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The map label for this gene is rfbC [H]

Identifier: 169833448

GI number: 169833448

Start: 417278

End: 417871

Strand: Direct

Name: rfbC [H]

Synonym: SPH_0467

Alternate gene names: 169833448

Gene position: 417278-417871 (Clockwise)

Preceding gene: 169833959

Following gene: 169832836

Centisome position: 18.58

GC content: 43.43

Gene sequence:

>594_bases
ATGTCAGATAATTTTTTTGGAAAGACACTTGTGGTACGCAAGATTGATGCTATACCAGGACTGCTAGAGTTTGATATTCC
CGTTCATGGAGACAATCGTGGTTGGTTTAAGGAAAATTTCCAGAAGGAAAAGATGCTACCGCTTGGTTTTCCTGAAAGCT
TCTTTGCTGCAGGGAAACTGCAAAATAACGTCAGCTTTTCTCGCAAAAATGTTCTTCGAGGACTCCATGCTGAACCTTGG
GACAAGTATATCTCTGTTGCAGACGATGGGAAGGTTTTAGGATCTTGGGTAGATTTGCGTGAAGGCGAGACCTTTGGAAA
TGTTTACCAGACAGAGATTGATGCTAGCAAGGGAATTTTTGTCCCTCGTGGCGTAGCCAACGGTTTTCAAGTCCTCTCAG
ATACAGTTTCCTATAGCTATCTGGTCAATGACTACTGGGCTCTTGAACTCAAACCCAAATATGCCTTTGTTAACTATGCT
GACCCAGCATTGGGAATTGAGTGGGAAAACCTAGCGGAAGCTGAGGTTTCAGAGGCAGACAAACACCATCCTCTATTAAG
GGATGTCAAACCACTTACGAAAGACGAGTTGTAA

Upstream 100 bases:

>100_bases
TATGGGCTACATTAGTCGTGAAGACGTGCTGGAATTGGCTCAGCCTCTTAAGAAAAATGAATACGGACAATATTTGCTCC
GTTTGATTGGAGAAGCATAG

Downstream 100 bases:

>100_bases
AAGGAAACATTATGACTGAATACAAAAAAATTATCGTGACAGGTGGAGCTGGTTTTATCGGTTCTAACTTTGTTCACTAT
GTTTACAATAACTTTACAGA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAAGKLQNNVSFSRKNVLRGLHAEPW
DKYISVADDGKVLGSWVDLREGETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
DPALGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL

Sequences:

>Translated_197_residues
MSDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAAGKLQNNVSFSRKNVLRGLHAEPW
DKYISVADDGKVLGSWVDLREGETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
DPALGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL
>Mature_196_residues
SDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAAGKLQNNVSFSRKNVLRGLHAEPWD
KYISVADDGKVLGSWVDLREGETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYAD
PALGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=172, Percent_Identity=31.3953488372093, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17550412, Length=198, Percent_Identity=30.3030303030303, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 22288; Mature: 22157

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAAGKL
CCCCCCCHHHEEEECCCCCCEEEECCEEECCCCCCHHHCCCHHCCCCCCCCHHHHHHHHC
QNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREGETFGNVYQTEIDASKGIF
CCCCCHHHHHHHHCCCCCCHHHEEEECCCCCEEHHHHCCCCCCCCCCEEEEEECCCCCEE
VPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYADPALGIEWENLAEAEVSEAD
ECCCCCHHHHHHHHHHHHEEEECCEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHH
KHHPLLRDVKPLTKDEL
HCCCHHHHCCCCCCCCC
>Mature Secondary Structure 
SDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAAGKL
CCCCCCHHHEEEECCCCCCEEEECCEEECCCCCCHHHCCCHHCCCCCCCCHHHHHHHHC
QNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREGETFGNVYQTEIDASKGIF
CCCCCHHHHHHHHCCCCCCHHHEEEECCCCCEEHHHHCCCCCCCCCCEEEEEECCCCCEE
VPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYADPALGIEWENLAEAEVSEAD
ECCCCCHHHHHHHHHHHHEEEECCEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHH
KHHPLLRDVKPLTKDEL
HCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA