Click here to switch to the map view.

The map label for this gene is ydeN [H]

Identifier: 170023620

GI number: 170023620

Start: 1517450

End: 1519123

Strand: Direct

Name: ydeN [H]

Synonym: YPK_1378

Alternate gene names: 170023620

Gene position: 1517450-1519123 (Clockwise)

Preceding gene: 170023619

Following gene: 170023621

Centisome position: 32.36

GC content: 42.05

Gene sequence:

>1674_bases
ATGATGAATTTAAAGGTTAACAGGAGCATTATTAGTGCTTCGATATCGGTCATCTTAGCTGCGGGCGTCATGGGTGGCCC
TGCATATGCTGATGATGTCAAACTCAAAGCAACAAACACCAATGTTGCTTTCGCTGATTTTACGCCAAAAGAATACAGCA
CGAAGAATAAGCCAAATATCATTGTCTTAACCATGGATGACTTAGGTTATGGGCAGCTCCCTTTTGATAAGACCTCCTTT
GACCCTAAGTCGATGGAAGATCGGGACGTTGTTGATACCTACAAAATAGGCATTGATAAAGCCATTGAAGCCGCCAAAAA
GTCCACGCCAACACTACTCTCGTTGATGGATGAAGGGGTTCGTCTGACGAATGGCTACGTTGCTCATGGCGTATCAGGGC
CTTCGCGGGCGGCCATTATGACGGGCCGGTCCCCTGCAAGGTTTGGTGTTTACTCCAATACCGATGCTCAGAATGGGATT
TCATTAGAAGAGACATTCCTGCCTGAGTTATTGCAAAACAATGGCTATTACACGGCGGCCATCGGAAAATGGCATCTTTC
AAAAATCAGTAATGTTCCTGTTCCTGAAGCGGAGCAAACGCGCGATTACCACGATAACTTTACAACTTACTCAGCCGATG
AATGGCAGCCTCAAAACCGAGGCTTCCAGTATTTTATGGGTTACCATGCCGCGGGAACGGCTTATTATAATTCCCCGTCT
CTTTTCCATAATAAAGAGCGGGTGAAAGCCAAAGGTTATATCAGTGATCAACTTACCGATGAGGCTATCGGTGTTGCCAA
TAGAGCTAAATCCTTAGATGAGCCATTCATGATGTATTTGGCTTACAGTGCTCCCCATTTACCTAATGATAATCCAGCGC
CGGATGAATATCAGAAACACTTTAATACAGGTAGCCAAACTGCTGATAACTTCTATGCCTCTGTCTATTCTGTTGACCAG
GGCGTAAAACGGCTTCTTGAGCAGCTTAAAAAGAATGGTCAATATGACAATACGATAATTATGTTTACCTCTGATAACGG
TGCCGTTATCGATGGGCCATTACCGTTGAACGGTAATCAGAAAGGGTATAAAAGCCAAACATTTCCTGGCGGAACCCATA
CTCCAATGTTTATTTGGTGGAAGGGGAAATTGCAAACAGGAAATTATGACAAGTTGATCTCTGCAATGGATTTCATGCCT
ACAGCGCTTGAAGCCGCTGAGATTGATGCTCCAAATAATTTAGATGGTGTCTCACTGCTTCCTTATTTGACGGGGAAAAG
CAAAGCTGAACCGCATAAATATCTTACCTGGGTGACATCCTATACCCACTGGTTCGATGAAGAGAATATTCCATTCTGGG
ATGGTTACCATAAATTTGTGCGTAATGAATCCAATGAATATCCTAAAAACCCAAATACCGAAGATCTTAGTCAATTCTCT
TATACCATCCGCAGTAATGACTACTCTTTAACCTATACCTATGAAGGTAATAAGTTAAATCTGTATAAACTGAGTGATTT
AAATCAAAAACAAGACCTTGCAAGTACCCATCCTGATGTTGTTAAGGTAATGCAAGCCGAGATGAGGAACTTCATTAATC
AGAGTCAATCTCCTGTTAGTGAAGTTAATCAGGATAAATTTAATAAAATTAAGCAATCGCTTGGTATGAATTAA

Upstream 100 bases:

>100_bases
TTGCGATATTCATATCTTTTTAATCCACCAGACCGATCACATTAATTCTTATTTTTAGACGTAAAATATCAATTGGACGA
TAACCAGTAGAGAACTAAAA

Downstream 100 bases:

>100_bases
GCCCCAAAGGCGGCAAGTATTTTTCTTGCCGTCTGTCTATCTCCATGAGGAAAACTATGCATATCACGGCTAAACCAACC
AGCTACCAGTGTAATTTAAA

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MMNLKVNRSIISASISVILAAGVMGGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNIIVLTMDDLGYGQLPFDKTSF
DPKSMEDRDVVDTYKIGIDKAIEAAKKSTPTLLSLMDEGVRLTNGYVAHGVSGPSRAAIMTGRSPARFGVYSNTDAQNGI
SLEETFLPELLQNNGYYTAAIGKWHLSKISNVPVPEAEQTRDYHDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPS
LFHNKERVKAKGYISDQLTDEAIGVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKHFNTGSQTADNFYASVYSVDQ
GVKRLLEQLKKNGQYDNTIIMFTSDNGAVIDGPLPLNGNQKGYKSQTFPGGTHTPMFIWWKGKLQTGNYDKLISAMDFMP
TALEAAEIDAPNNLDGVSLLPYLTGKSKAEPHKYLTWVTSYTHWFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFS
YTIRSNDYSLTYTYEGNKLNLYKLSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVSEVNQDKFNKIKQSLGMN

Sequences:

>Translated_557_residues
MMNLKVNRSIISASISVILAAGVMGGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNIIVLTMDDLGYGQLPFDKTSF
DPKSMEDRDVVDTYKIGIDKAIEAAKKSTPTLLSLMDEGVRLTNGYVAHGVSGPSRAAIMTGRSPARFGVYSNTDAQNGI
SLEETFLPELLQNNGYYTAAIGKWHLSKISNVPVPEAEQTRDYHDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPS
LFHNKERVKAKGYISDQLTDEAIGVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKHFNTGSQTADNFYASVYSVDQ
GVKRLLEQLKKNGQYDNTIIMFTSDNGAVIDGPLPLNGNQKGYKSQTFPGGTHTPMFIWWKGKLQTGNYDKLISAMDFMP
TALEAAEIDAPNNLDGVSLLPYLTGKSKAEPHKYLTWVTSYTHWFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFS
YTIRSNDYSLTYTYEGNKLNLYKLSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVSEVNQDKFNKIKQSLGMN
>Mature_557_residues
MMNLKVNRSIISASISVILAAGVMGGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNIIVLTMDDLGYGQLPFDKTSF
DPKSMEDRDVVDTYKIGIDKAIEAAKKSTPTLLSLMDEGVRLTNGYVAHGVSGPSRAAIMTGRSPARFGVYSNTDAQNGI
SLEETFLPELLQNNGYYTAAIGKWHLSKISNVPVPEAEQTRDYHDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPS
LFHNKERVKAKGYISDQLTDEAIGVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKHFNTGSQTADNFYASVYSVDQ
GVKRLLEQLKKNGQYDNTIIMFTSDNGAVIDGPLPLNGNQKGYKSQTFPGGTHTPMFIWWKGKLQTGNYDKLISAMDFMP
TALEAAEIDAPNNLDGVSLLPYLTGKSKAEPHKYLTWVTSYTHWFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFS
YTIRSNDYSLTYTYEGNKLNLYKLSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVSEVNQDKFNKIKQSLGMN

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=387, Percent_Identity=28.9405684754522, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI146229331, Length=419, Percent_Identity=26.2529832935561, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI146229329, Length=419, Percent_Identity=26.2529832935561, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI6005990, Length=419, Percent_Identity=26.2529832935561, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI146229324, Length=419, Percent_Identity=26.2529832935561, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI45430057, Length=440, Percent_Identity=25.9090909090909, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI59797060, Length=483, Percent_Identity=26.0869565217391, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI109389362, Length=341, Percent_Identity=26.9794721407625, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38569407, Length=376, Percent_Identity=25.531914893617, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38569405, Length=376, Percent_Identity=25.531914893617, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4504061, Length=377, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI58743319, Length=184, Percent_Identity=32.6086956521739, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI53831991, Length=185, Percent_Identity=30.2702702702703, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI87081924, Length=556, Percent_Identity=80.0359712230216, Blast_Score=935, Evalue=0.0,
Organism=Escherichia coli, GI1790233, Length=397, Percent_Identity=26.9521410579345, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115533416, Length=535, Percent_Identity=24.1121495327103, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI115533418, Length=490, Percent_Identity=25.1020408163265, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24666109, Length=410, Percent_Identity=29.0243902439024, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI281366397, Length=395, Percent_Identity=29.3670886075949, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI281366395, Length=395, Percent_Identity=29.3670886075949, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24666163, Length=395, Percent_Identity=29.3670886075949, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24666175, Length=412, Percent_Identity=26.2135922330097, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363223, Length=374, Percent_Identity=25.9358288770053, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647401, Length=363, Percent_Identity=23.4159779614325, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24653364, Length=352, Percent_Identity=24.7159090909091, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922168, Length=352, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 62486; Mature: 62486

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNLKVNRSIISASISVILAAGVMGGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNI
CCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCCHHCCCCCCCCE
IVLTMDDLGYGQLPFDKTSFDPKSMEDRDVVDTYKIGIDKAIEAAKKSTPTLLSLMDEGV
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHCCCCHHHHHHHCCC
RLTNGYVAHGVSGPSRAAIMTGRSPARFGVYSNTDAQNGISLEETFLPELLQNNGYYTAA
EEECCEEEECCCCCCCEEEEECCCCCEECEECCCCCCCCCCHHHHHHHHHHHCCCEEEEE
IGKWHLSKISNVPVPEAEQTRDYHDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPS
ECCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCH
LFHNKERVKAKGYISDQLTDEAIGVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKH
HHCCHHHHEECCCCCHHHHHHHHHHHHHHHCCCCHHEEHEECCCCCCCCCCCCCHHHHHH
FNTGSQTADNFYASVYSVDQGVKRLLEQLKKNGQYDNTIIMFTSDNGAVIDGPLPLNGNQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCCC
KGYKSQTFPGGTHTPMFIWWKGKLQTGNYDKLISAMDFMPTALEAAEIDAPNNLDGVSLL
CCCCCCCCCCCCCCCEEEEEECEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
PYLTGKSKAEPHKYLTWVTSYTHWFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFS
EEECCCCCCCCHHHEEHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHE
YTIRSNDYSLTYTYEGNKLNLYKLSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVS
EEEECCCEEEEEEEECCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHH
EVNQDKFNKIKQSLGMN
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMNLKVNRSIISASISVILAAGVMGGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNI
CCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCCHHCCCCCCCCE
IVLTMDDLGYGQLPFDKTSFDPKSMEDRDVVDTYKIGIDKAIEAAKKSTPTLLSLMDEGV
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHCCCCHHHHHHHCCC
RLTNGYVAHGVSGPSRAAIMTGRSPARFGVYSNTDAQNGISLEETFLPELLQNNGYYTAA
EEECCEEEECCCCCCCEEEEECCCCCEECEECCCCCCCCCCHHHHHHHHHHHCCCEEEEE
IGKWHLSKISNVPVPEAEQTRDYHDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPS
ECCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCH
LFHNKERVKAKGYISDQLTDEAIGVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKH
HHCCHHHHEECCCCCHHHHHHHHHHHHHHHCCCCHHEEHEECCCCCCCCCCCCCHHHHHH
FNTGSQTADNFYASVYSVDQGVKRLLEQLKKNGQYDNTIIMFTSDNGAVIDGPLPLNGNQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCCC
KGYKSQTFPGGTHTPMFIWWKGKLQTGNYDKLISAMDFMPTALEAAEIDAPNNLDGVSLL
CCCCCCCCCCCCCCCEEEEEECEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
PYLTGKSKAEPHKYLTWVTSYTHWFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFS
EEECCCCCCCCHHHEEHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHE
YTIRSNDYSLTYTYEGNKLNLYKLSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVS
EEEECCCEEEEEEEECCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHH
EVNQDKFNKIKQSLGMN
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]