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The map label for this gene is nisX1 [H]

Identifier: 170016353

GI number: 170016353

Start: 35308

End: 35862

Strand: Direct

Name: nisX1 [H]

Synonym: LCK_p100046

Alternate gene names: 170016353

Gene position: 35308-35862 (Clockwise)

Preceding gene: 170016352

Following gene: 170016354

Centisome position: 91.2

GC content: 45.41

Gene sequence:

>555_bases
ATGAGCCTTAAATCTCGCATGGTCAGGAAGTCATATAAGAAGCCGACGACGACCACTGACACACCACAAAAGCCCAATCT
CATGAAGAATTTGGATGATTTGAGTGGCGTTCTAACGACTGACATCACGTACATCCAGCTGATGAATAGAAACTGGGTTT
ACCTGGCGACGGTCTATGACCCAGAAAAACGCCGTGTTGTCTCATATGGACTGAGTTCAGAGATGACCAAAGAATTCGCA
ACATCTGTTGTCGTGAAAGCTCTAAGAGCCAACGGTAAACCAAAGATGATTCACAGCGACATGGGAAGCCAGTACACTTC
AAGTCTGTTCGAAGGAACGTTGCAAAACGCTGGGATAGATCATTCTTACTCGCGTAAGGGGCATCCTTACGACAACGCAC
GTATCGAGAGCTTTCATTCGCTCATCAAGCGTGAGCTGATTTATCATGAAGAATACAGAACCATTGATGATGTCAGGGCA
TCTGTCGAATGGTATGTGAACTGGTACAACAACGAACGTATTAATTCACGCATTGAATGGCTTCAAGCCTCCTAG

Upstream 100 bases:

>100_bases
TACAACACCAATCGTTTGATCTATGGCTACCGCCGCATTTTTACGGTTCATTTTGAACACTGAAGTTGGTGATCGTTTGG
TTTGGGAGCTCATGAATGAG

Downstream 100 bases:

>100_bases
ACCAATGTTTGGTTGACTTAATCTCGGTTATCGGCACTAGCCGTTTATGAGCCGTCACTTGTGAATTTCACAAATTCGCC
TTGTGAAGGCTTATTTGTTG

Product: ORFC of IS3-like IS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSLKSRMVRKSYKKPTTTTDTPQKPNLMKNLDDLSGVLTTDITYIQLMNRNWVYLATVYDPEKRRVVSYGLSSEMTKEFA
TSVVVKALRANGKPKMIHSDMGSQYTSSLFEGTLQNAGIDHSYSRKGHPYDNARIESFHSLIKRELIYHEEYRTIDDVRA
SVEWYVNWYNNERINSRIEWLQAS

Sequences:

>Translated_184_residues
MSLKSRMVRKSYKKPTTTTDTPQKPNLMKNLDDLSGVLTTDITYIQLMNRNWVYLATVYDPEKRRVVSYGLSSEMTKEFA
TSVVVKALRANGKPKMIHSDMGSQYTSSLFEGTLQNAGIDHSYSRKGHPYDNARIESFHSLIKRELIYHEEYRTIDDVRA
SVEWYVNWYNNERINSRIEWLQAS
>Mature_183_residues
SLKSRMVRKSYKKPTTTTDTPQKPNLMKNLDDLSGVLTTDITYIQLMNRNWVYLATVYDPEKRRVVSYGLSSEMTKEFAT
SVVVKALRANGKPKMIHSDMGSQYTSSLFEGTLQNAGIDHSYSRKGHPYDNARIESFHSLIKRELIYHEEYRTIDDVRAS
VEWYVNWYNNERINSRIEWLQAS

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=135, Percent_Identity=34.0740740740741, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788405, Length=181, Percent_Identity=31.4917127071823, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787263, Length=181, Percent_Identity=31.4917127071823, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786753, Length=181, Percent_Identity=31.4917127071823, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786570, Length=181, Percent_Identity=31.4917127071823, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786490, Length=181, Percent_Identity=31.4917127071823, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789981, Length=146, Percent_Identity=32.1917808219178, Blast_Score=77, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 21457; Mature: 21325

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKSRMVRKSYKKPTTTTDTPQKPNLMKNLDDLSGVLTTDITYIQLMNRNWVYLATVYD
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEEEC
PEKRRVVSYGLSSEMTKEFATSVVVKALRANGKPKMIHSDMGSQYTSSLFEGTLQNAGID
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHCHHHHHHHHHHHHHHCCCC
HSYSRKGHPYDNARIESFHSLIKRELIYHEEYRTIDDVRASVEWYVNWYNNERINSRIEW
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
LQAS
HCCC
>Mature Secondary Structure 
SLKSRMVRKSYKKPTTTTDTPQKPNLMKNLDDLSGVLTTDITYIQLMNRNWVYLATVYD
CHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEEEC
PEKRRVVSYGLSSEMTKEFATSVVVKALRANGKPKMIHSDMGSQYTSSLFEGTLQNAGID
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHCHHHHHHHHHHHHHHCCCC
HSYSRKGHPYDNARIESFHSLIKRELIYHEEYRTIDDVRASVEWYVNWYNNERINSRIEW
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
LQAS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]