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The map label for this gene is hup [H]

Identifier: 169824180

GI number: 169824180

Start: 544336

End: 544626

Strand: Direct

Name: hup [H]

Synonym: FMG_0483

Alternate gene names: 169824180

Gene position: 544336-544626 (Clockwise)

Preceding gene: 169824179

Following gene: 169824181

Centisome position: 30.28

GC content: 30.93

Gene sequence:

>291_bases
ATGAATAAATCTGAATTATTATCAAGCATAGCTAAAAAAAGTGAGCTATCAAAAGTAGAAAGCGAAAGAGCTTTAAACGC
ATTCATTAAAACTGTTGAAGAAACATTAGCAAAAGGTGAAAAAGTACAATTAGTAGGATTTGGTACATTTGAATCAAGAG
AAAGAAAAGCTCGTGAAGGAAGAAACCCAAGAAATCCTGAAGAAAAAATTCAAATTCCTGCATCAAATGCGCCTGTATTT
AAAGCTGGTAAATCTTTAAAAGAAGCAGTTAACCAAAAAAAGAGTAAATAG

Upstream 100 bases:

>100_bases
AGGCTATTTTTTCAGTCAAAACACTTGAAATAAAAAAAATATTACTGTATACTGTATTTAAAATAGGTTTTAACTATTTT
GAAAATTTAAGGAGGAAAAG

Downstream 100 bases:

>100_bases
TTTATAAATCAGGCCAATCGGCCTGATTTTTTATTTATTAAATTTTTAATTATCAAAGAAAGATTGATTATGATTTACGA
TTTTTATATTAACAAAGATA

Product: DNA binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MNKSELLSSIAKKSELSKVESERALNAFIKTVEETLAKGEKVQLVGFGTFESRERKAREGRNPRNPEEKIQIPASNAPVF
KAGKSLKEAVNQKKSK

Sequences:

>Translated_96_residues
MNKSELLSSIAKKSELSKVESERALNAFIKTVEETLAKGEKVQLVGFGTFESRERKAREGRNPRNPEEKIQIPASNAPVF
KAGKSLKEAVNQKKSK
>Mature_96_residues
MNKSELLSSIAKKSELSKVESERALNAFIKTVEETLAKGEKVQLVGFGTFESRERKAREGRNPRNPEEKIQIPASNAPVF
KAGKSLKEAVNQKKSK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=91, Percent_Identity=52.7472527472528, Blast_Score=99, Evalue=7e-23,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=48.8888888888889, Blast_Score=90, Evalue=2e-20,
Organism=Escherichia coli, GI1787141, Length=92, Percent_Identity=34.7826086956522, Blast_Score=60, Evalue=2e-11,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10672; Mature: 10672

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSELLSSIAKKSELSKVESERALNAFIKTVEETLAKGEKVQLVGFGTFESRERKAREG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
RNPRNPEEKIQIPASNAPVFKAGKSLKEAVNQKKSK
CCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKSELLSSIAKKSELSKVESERALNAFIKTVEETLAKGEKVQLVGFGTFESRERKAREG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
RNPRNPEEKIQIPASNAPVFKAGKSLKEAVNQKKSK
CCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6540370 [H]