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The map label for this gene is prsA [H]

Identifier: 169824179

GI number: 169824179

Start: 543257

End: 544222

Strand: Direct

Name: prsA [H]

Synonym: FMG_0482

Alternate gene names: 169824179

Gene position: 543257-544222 (Clockwise)

Preceding gene: 169824178

Following gene: 169824180

Centisome position: 30.22

GC content: 30.64

Gene sequence:

>966_bases
ATGAAGAAATTTTTAGCAATTGTATTAGCTATGATGATGGTAATGGTAACAGCATGTTCTAACAAACCTAATGGAGCAGT
AGCTAAGATTGGAAAAGAATACATCTATCAAAAAGATGTAGACAAAGTTATGGAAGATTACAAACAATATTATGGACAAG
ATATTTTCAATCCTAACACTGAACAAGGCAAGGAAGCTTTGAAGCAAATCAAACCTAAAATCATTGATATGCTAATTAAC
GAAAAAATCGCAAACAAATTGATGAAAGATAAAAAAATCGAAGTGTCTGACAAGGAAGTTCAAGCAGAGGTTGATAAGCT
TCAAAAACAATTAGGTGGAGCAGACAAATTCAAAGAACAACTTAAGAAAGAAAACATGACAGAACAAGCTTTGAAAGAAC
AAATTGAAAAGCAATTGAAGAACAAGAAACTTTCTCAACAATTTGAAAAAGACTTCAAACCATCTGACAAAGAAATCAAA
GACGAATTTGACAAAAACATAGACACTTATACTCAATATAACGCAGATCACATTCTTTTCTCAGGAAAGGATGCTAAGGG
TAAAAATTTAGATGCTTCCAAGCTTAAAGCAAAATCAGAATTAGCTGACAAGACTTACGAAGAAGTAAAGAACGGCAAGA
ACTTCAATGAAGTTGCAAAAGCAAAATCAGAAGATCCATCAGCTAAGCAAAATTCTGGTAAATTAGGTGATTTCTTATCA
TCTACTATGGTAAAAGAATTTTCTGATGCATTAAAGAAAATGAAACCAGGTGAAGTTTCCAAACCAGTTAAAACAGAATT
TGGATATCACATCATTAAACTTAACAGTAAAGTTACTGAATTAGATAAGATGACTGATGCAAATAAACAAAACATTAAGA
CAGCAATTTCTAACAAAATTATCCAAGAAAAAGTTCAAAAAGAATTTGAAAAACAAAAAAAGGATTTGGGAGTAAAAATT
TACTAA

Upstream 100 bases:

>100_bases
AACCAAAAATTATTTTGGGATTTGAAGACAAAAATTTGAGAGATCCTATCGAAGTATTATCGATACTTTTGAAGGATAAT
GAGAAATAATTGGAGGAAAA

Downstream 100 bases:

>100_bases
TTTTTAATAAAAAAGGCTATTTTTTCAGTCAAAACACTTGAAATAAAAAAAATATTACTGTATACTGTATTTAAAATAGG
TTTTAACTATTTTGAAAATT

Product: putative peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKKFLAIVLAMMMVMVTACSNKPNGAVAKIGKEYIYQKDVDKVMEDYKQYYGQDIFNPNTEQGKEALKQIKPKIIDMLIN
EKIANKLMKDKKIEVSDKEVQAEVDKLQKQLGGADKFKEQLKKENMTEQALKEQIEKQLKNKKLSQQFEKDFKPSDKEIK
DEFDKNIDTYTQYNADHILFSGKDAKGKNLDASKLKAKSELADKTYEEVKNGKNFNEVAKAKSEDPSAKQNSGKLGDFLS
STMVKEFSDALKKMKPGEVSKPVKTEFGYHIIKLNSKVTELDKMTDANKQNIKTAISNKIIQEKVQKEFEKQKKDLGVKI
Y

Sequences:

>Translated_321_residues
MKKFLAIVLAMMMVMVTACSNKPNGAVAKIGKEYIYQKDVDKVMEDYKQYYGQDIFNPNTEQGKEALKQIKPKIIDMLIN
EKIANKLMKDKKIEVSDKEVQAEVDKLQKQLGGADKFKEQLKKENMTEQALKEQIEKQLKNKKLSQQFEKDFKPSDKEIK
DEFDKNIDTYTQYNADHILFSGKDAKGKNLDASKLKAKSELADKTYEEVKNGKNFNEVAKAKSEDPSAKQNSGKLGDFLS
STMVKEFSDALKKMKPGEVSKPVKTEFGYHIIKLNSKVTELDKMTDANKQNIKTAISNKIIQEKVQKEFEKQKKDLGVKI
Y
>Mature_321_residues
MKKFLAIVLAMMMVMVTACSNKPNGAVAKIGKEYIYQKDVDKVMEDYKQYYGQDIFNPNTEQGKEALKQIKPKIIDMLIN
EKIANKLMKDKKIEVSDKEVQAEVDKLQKQLGGADKFKEQLKKENMTEQALKEQIEKQLKNKKLSQQFEKDFKPSDKEIK
DEFDKNIDTYTQYNADHILFSGKDAKGKNLDASKLKAKSELADKTYEEVKNGKNFNEVAKAKSEDPSAKQNSGKLGDFLS
STMVKEFSDALKKMKPGEVSKPVKTEFGYHIIKLNSKVTELDKMTDANKQNIKTAISNKIIQEKVQKEFEKQKKDLGVKI
Y

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 36722; Mature: 36722

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLAIVLAMMMVMVTACSNKPNGAVAKIGKEYIYQKDVDKVMEDYKQYYGQDIFNPNT
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EQGKEALKQIKPKIIDMLINEKIANKLMKDKKIEVSDKEVQAEVDKLQKQLGGADKFKEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
LKKENMTEQALKEQIEKQLKNKKLSQQFEKDFKPSDKEIKDEFDKNIDTYTQYNADHILF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCEEEE
SGKDAKGKNLDASKLKAKSELADKTYEEVKNGKNFNEVAKAKSEDPSAKQNSGKLGDFLS
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHH
STMVKEFSDALKKMKPGEVSKPVKTEFGYHIIKLNSKVTELDKMTDANKQNIKTAISNKI
HHHHHHHHHHHHHCCCCCCCCCHHHHHCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHH
IQEKVQKEFEKQKKDLGVKIY
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKFLAIVLAMMMVMVTACSNKPNGAVAKIGKEYIYQKDVDKVMEDYKQYYGQDIFNPNT
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EQGKEALKQIKPKIIDMLINEKIANKLMKDKKIEVSDKEVQAEVDKLQKQLGGADKFKEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
LKKENMTEQALKEQIEKQLKNKKLSQQFEKDFKPSDKEIKDEFDKNIDTYTQYNADHILF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCEEEE
SGKDAKGKNLDASKLKAKSELADKTYEEVKNGKNFNEVAKAKSEDPSAKQNSGKLGDFLS
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHH
STMVKEFSDALKKMKPGEVSKPVKTEFGYHIIKLNSKVTELDKMTDANKQNIKTAISNKI
HHHHHHHHHHHHHCCCCCCCCCHHHHHCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHH
IQEKVQKEFEKQKKDLGVKIY
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]