Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 170022723

GI number: 170022723

Start: 516724

End: 518169

Strand: Direct

Name: tldD [H]

Synonym: YPK_0472

Alternate gene names: 170022723

Gene position: 516724-518169 (Clockwise)

Preceding gene: 170022722

Following gene: 170022734

Centisome position: 11.02

GC content: 53.6

Gene sequence:

>1446_bases
ATGAGCCTCTCATTTGTCAGTGAGCAGTTACTCACTGCTAACAAGTTGAACCATGAGGACTTGTTCTCAGTGTTGGGGCA
GCTAACTGAACGCCGCCTCGATTATGCTGACCTGTATTTCCAGTCCAGCTATCACGAGGCCTGGGTGTTGGAAGACAGCA
TCATCAAAGACGGCTCCTACAATATTGATCAGGGTGTGGGCGTACGTGCGGTAAGTGGTGAAAAAACCGGTTTTGCCTAC
GCTGACCAAATCACGTTGAATGCGTTGCAGCAAAGTGCCCATGCGGCCCGCAGTATTGTTCGTGATACTGGCAACGGCAA
AGTCCATACCTTGGGTGAGATTGCCTATCAAGCCTTGTACCCGTTGCTTGATCCACTACAAAGCCTATCGCGGGAAGATA
AAATTGCCTTGTTACATCGGGTCGATAAAGTCGCTCGCGCCGCCGATAAACGGGTGCAGGAAGTTAGCGCCAGTCTGACC
GGCGTGTATGAACAGATTCTGGTGGCTGCGACTGACGGCACCTTGGCTGCCGATGTGCGTCCGTTGGTCCGTCTTTCGGT
CAGTGTACTGGTGGAAGACAACGGTAAACGTGAACGCGGTGCTTGCGGTGGCGGTGGCCGTTTCGGTTATGACTATTTCC
TTGAAACCGTTGATGGCGAAGTGCGGGCAGATAATTTTGCTAATGAAGCGGTCAGAATGGCGCTGGTTAATCTTTCGGCT
ATTGCCGCTCCAGCGGGTGCGATGCCGGTAGTGTTAGGCGCAGGCTGGCCGGGTGTGCTGTTACATGAAGCGGTTGGTCA
CGGACTGGAAGGTGATTTCAACCGTCGAGGCAGTTCGGTATTCAGTGGGCAAATGGGCAAATTGGTGGCTTCAGAACTCT
GTACGGTGGTGGACGATGGCACCATGCAAGGCCGCCGTGGCTCACTGGCTATCGACGATGAAGGGGTGCCGGGTCAATAT
AACGTGTTGATCGAAAATGGCATTCTGAAAGGGTATATGCAGGATAAACTGAACGCGCGTCTGATGGGGGTAGCCCCAAC
AGGTAATGGCCGCCGCGAATCCTATGCGCACCTGCCGATGCCACGCATGACCAACACCTATATGCTGGCAGGCCAATCGA
CACCGGAAGATATTATCGCCAGCGTGGAGTACGGCCTGTATGCGCCAAATTTTGGTGGCGGTCAGGTGGATATCACCTCT
GGCAAGTTTGTCTTCTCAACGTCGGAAGCGTACTTAATCGAAAAAGGCAAAATCACTCATGCGGTGAAAGGAGCCACCCT
GATTGGCTCTGGCATTGAAGCGATGCAGCAGATTTCTATGGTCGGCAACGATCTGGCGCTGGATAAAGGCGTTGGTGTTT
GTGGCAAAGAGGGCCAAAGCCTGCCGGTGGGTGTCGGCCAACCCACGTTGAAGTTGGATAATTTAACCGTGGGCGGCACG
GCGTAG

Upstream 100 bases:

>100_bases
AAATGCCGGTCATGCAGCACAATCGCTTTCAGGCGACGCTGGAGCCGACATTGAATAAACCATTATTGAATAAACCACCA
TCTAATTAAGAGTAAAAACT

Downstream 100 bases:

>100_bases
GGGCGCTCGAAAATACAATATGGGTAGTAGACTTTGTTGGCACTAAATTTGATATTAAATTTTGTGCCAACAAAGCATCG
GTATATTAGTTCAACCTATT

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLSFVSEQLLTANKLNHEDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAY
ADQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALYPLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLT
GVYEQILVAATDGTLAADVRPLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSA
IAAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDGTMQGRRGSLAIDDEGVPGQY
NVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITS
GKFVFSTSEAYLIEKGKITHAVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGT
A

Sequences:

>Translated_481_residues
MSLSFVSEQLLTANKLNHEDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAY
ADQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALYPLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLT
GVYEQILVAATDGTLAADVRPLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSA
IAAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDGTMQGRRGSLAIDDEGVPGQY
NVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITS
GKFVFSTSEAYLIEKGKITHAVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGT
A
>Mature_480_residues
SLSFVSEQLLTANKLNHEDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAYA
DQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALYPLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLTG
VYEQILVAATDGTLAADVRPLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSAI
AAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDGTMQGRRGSLAIDDEGVPGQYN
VLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITSG
KFVFSTSEAYLIEKGKITHAVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=84.1995841995842, Blast_Score=807, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=408, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51191; Mature: 51059

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSFVSEQLLTANKLNHEDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSY
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEEEEHHHCCCCCC
NIDQGVGVRAVSGEKTGFAYADQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALY
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
PLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLTGVYEQILVAATDGTLAADVR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
PLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSA
HHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
IAAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDG
HHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCC
TMQGRRGSLAIDDEGVPGQYNVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CCCCCCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITSGKFVFSTSEAYLIEKGKITH
CCCCCEEEEECCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCEEE
AVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGT
HCCCCCEEHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C
>Mature Secondary Structure 
SLSFVSEQLLTANKLNHEDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSY
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEEEEHHHCCCCCC
NIDQGVGVRAVSGEKTGFAYADQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALY
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
PLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLTGVYEQILVAATDGTLAADVR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
PLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSA
HHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
IAAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDG
HHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCC
TMQGRRGSLAIDDEGVPGQYNVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CCCCCCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITSGKFVFSTSEAYLIEKGKITH
CCCCCEEEEECCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCEEE
AVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGT
HCCCCCEEHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]