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The map label for this gene is norM [H]

Identifier: 169824115

GI number: 169824115

Start: 474982

End: 476349

Strand: Direct

Name: norM [H]

Synonym: FMG_0418

Alternate gene names: 169824115

Gene position: 474982-476349 (Clockwise)

Preceding gene: 169824114

Following gene: 169824116

Centisome position: 26.42

GC content: 35.01

Gene sequence:

>1368_bases
ATGGGAAACAAAAAAAGCAATATTGAATTTATTACTAATGGAAATATTACTGATGTGATTTTTAAATTAAGTATCCCATT
GATGATTAGTAATCTAATCAAAACCCTTTATGGTATAACTGACGGAATATATGTAGCTCGAATTAGCTCGGAAGACTATG
CTGCGACATCTTTTACTTGGCCTGTGCTGTATTTGTTTATAGCAGTTGGACTGGGAGTAAGTGTTGCGGCTACTTCTTTA
ATGAGTCAAAGACTTGGAGCTAGAAAATTAAAAGACTGTTCAATATACGCTGTGCATACATTAATACTTACCACAGTACT
TGGAGTAATATTCAGTATACTCGGTCTAATCACAGCACCATTTATTGTCAGATGGATGGGGGCTAAAGGAAGCTTTGAAT
ATAAATCATACATATTCCTTGCGATAAATTCATTAGGACTATTGTTTGATATGATTTTTTTCGGATATCAATCGATACTA
AATTCTCAAGGAAGAACCAAATCGATGACGATTATATCGACAATTTCATCTGTGACAAACGTCGTTATCGATCCTTTCTT
CATTTTTGATAATGTTTTGGGAATTCCAGGTCTCAACATGGGACTTGCAGGTGCTGCATGGGCAACTGTTTTGTCGAAAG
TTTTACTGGTTGTATTTGCTGTAAGAGTTGTAAAAAAAGAATCCGAAATCGAAGTCAACTTCAAAAACTTCAAATTAGAT
ATGGGAATTATCAAACACATATTTTCCATCGCAATTCCAGCATCGCTTGGATCAAGTGGAGAAGCTATCGGGTTTACTGT
TCTTAATGGATTCATTCAATCATACGGCACAACGACACTCGCTGCATTTTCTATGGGCAACAGATTGTCCGATATATTCA
ATCAAGGAGCTATTGGAATTGGAATGGCTCTAACATCAATCACAGGTCAAAATATAGGGGCAGGTAAAAAGGAAAGAAGC
AAAAGCATTTTTAAACGCGCAAATATAATCATAACATTCTTCTCACTTGCATCTGCTATAATTATTTTACTTTTCAAAGA
CCAATTATTATCTGTGTTTATCAAAGACCGTAGTGATATTGAACTTTGGAGACAAGCTAGTGAGTACATGTACTTCTCAG
CTATAATTACATTTTTCATGGGATATTTCTCAGCGATTAATGGTTTCTTCCAAGGTGTTGGAAAAACAAAACTTACAATG
TATTTGTCACTTGCGAGATTGTGGGCTCTACGACTTCCACTTATTATGATACTTAAGAGTTTGACAAATCTCGGTTCTAC
AGGAATTTGGATTTCGATGTTAGTATCCAATGGACTTACAGTTCTGATAGGATTTATAATATACAAACAAGGACAATGGG
AAAGATAA

Upstream 100 bases:

>100_bases
TATTATGAAGGACAAATTGCACCTACATTGAGTATTCACACTGGACCAGGATTATTTGGAATAGGTTATTTTAAATTATA
AATTAATAGGGGGCGAGTAA

Downstream 100 bases:

>100_bases
GACTGATGTTAAACATCGGTCTTTTTTTATTGAAATATTCTATATATTTCAAAATTGAAATAATTTATGAAAATTTATAA
AATAAATAAAAGCTCAAAAA

Product: putative DNA damage-inducible protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MGNKKSNIEFITNGNITDVIFKLSIPLMISNLIKTLYGITDGIYVARISSEDYAATSFTWPVLYLFIAVGLGVSVAATSL
MSQRLGARKLKDCSIYAVHTLILTTVLGVIFSILGLITAPFIVRWMGAKGSFEYKSYIFLAINSLGLLFDMIFFGYQSIL
NSQGRTKSMTIISTISSVTNVVIDPFFIFDNVLGIPGLNMGLAGAAWATVLSKVLLVVFAVRVVKKESEIEVNFKNFKLD
MGIIKHIFSIAIPASLGSSGEAIGFTVLNGFIQSYGTTTLAAFSMGNRLSDIFNQGAIGIGMALTSITGQNIGAGKKERS
KSIFKRANIIITFFSLASAIIILLFKDQLLSVFIKDRSDIELWRQASEYMYFSAIITFFMGYFSAINGFFQGVGKTKLTM
YLSLARLWALRLPLIMILKSLTNLGSTGIWISMLVSNGLTVLIGFIIYKQGQWER

Sequences:

>Translated_455_residues
MGNKKSNIEFITNGNITDVIFKLSIPLMISNLIKTLYGITDGIYVARISSEDYAATSFTWPVLYLFIAVGLGVSVAATSL
MSQRLGARKLKDCSIYAVHTLILTTVLGVIFSILGLITAPFIVRWMGAKGSFEYKSYIFLAINSLGLLFDMIFFGYQSIL
NSQGRTKSMTIISTISSVTNVVIDPFFIFDNVLGIPGLNMGLAGAAWATVLSKVLLVVFAVRVVKKESEIEVNFKNFKLD
MGIIKHIFSIAIPASLGSSGEAIGFTVLNGFIQSYGTTTLAAFSMGNRLSDIFNQGAIGIGMALTSITGQNIGAGKKERS
KSIFKRANIIITFFSLASAIIILLFKDQLLSVFIKDRSDIELWRQASEYMYFSAIITFFMGYFSAINGFFQGVGKTKLTM
YLSLARLWALRLPLIMILKSLTNLGSTGIWISMLVSNGLTVLIGFIIYKQGQWER
>Mature_454_residues
GNKKSNIEFITNGNITDVIFKLSIPLMISNLIKTLYGITDGIYVARISSEDYAATSFTWPVLYLFIAVGLGVSVAATSLM
SQRLGARKLKDCSIYAVHTLILTTVLGVIFSILGLITAPFIVRWMGAKGSFEYKSYIFLAINSLGLLFDMIFFGYQSILN
SQGRTKSMTIISTISSVTNVVIDPFFIFDNVLGIPGLNMGLAGAAWATVLSKVLLVVFAVRVVKKESEIEVNFKNFKLDM
GIIKHIFSIAIPASLGSSGEAIGFTVLNGFIQSYGTTTLAAFSMGNRLSDIFNQGAIGIGMALTSITGQNIGAGKKERSK
SIFKRANIIITFFSLASAIIILLFKDQLLSVFIKDRSDIELWRQASEYMYFSAIITFFMGYFSAINGFFQGVGKTKLTMY
LSLARLWALRLPLIMILKSLTNLGSTGIWISMLVSNGLTVLIGFIIYKQGQWER

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=452, Percent_Identity=21.0176991150442, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49964; Mature: 49833

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNKKSNIEFITNGNITDVIFKLSIPLMISNLIKTLYGITDGIYVARISSEDYAATSFTW
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHH
PVLYLFIAVGLGVSVAATSLMSQRLGARKLKDCSIYAVHTLILTTVLGVIFSILGLITAP
HHHHHHHHHHCCHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVRWMGAKGSFEYKSYIFLAINSLGLLFDMIFFGYQSILNSQGRTKSMTIISTISSVTN
HHHHHHCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VVIDPFFIFDNVLGIPGLNMGLAGAAWATVLSKVLLVVFAVRVVKKESEIEVNFKNFKLD
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHEEEH
MGIIKHIFSIAIPASLGSSGEAIGFTVLNGFIQSYGTTTLAAFSMGNRLSDIFNQGAIGI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHCCCCHHH
GMALTSITGQNIGAGKKERSKSIFKRANIIITFFSLASAIIILLFKDQLLSVFIKDRSDI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELWRQASEYMYFSAIITFFMGYFSAINGFFQGVGKTKLTMYLSLARLWALRLPLIMILKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTNLGSTGIWISMLVSNGLTVLIGFIIYKQGQWER
HHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GNKKSNIEFITNGNITDVIFKLSIPLMISNLIKTLYGITDGIYVARISSEDYAATSFTW
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHH
PVLYLFIAVGLGVSVAATSLMSQRLGARKLKDCSIYAVHTLILTTVLGVIFSILGLITAP
HHHHHHHHHHCCHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVRWMGAKGSFEYKSYIFLAINSLGLLFDMIFFGYQSILNSQGRTKSMTIISTISSVTN
HHHHHHCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VVIDPFFIFDNVLGIPGLNMGLAGAAWATVLSKVLLVVFAVRVVKKESEIEVNFKNFKLD
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHEEEH
MGIIKHIFSIAIPASLGSSGEAIGFTVLNGFIQSYGTTTLAAFSMGNRLSDIFNQGAIGI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHCCCCHHH
GMALTSITGQNIGAGKKERSKSIFKRANIIITFFSLASAIIILLFKDQLLSVFIKDRSDI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELWRQASEYMYFSAIITFFMGYFSAINGFFQGVGKTKLTMYLSLARLWALRLPLIMILKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTNLGSTGIWISMLVSNGLTVLIGFIIYKQGQWER
HHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]