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The map label for this gene is fbpA [H]

Identifier: 170023704

GI number: 170023704

Start: 1614711

End: 1615730

Strand: Reverse

Name: fbpA [H]

Synonym: YPK_1463

Alternate gene names: 170023704

Gene position: 1615730-1614711 (Counterclockwise)

Preceding gene: 170023707

Following gene: 170023703

Centisome position: 34.45

GC content: 48.63

Gene sequence:

>1020_bases
ATGAAAATACCTATACCCTCTATTGGCCATGTTGCTTTACTGGCGTCTGCAATCCTGTTTGCGAGCTCTGCCAATGCTGC
CTCAGATGAAGATGGCATTATCATCTACAATGCGCAGCATGAAAGTTTTGCAAAATCTTGGGCTGAAGGTTTCACCAAAG
ATACGGGTATCAAAGTCACGCTACGTAATGGTAAAGACAGTGAATTGGGCAATCAATTGATTCAGGAGGGCAGTTCATCG
CCTGCCGATGTTTTCCTAACCGAGAACTCCCCGGCCATGGTGTTAGTTGATAATGCCAAATTGTTTGCTCCGCTGGATGC
CGCAACGCTAGCGCAAGTTGCTAAAGAATACCGGCCTGAAGATGGGCGCTGGACCGGCATTGCCGCTCGCAGCACGGTAT
TTGTTTATAATCCGGCAAAAATCAGCGAGTCAGAACTGCCTAAATCCTTAATGGACCTGGCGAAACCAGAGTGGAAAGGC
CGCTGGGCAGCTTCACCCTCCGGTGCTGACTTCCAGGCGATTGTCAGTGCGATGCTTGCGCTAAAAGGTGAACAAGCCAC
CTTAGAGTGGTTAAAAGCCATGAAAACCAATGCGACAGCATATAAAGGCAATAGCACCGTGATGAAAGCCGTGAACGCCG
GCCAAATTGATGGTGGCGTTATTTATCATTACTATCCCTTTGTTGATCAAGCTAAAACCGGTGAGAACAGCGGTAATATT
AAACTGCATTACTTCAAAAACAAGGATCCCGGTGCCTTCGTCAGTATCTCTGGCGCGGGGGTATTGGCTTCCAGCAAACA
TCCGCAGCAAGCCCAGAAATTCGTACAATGGGTCACCGGTAAAGCGGGGCAGGATTTCTTGCGCGAGAGCAATAGCGCCT
TTGAATATGCGGTTGGCGTGAATGCCGCTTCCAATCCTAAATTGGTGCCACTGAAAGATTTGGATCCGCCGAAAGTAGAG
GTGTCTAAACTGAACAGCAAAAAAGTGGTTGAGTTGATGACCGAAGCGGGTCTGCTGTAA

Upstream 100 bases:

>100_bases
TAATCATTTTTATTACCATAATTCGTTTCTTTCTATACAATCATTTTGCACTTGCCTGGCAACGTCGTTTTCTTCCCTGA
CCTTTTAAAAGGATCGTTAT

Downstream 100 bases:

>100_bases
TCCGTTTTACTCCGCCCCCTGCGGGCGTTTAACAAACCGAGTGTCTTTACCGATTATGTCCAATATAAGTACCGATGTTG
CACAGGCTGCACTGAGTAAG

Product: extracellular solute-binding protein

Products: ADP; phosphate; thiamine [Cytoplasm] [C]

Alternate protein names: Iron(III)-binding periplasmic protein [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKIPIPSIGHVALLASAILFASSANAASDEDGIIIYNAQHESFAKSWAEGFTKDTGIKVTLRNGKDSELGNQLIQEGSSS
PADVFLTENSPAMVLVDNAKLFAPLDAATLAQVAKEYRPEDGRWTGIAARSTVFVYNPAKISESELPKSLMDLAKPEWKG
RWAASPSGADFQAIVSAMLALKGEQATLEWLKAMKTNATAYKGNSTVMKAVNAGQIDGGVIYHYYPFVDQAKTGENSGNI
KLHYFKNKDPGAFVSISGAGVLASSKHPQQAQKFVQWVTGKAGQDFLRESNSAFEYAVGVNAASNPKLVPLKDLDPPKVE
VSKLNSKKVVELMTEAGLL

Sequences:

>Translated_339_residues
MKIPIPSIGHVALLASAILFASSANAASDEDGIIIYNAQHESFAKSWAEGFTKDTGIKVTLRNGKDSELGNQLIQEGSSS
PADVFLTENSPAMVLVDNAKLFAPLDAATLAQVAKEYRPEDGRWTGIAARSTVFVYNPAKISESELPKSLMDLAKPEWKG
RWAASPSGADFQAIVSAMLALKGEQATLEWLKAMKTNATAYKGNSTVMKAVNAGQIDGGVIYHYYPFVDQAKTGENSGNI
KLHYFKNKDPGAFVSISGAGVLASSKHPQQAQKFVQWVTGKAGQDFLRESNSAFEYAVGVNAASNPKLVPLKDLDPPKVE
VSKLNSKKVVELMTEAGLL
>Mature_339_residues
MKIPIPSIGHVALLASAILFASSANAASDEDGIIIYNAQHESFAKSWAEGFTKDTGIKVTLRNGKDSELGNQLIQEGSSS
PADVFLTENSPAMVLVDNAKLFAPLDAATLAQVAKEYRPEDGRWTGIAARSTVFVYNPAKISESELPKSLMDLAKPEWKG
RWAASPSGADFQAIVSAMLALKGEQATLEWLKAMKTNATAYKGNSTVMKAVNAGQIDGGVIYHYYPFVDQAKTGENSGNI
KLHYFKNKDPGAFVSISGAGVLASSKHPQQAQKFVQWVTGKAGQDFLRESNSAFEYAVGVNAASNPKLVPLKDLDPPKVE
VSKLNSKKVVELMTEAGLL

Specific function: Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. This protein specifically binds Fe(3+) and is involved in its transmembrane transport [H]

COG id: COG1840

COG function: function code P; ABC-type Fe3+ transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR006061 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 36338; Mature: 36338

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS01037 SBP_BACTERIAL_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPIPSIGHVALLASAILFASSANAASDEDGIIIYNAQHESFAKSWAEGFTKDTGIKVT
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCEEEE
LRNGKDSELGNQLIQEGSSSPADVFLTENSPAMVLVDNAKLFAPLDAATLAQVAKEYRPE
ECCCCCHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCEEEECCCHHHHHHHHHHHCCC
DGRWTGIAARSTVFVYNPAKISESELPKSLMDLAKPEWKGRWAASPSGADFQAIVSAMLA
CCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKGEQATLEWLKAMKTNATAYKGNSTVMKAVNAGQIDGGVIYHYYPFVDQAKTGENSGNI
HCCCHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCE
KLHYFKNKDPGAFVSISGAGVLASSKHPQQAQKFVQWVTGKAGQDFLRESNSAFEYAVGV
EEEEEECCCCCCEEEEECCEEEECCCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEC
NAASNPKLVPLKDLDPPKVEVSKLNSKKVVELMTEAGLL
CCCCCCCEEEECCCCCCCEEHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIPIPSIGHVALLASAILFASSANAASDEDGIIIYNAQHESFAKSWAEGFTKDTGIKVT
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCEEEE
LRNGKDSELGNQLIQEGSSSPADVFLTENSPAMVLVDNAKLFAPLDAATLAQVAKEYRPE
ECCCCCHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCEEEECCCHHHHHHHHHHHCCC
DGRWTGIAARSTVFVYNPAKISESELPKSLMDLAKPEWKGRWAASPSGADFQAIVSAMLA
CCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKGEQATLEWLKAMKTNATAYKGNSTVMKAVNAGQIDGGVIYHYYPFVDQAKTGENSGNI
HCCCHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCE
KLHYFKNKDPGAFVSISGAGVLASSKHPQQAQKFVQWVTGKAGQDFLRESNSAFEYAVGV
EEEEEECCCCCCEEEEECCEEEECCCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEC
NAASNPKLVPLKDLDPPKVEVSKLNSKKVVELMTEAGLL
CCCCCCCEEEECCCCCCCEEHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine [Periplasm]; H2O [C]

Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404942 [H]