Click here to switch to the map view.

The map label for this gene is udp [H]

Identifier: 169824088

GI number: 169824088

Start: 448478

End: 449251

Strand: Direct

Name: udp [H]

Synonym: FMG_0391

Alternate gene names: 169824088

Gene position: 448478-449251 (Clockwise)

Preceding gene: 169824087

Following gene: 169824091

Centisome position: 24.95

GC content: 36.56

Gene sequence:

>774_bases
ATGAAATACGCAGAAGAAGGCGTTCAATATCATTTGAATATTAAAAGTGGAGATGTGGGTAAGTATGTTATACTACCTGG
AGATCCAAAAAGATGCGAAAAGATTGCAAAATATTTTGATGATGCAAAACTAATTGCAGATCATAGAGAATATGTAACTT
ACACTGGAACTTTAAATGGAGAAAAAGTATCCGTAACAAGCACTGGAATCGGAGGTCCTTCTGCAGCAATTGCGATGGAA
GAACTTGTCAAAGCAGGTGCAGATACTTTTATAAGAGTTGGAACTTGTGGTGGAATTCAAGAAGATGTCAAAAGTTCTGA
TGTAGTTATAGCAAATTCTGCGATAAGAGCTGAAGGGACTACGAAGGAATATGCTCCGATAGAATTTCCAGCAGTCGCAA
ATTTAGATGTGACAAATTCTTTGGTAAAAGCTTCGAAAAATTTGGGACATAATTATCACGTTGGAGTTGTTCAATGTAAA
GACAGCTTCTACGGTCAACATGAACCAGAAAAAATGCCTGTGTCTTACGATTTGTTAAACAAATGGGAAGCTTGGAAAAG
GCTTGGAACATTGGCAAGTGAGATGGAATCTGCAGCACTTTTTGTAGTTGCAAGTTATCTTCATGTTAGATGTGGATCTT
GTTTTTTGGTTGTAGCAAATCAAGAACGTGAGAAGAAACACTTGGATAATCCTGTGTGCCACGACACTGATGTAGCCATT
AAAGTTGCAATAGAAGCAATCAAAAATTTAATAGAAGAAGATAAACGAAAATAA

Upstream 100 bases:

>100_bases
ATTAATTTATCGCACAAATTACGTCAAAATCCACGCTGAATAATGATATTTATCTAAAATTAGTATATACTAATAATATA
GATAAAAATGAGGTGATTTT

Downstream 100 bases:

>100_bases
ATGTCGAAATTATGATTTTAAAATTTTGACAAATAATATTCAAGGTGATATAATAAAAATAGTTAATAACGTTTTCATTT
TATCCATTTTAAATGGGTAT

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKYAEEGVQYHLNIKSGDVGKYVILPGDPKRCEKIAKYFDDAKLIADHREYVTYTGTLNGEKVSVTSTGIGGPSAAIAME
ELVKAGADTFIRVGTCGGIQEDVKSSDVVIANSAIRAEGTTKEYAPIEFPAVANLDVTNSLVKASKNLGHNYHVGVVQCK
DSFYGQHEPEKMPVSYDLLNKWEAWKRLGTLASEMESAALFVVASYLHVRCGSCFLVVANQEREKKHLDNPVCHDTDVAI
KVAIEAIKNLIEEDKRK

Sequences:

>Translated_257_residues
MKYAEEGVQYHLNIKSGDVGKYVILPGDPKRCEKIAKYFDDAKLIADHREYVTYTGTLNGEKVSVTSTGIGGPSAAIAME
ELVKAGADTFIRVGTCGGIQEDVKSSDVVIANSAIRAEGTTKEYAPIEFPAVANLDVTNSLVKASKNLGHNYHVGVVQCK
DSFYGQHEPEKMPVSYDLLNKWEAWKRLGTLASEMESAALFVVASYLHVRCGSCFLVVANQEREKKHLDNPVCHDTDVAI
KVAIEAIKNLIEEDKRK
>Mature_257_residues
MKYAEEGVQYHLNIKSGDVGKYVILPGDPKRCEKIAKYFDDAKLIADHREYVTYTGTLNGEKVSVTSTGIGGPSAAIAME
ELVKAGADTFIRVGTCGGIQEDVKSSDVVIANSAIRAEGTTKEYAPIEFPAVANLDVTNSLVKASKNLGHNYHVGVVQCK
DSFYGQHEPEKMPVSYDLLNKWEAWKRLGTLASEMESAALFVVASYLHVRCGSCFLVVANQEREKKHLDNPVCHDTDVAI
KVAIEAIKNLIEEDKRK

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=247, Percent_Identity=36.8421052631579, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1790844, Length=198, Percent_Identity=34.8484848484849, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 28196; Mature: 28196

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAEEGVQYHLNIKSGDVGKYVILPGDPKRCEKIAKYFDDAKLIADHREYVTYTGTLNG
CCCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCHHHHCCCCEEEEEEECCCC
EKVSVTSTGIGGPSAAIAMEELVKAGADTFIRVGTCGGIQEDVKSSDVVIANSAIRAEGT
CEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCEEEECCEEECCCC
TKEYAPIEFPAVANLDVTNSLVKASKNLGHNYHVGVVQCKDSFYGQHEPEKMPVSYDLLN
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHH
KWEAWKRLGTLASEMESAALFVVASYLHVRCGSCFLVVANQEREKKHLDNPVCHDTDVAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCCCCCCHHH
KVAIEAIKNLIEEDKRK
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYAEEGVQYHLNIKSGDVGKYVILPGDPKRCEKIAKYFDDAKLIADHREYVTYTGTLNG
CCCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCHHHHCCCCEEEEEEECCCC
EKVSVTSTGIGGPSAAIAMEELVKAGADTFIRVGTCGGIQEDVKSSDVVIANSAIRAEGT
CEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCEEEECCEEECCCC
TKEYAPIEFPAVANLDVTNSLVKASKNLGHNYHVGVVQCKDSFYGQHEPEKMPVSYDLLN
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHH
KWEAWKRLGTLASEMESAALFVVASYLHVRCGSCFLVVANQEREKKHLDNPVCHDTDVAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCCCCCCHHH
KVAIEAIKNLIEEDKRK
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]