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The map label for this gene is mnaA [H]

Identifier: 169834375

GI number: 169834375

Start: 415157

End: 416245

Strand: Direct

Name: mnaA [H]

Synonym: SPH_0465

Alternate gene names: 169834375

Gene position: 415157-416245 (Clockwise)

Preceding gene: 169833780

Following gene: 169833959

Centisome position: 18.49

GC content: 36.91

Gene sequence:

>1089_bases
ATGAAAAAAATTATGTTAGTATTCGGTACACGTCCGGAAGCCATCAAAATGTGTCCATTAGTCAATGAGTTGAAAAAACA
CGAAGATATGGAAACAATTGTGTGTGTTACTGGACAACACAAAGAGATGGTTAGTCCTGTTTTAGATTTATTTGGTGTTG
TACCAGATTATGATTTAGAAATTATGAAGGCTAACCAAACCTTGTTCTCTATCACAACTAGTATCTTGGAAAAGATAAAA
CCAGTTTTAGAGAAGGAACAACCAGATATTGTCCTAGTTCACGGTGACACTACGACAACTTATGCAGCAGCCTTGGCAGC
ATTCTATTTGGGAATTAAAGTAGGACATGTTGAAGCTGGTTTGCGAACGTACAATTTACAAAGTCCATTTCCTGAAGAAT
TTAACAGGCAATCGACATCAATCATTGCAACTTACCATTTTGCTCCAACTGAGTTGGCTAAAGAAAATCTCTTAAAAGAA
GGTAGAGAGAATGTTTATGTGACTGGAAATACTGTCATTGATGCTCTTACAACTACTGTTCAAGAGGATTATACACACAC
TCATTTAGATTTAAACGCTAACAATCGTCTCATCTTATTGACTGCTCATAGACGCGAAAATCTCGGCGAACCGATGAGAC
ATATGTTTAGAGCAGTTAAACGAGTATTGAATGAATACGAAGATGTTAAAGTCATTTATCCAATTCATAAGAATCCTTTG
GTACGTGAAACAGCTGCAGAGATCTTTGGAGATACAGAACGGATTCAAATTATTGAACCTTTGGATGTTCTTGATTTCCA
CAACTTCATGAACCAAAGTTATATGATTTTAACAGATTCTGGCGGAGTTCAGGAAGAAGCACCTTCTTTAGGAAAACCTG
TATTGGTTATGCGCGATACTACTGAAAGACCTGAAGGAGTAGCGGCAGGAACCTTGAAATTAGTAGGAACTGACGAAGAA
ACAATTTATCAAAACTTCAAACTACTTCTAGATGATTCTGGAGAATACAAAAAAATGAGTCAGGCTAGCAATCCATACGG
TAATGGTGATGCTAGTCAACAGATTGTTCAGATTTTGCGTGGGATTTAA

Upstream 100 bases:

>100_bases
GCTTACTTTAAAGCTAGTAAAAAAACATCAAATTAAAAAATTATATAATGATTAAGTGGTAGATTCTATTTCTACCGTTT
TAGATATTCGGGAGGTAATG

Downstream 100 bases:

>100_bases
GAAGATTCTCTAAAAGAGTCTAAGAGGAATCCACTCCACAAACATAAAACTCTTATGCTATCATTTATGATTGAGATAGA
CTCATAACTTAATATTTTTA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMVSPVLDLFGVVPDYDLEIMKANQTLFSITTSILEKIK
PVLEKEQPDIVLVHGDTTTTYAAALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKE
GRENVYVTGNTVIDALTTTVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRAVKRVLNEYEDVKVIYPIHKNPL
VRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMILTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEE
TIYQNFKLLLDDSGEYKKMSQASNPYGNGDASQQIVQILRGI

Sequences:

>Translated_362_residues
MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMVSPVLDLFGVVPDYDLEIMKANQTLFSITTSILEKIK
PVLEKEQPDIVLVHGDTTTTYAAALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKE
GRENVYVTGNTVIDALTTTVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRAVKRVLNEYEDVKVIYPIHKNPL
VRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMILTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEE
TIYQNFKLLLDDSGEYKKMSQASNPYGNGDASQQIVQILRGI
>Mature_362_residues
MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMVSPVLDLFGVVPDYDLEIMKANQTLFSITTSILEKIK
PVLEKEQPDIVLVHGDTTTTYAAALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKE
GRENVYVTGNTVIDALTTTVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRAVKRVLNEYEDVKVIYPIHKNPL
VRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMILTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEE
TIYQNFKLLLDDSGEYKKMSQASNPYGNGDASQQIVQILRGI

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=369, Percent_Identity=51.4905149051491, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40751; Mature: 40751

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMVSPVLDLFGVVPDYDLE
CCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEE
IMKANQTLFSITTSILEKIKPVLEKEQPDIVLVHGDTTTTYAAALAAFYLGIKVGHVEAG
EEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHEEEEEECC
LRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKEGRENVYVTGNTVIDALTTTV
CEEEECCCCCCHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
QEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRAVKRVLNEYEDVKVIYPIHKNPL
HHCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
VRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMILTDSGGVQEEAPSLGKPVLVMRDT
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEEECC
TERPEGVAAGTLKLVGTDEETIYQNFKLLLDDSGEYKKMSQASNPYGNGDASQQIVQILR
CCCCCCCEECEEEEEECCHHHHHHHHEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHH
GI
CC
>Mature Secondary Structure
MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMVSPVLDLFGVVPDYDLE
CCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEE
IMKANQTLFSITTSILEKIKPVLEKEQPDIVLVHGDTTTTYAAALAAFYLGIKVGHVEAG
EEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHEEEEEECC
LRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKEGRENVYVTGNTVIDALTTTV
CEEEECCCCCCHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
QEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRAVKRVLNEYEDVKVIYPIHKNPL
HHCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
VRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMILTDSGGVQEEAPSLGKPVLVMRDT
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEEECC
TERPEGVAAGTLKLVGTDEETIYQNFKLLLDDSGEYKKMSQASNPYGNGDASQQIVQILR
CCCCCCCEECEEEEEECCHHHHHHHHEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHH
GI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]