Click here to switch to the map view.

The map label for this gene is norM [H]

Identifier: 169824110

GI number: 169824110

Start: 468994

End: 470391

Strand: Direct

Name: norM [H]

Synonym: FMG_0413

Alternate gene names: 169824110

Gene position: 468994-470391 (Clockwise)

Preceding gene: 169824109

Following gene: 169824111

Centisome position: 26.09

GC content: 33.05

Gene sequence:

>1398_bases
TTGAATTTAGCATTAAAGAAGAGTAAATTTTTCGGGGACAAAAATTTCTACAAAGGTGTGTTGGTACTAGCAATTCCTAT
CATTATTCAGCAACTTATTACATCTTTTGTAAATATGCTGGACAATATTATGGTTGGACAGACTGGAACTTTTGCAATGA
GTGGGGTTTCTGTTGCAAATCAATTGATTACTGTATTTAACTTGGCGATTTTCGGCCTGGTATCAGCGGCGAGTATTTTT
GCAGCACAATTTGCAGGGAAAAAAGATTACAAGAATGTGCAAAACTGTTTGTATTTTGATGTGGTGTTATCTTTTATTGT
TTCTGTGATTAGTGTGCTTATTTTCTGGGTTTTTGGAGAGAAATTATTATATTTATTTATGAATCCAGACACAGATACTG
CAAAAAATATTGCCACGACTATGGAATTTGCGCTAGATTATACAAAAATAATGACAATAGGATTTATTCCATTTGCTTTT
TCACAGTCGATTTCATCTTCAATGAGGGTAAATGGAGAGACAAGACTTCCTATGATTACAAGTGTGATTACGGTGTTAGT
GAACTTCGTGTTCAATTTGGTTTTGATTTTCGGACTTTTAGGTTTTCCTACATTAGGACCCAAAGGTGCTGCGATTGCGA
CTGTTATTTCGAGATTTGTGGAACTATCGTTGTTTATTTATTTTGCAAACAAAAACAAGTTTAGATTCACATTTTATTCT
GATTTCTTCAAGAATTTTCACATAGACACTCATCTTTTCAAAAATATAACTGTTGCAGGAATTCCTTTGATTATAAATGA
AGTTTTGTATTCTTTGGGGATTGCTGCGATTACACAATCTTATTCTACAAGAGGAATTGAAGCTTTGGCAGCATATAATA
TTTCCCAGACAATTATAGGACTTTTCATCGTGTTTAATTTGGCGATGGGAGATTGTATTTCAATTATGGTAGGAAGACTT
TTGGGAAGTGGAAATATCGATGAAGCTGTTGACACTGACAGAAAATTAGTCGTGTTCTCATTTATGTTAGCAGTTGTAGT
TGGAATTGTGTTGATTATTTTGGCACCACTTTTTCCAGAATTTTACAACACAACTAATGATGTAAAATTAATGGCGACGA
ATATGCTTAGAGTTGGTGGAGCGTTTTTGTGGATTTCTGCTTTGTACAATGCGTCATATTTTACACTCAGAAGTGGTGGT
AAAACTATTTTGACTTTGCTTTTTGATTCGGTGGGAATTGTTTTGATTTCGTATCCGTTTTCGTTTTTATTGGCAAAATT
TACAGATTTAAATGTCGTATTGATGTATTTGATAATTTCTGTGATTGATTTATACAAGGTTATTTTGGGATTGATTTTAG
TTGGAAAGAAAATTTGGGTAAAAAATTTGGCGAAATAA

Upstream 100 bases:

>100_bases
TGTGGGTTCAAATTTTATAGTAAACATTTGTATCAAAATTTTGATGGAACAAACAAACTTTGCAATTATTATTATATAGA
AAATTTGAAGGAGGGATAGA

Downstream 100 bases:

>100_bases
TTGCCAGATTTGTATTAATAAATGTGAGATTTGGCGATTTGTGATATAATAAAATAAGTTAAATTTATTTTTTATGGGGG
ATATTATGAGTGAAGTAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNLALKKSKFFGDKNFYKGVLVLAIPIIIQQLITSFVNMLDNIMVGQTGTFAMSGVSVANQLITVFNLAIFGLVSAASIF
AAQFAGKKDYKNVQNCLYFDVVLSFIVSVISVLIFWVFGEKLLYLFMNPDTDTAKNIATTMEFALDYTKIMTIGFIPFAF
SQSISSSMRVNGETRLPMITSVITVLVNFVFNLVLIFGLLGFPTLGPKGAAIATVISRFVELSLFIYFANKNKFRFTFYS
DFFKNFHIDTHLFKNITVAGIPLIINEVLYSLGIAAITQSYSTRGIEALAAYNISQTIIGLFIVFNLAMGDCISIMVGRL
LGSGNIDEAVDTDRKLVVFSFMLAVVVGIVLIILAPLFPEFYNTTNDVKLMATNMLRVGGAFLWISALYNASYFTLRSGG
KTILTLLFDSVGIVLISYPFSFLLAKFTDLNVVLMYLIISVIDLYKVILGLILVGKKIWVKNLAK

Sequences:

>Translated_465_residues
MNLALKKSKFFGDKNFYKGVLVLAIPIIIQQLITSFVNMLDNIMVGQTGTFAMSGVSVANQLITVFNLAIFGLVSAASIF
AAQFAGKKDYKNVQNCLYFDVVLSFIVSVISVLIFWVFGEKLLYLFMNPDTDTAKNIATTMEFALDYTKIMTIGFIPFAF
SQSISSSMRVNGETRLPMITSVITVLVNFVFNLVLIFGLLGFPTLGPKGAAIATVISRFVELSLFIYFANKNKFRFTFYS
DFFKNFHIDTHLFKNITVAGIPLIINEVLYSLGIAAITQSYSTRGIEALAAYNISQTIIGLFIVFNLAMGDCISIMVGRL
LGSGNIDEAVDTDRKLVVFSFMLAVVVGIVLIILAPLFPEFYNTTNDVKLMATNMLRVGGAFLWISALYNASYFTLRSGG
KTILTLLFDSVGIVLISYPFSFLLAKFTDLNVVLMYLIISVIDLYKVILGLILVGKKIWVKNLAK
>Mature_465_residues
MNLALKKSKFFGDKNFYKGVLVLAIPIIIQQLITSFVNMLDNIMVGQTGTFAMSGVSVANQLITVFNLAIFGLVSAASIF
AAQFAGKKDYKNVQNCLYFDVVLSFIVSVISVLIFWVFGEKLLYLFMNPDTDTAKNIATTMEFALDYTKIMTIGFIPFAF
SQSISSSMRVNGETRLPMITSVITVLVNFVFNLVLIFGLLGFPTLGPKGAAIATVISRFVELSLFIYFANKNKFRFTFYS
DFFKNFHIDTHLFKNITVAGIPLIINEVLYSLGIAAITQSYSTRGIEALAAYNISQTIIGLFIVFNLAMGDCISIMVGRL
LGSGNIDEAVDTDRKLVVFSFMLAVVVGIVLIILAPLFPEFYNTTNDVKLMATNMLRVGGAFLWISALYNASYFTLRSGG
KTILTLLFDSVGIVLISYPFSFLLAKFTDLNVVLMYLIISVIDLYKVILGLILVGKKIWVKNLAK

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=364, Percent_Identity=23.9010989010989, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994890, Length=350, Percent_Identity=22.8571428571429, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51460; Mature: 51460

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLALKKSKFFGDKNFYKGVLVLAIPIIIQQLITSFVNMLDNIMVGQTGTFAMSGVSVAN
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QLITVFNLAIFGLVSAASIFAAQFAGKKDYKNVQNCLYFDVVLSFIVSVISVLIFWVFGE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLYLFMNPDTDTAKNIATTMEFALDYTKIMTIGFIPFAFSQSISSSMRVNGETRLPMIT
HHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
SVITVLVNFVFNLVLIFGLLGFPTLGPKGAAIATVISRFVELSLFIYFANKNKFRFTFYS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCEEEEEEHH
DFFKNFHIDTHLFKNITVAGIPLIINEVLYSLGIAAITQSYSTRGIEALAAYNISQTIIG
HHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LFIVFNLAMGDCISIMVGRLLGSGNIDEAVDTDRKLVVFSFMLAVVVGIVLIILAPLFPE
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FYNTTNDVKLMATNMLRVGGAFLWISALYNASYFTLRSGGKTILTLLFDSVGIVLISYPF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
SFLLAKFTDLNVVLMYLIISVIDLYKVILGLILVGKKIWVKNLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLALKKSKFFGDKNFYKGVLVLAIPIIIQQLITSFVNMLDNIMVGQTGTFAMSGVSVAN
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QLITVFNLAIFGLVSAASIFAAQFAGKKDYKNVQNCLYFDVVLSFIVSVISVLIFWVFGE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLYLFMNPDTDTAKNIATTMEFALDYTKIMTIGFIPFAFSQSISSSMRVNGETRLPMIT
HHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
SVITVLVNFVFNLVLIFGLLGFPTLGPKGAAIATVISRFVELSLFIYFANKNKFRFTFYS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCEEEEEEHH
DFFKNFHIDTHLFKNITVAGIPLIINEVLYSLGIAAITQSYSTRGIEALAAYNISQTIIG
HHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LFIVFNLAMGDCISIMVGRLLGSGNIDEAVDTDRKLVVFSFMLAVVVGIVLIILAPLFPE
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FYNTTNDVKLMATNMLRVGGAFLWISALYNASYFTLRSGGKTILTLLFDSVGIVLISYPF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
SFLLAKFTDLNVVLMYLIISVIDLYKVILGLILVGKKIWVKNLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]