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The map label for this gene is hcp1 [H]

Identifier: 170023722

GI number: 170023722

Start: 1639755

End: 1640324

Strand: Direct

Name: hcp1 [H]

Synonym: YPK_1481

Alternate gene names: 170023722

Gene position: 1639755-1640324 (Clockwise)

Preceding gene: 170023721

Following gene: 170023723

Centisome position: 34.97

GC content: 41.4

Gene sequence:

>570_bases
ATGTGCCTCCGTATTTATATGGGGTCTTCCTACACTCGATGTTTGGCATTGAGTGACATTTATAAAAGTGCTAGAGAGGA
TATTATGGCGCAAGATATGTTTATCAAAATTGATGGTATTGAAGGTGAGTCTTTGGATGCCAATCACAAAAACGAAATCC
AGGTATTAGCTTGGAACTGGGATGTTGCTCAACACTCGAATATGCACAGCGGTTCAGGTGGCGGTTCAGGTAAAGCCTCT
GTTTCAGATTTTTGCTTCGCACATTATATCGATAAAGCTAGCCCGAACTTATTGAGCTATTGCTTGCTGGGTAAGCACAT
TAAAAATGTTCAGTTCGTACTGCGTAAAGCCGGTGGCGATCCGCTGGAATATCTGACAATTAAATTTACCGATGTCATCA
TTACTCGTGTTGATATGGCGGGTTCTTTGGAAGATGAAACGCGTCCACGTGAAGAAATTCGTTTCTCATTCACTAAGATG
ACTCAGGACTATGTTATGCAGAATGCTGAAGGCCATAAATCTGGCGTTATTTCTGCTAACTACGATGTTAAAGCTAACAT
GCACAGCTAA

Upstream 100 bases:

>100_bases
TCAGTATTCAATATTGAATGATGTAGTAATGGTTGTTCGTAAAGTATTTCAATAGTCAACTAAAAACTATTTTTATACTT
ATTTGTATCAAAGGAAAGGG

Downstream 100 bases:

>100_bases
TTACGTTGTTCATGTCGCTATCAAACTTGCCACCCTTGGGGTGGCAGGTTTTCTTAATAAGTGGTTTGAGTGACATATAC
GACAGGTACATCGTCCTAAC

Product: Hcp1 family type VI secretion system effector

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MCLRIYMGSSYTRCLALSDIYKSAREDIMAQDMFIKIDGIEGESLDANHKNEIQVLAWNWDVAQHSNMHSGSGGGSGKAS
VSDFCFAHYIDKASPNLLSYCLLGKHIKNVQFVLRKAGGDPLEYLTIKFTDVIITRVDMAGSLEDETRPREEIRFSFTKM
TQDYVMQNAEGHKSGVISANYDVKANMHS

Sequences:

>Translated_189_residues
MCLRIYMGSSYTRCLALSDIYKSAREDIMAQDMFIKIDGIEGESLDANHKNEIQVLAWNWDVAQHSNMHSGSGGGSGKAS
VSDFCFAHYIDKASPNLLSYCLLGKHIKNVQFVLRKAGGDPLEYLTIKFTDVIITRVDMAGSLEDETRPREEIRFSFTKM
TQDYVMQNAEGHKSGVISANYDVKANMHS
>Mature_189_residues
MCLRIYMGSSYTRCLALSDIYKSAREDIMAQDMFIKIDGIEGESLDANHKNEIQVLAWNWDVAQHSNMHSGSGGGSGKAS
VSDFCFAHYIDKASPNLLSYCLLGKHIKNVQFVLRKAGGDPLEYLTIKFTDVIITRVDMAGSLEDETRPREEIRFSFTKM
TQDYVMQNAEGHKSGVISANYDVKANMHS

Specific function: Required for assembly of the protein secretion apparatus HSI-I. Actively secreted during chronic infection of cystic fibrosis patients [H]

COG id: COG3157

COG function: function code S; Hemolysin-coregulated protein (uncharacterized)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hcp1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017728
- InterPro:   IPR008514 [H]

Pfam domain/function: PF05638 DUF796 [H]

EC number: NA

Molecular weight: Translated: 21172; Mature: 21172

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLRIYMGSSYTRCLALSDIYKSAREDIMAQDMFIKIDGIEGESLDANHKNEIQVLAWNW
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCEEEEEEEC
DVAQHSNMHSGSGGGSGKASVSDFCFAHYIDKASPNLLSYCLLGKHIKNVQFVLRKAGGD
CHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PLEYLTIKFTDVIITRVDMAGSLEDETRPREEIRFSFTKMTQDYVMQNAEGHKSGVISAN
CEEEEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
YDVKANMHS
CEEEECCCC
>Mature Secondary Structure
MCLRIYMGSSYTRCLALSDIYKSAREDIMAQDMFIKIDGIEGESLDANHKNEIQVLAWNW
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCEEEEEEEC
DVAQHSNMHSGSGGGSGKASVSDFCFAHYIDKASPNLLSYCLLGKHIKNVQFVLRKAGGD
CHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PLEYLTIKFTDVIITRVDMAGSLEDETRPREEIRFSFTKMTQDYVMQNAEGHKSGVISAN
CEEEEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
YDVKANMHS
CEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]