264, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550364, Length=344, Percent_Identity=22.093023255814, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20129235, Length=402, Percent_Identity=23.134328358209, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24658696, Length=317, Percent_Identity=25.8675078864353, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47722; Mature: 47722

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKIPNARWFRVIVPIMIACIISFMDRVNISFALPGGMESDLAITSQMAGLAGGIFFIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
YLFLQVPGGRIAVHGSGRKFIAYSLAVWAIVSILTGFVTHHYQLLFLRFVLGVSEGGMLP
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VVLTMVSNWFPEREIGRANAFVMMFAPIGGMFTAPLSGFIINTLDWRWLFFLEGGLSALV
HHHHHHHCCCCCHHCCCCCEEEEEEECCCCHHHHCCHHHHHHCCCCEEEEEECCCHHHHH
LVMWWFVISDRPEEAKWLSARERDYLVTELSRERAERMFNKPVTNAPLKAVFLNKGLMKL
HHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VALNFFYQTGDYGYTLWLPTILKNLTGGNMASVGILAVLPFVATTAGIYVISALADKTGK
HHHHHHHCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RRLLIMISLFCFAAALVASVIFRHNVLVSYLALVVCGFFLKAATSPFWSIPGRIAVPEVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCC
GGARGVINGLGNLGGFCGPYLVGVMIFFYGQSAAVCMLAGSLIIAGLITLTLPKECDVEV
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCH
KSTGKDIADNGLTKAKRA
HCCCCHHHHCCCHHHCCC
>Mature Secondary Structure
MDSKIPNARWFRVIVPIMIACIISFMDRVNISFALPGGMESDLAITSQMAGLAGGIFFIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
YLFLQVPGGRIAVHGSGRKFIAYSLAVWAIVSILTGFVTHHYQLLFLRFVLGVSEGGMLP
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VVLTMVSNWFPEREIGRANAFVMMFAPIGGMFTAPLSGFIINTLDWRWLFFLEGGLSALV
HHHHHHHCCCCCHHCCCCCEEEEEEECCCCHHHHCCHHHHHHCCCCEEEEEECCCHHHHH
LVMWWFVISDRPEEAKWLSARERDYLVTELSRERAERMFNKPVTNAPLKAVFLNKGLMKL
HHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VALNFFYQTGDYGYTLWLPTILKNLTGGNMASVGILAVLPFVATTAGIYVISALADKTGK
HHHHHHHCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RRLLIMISLFCFAAALVASVIFRHNVLVSYLALVVCGFFLKAATSPFWSIPGRIAVPEVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCC
GGARGVINGLGNLGGFCGPYLVGVMIFFYGQSAAVCMLAGSLIIAGLITLTLPKECDVEV
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCH
KSTGKDIADNGLTKAKRA
HCCCCHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]