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The map label for this gene is mhpA [H]

Identifier: 169629659

GI number: 169629659

Start: 2616886

End: 2618442

Strand: Reverse

Name: mhpA [H]

Synonym: MAB_2573c

Alternate gene names: 169629659

Gene position: 2618442-2616886 (Counterclockwise)

Preceding gene: 169629660

Following gene: 169629658

Centisome position: 51.67

GC content: 64.87

Gene sequence:

>1557_bases
GTGAACGCCTCAGCACAGCTGTCGTTTCCGGTTGTCATCATCGGCGCGGGACCAACCGGCGTCACCGCCGCGACGCTGTT
GGCTCAGCACGGCGTGCAGTGCCTGCTCCTTGAGCGGTGGGCCACGGTGTACCCCCAGCCGCGGGCAGTGCATCTGGACG
ACGAGATCTACCGCATTCTGGCCCAGCTGGGCATCGCCGAGCAGTTCGCCACCATCTCCCGGCCCGGCGCCGGCATGCGG
TTGCTCGATCACCGCGGGCAGATCCTGAGCCAGATCGCACGCGCCCCGATCGGCACGCATGGATACCCGCAAGCCAACAT
GTTCGACCAGCCCGAACTCGAGCAGCTGCTGCGCGCCAACCTCACCAACTATCCGCAGGTCTCGTTGCGCGGCGGCGTCG
AAGTCACGACCATCGCACACATCAGCGCCAGTCAGGTGCAGGTGACGTTCACCGACCGTGACAGCGGCGACGAGCACAAG
GTCACAGCAACCTACGTACTCGGCTGCGACGGCGCCAACAGCGTGGTCAGGGCCGCGATCGGCGCCAGCATGACGGCGCG
GCGATTCGCGCAACGATGGCTCGTGGTCGACCTGAACACCGACGCCGACCTAGGCCACTGGGACGGCGTGCACCACCTGT
GCGACCCAGACCGAGCGACCACATTCATGCGAGTCGGGGAACGTCGCTATCGCTGGGAATTCAAACTGCACCCCGGCGAG
ACCGCCGCAGACTACGACACCGTCGAGAAACTGCGACCACTGATCGCTGTCTGGACGGGTGCGAGCGCGATCAGCGAGCT
GACCCTGATTCGGGTCACCGAATACACCTTCCGTGCCCACGTCGCCAGCCACTGGCGTGATCGCAATGTGTTCATTCTCG
GCGATGCCGCTCACCTGACACCGCCGTTCGTGGGACAAGGCATGGGGGCTGGAATCAGAGACGCGGCCAATCTCACCTGG
AAACTGGCCGGAGTACTCGACGGCCAGCTGCCTACACGCGTGCTGGATACCTACGAACAAGAACGAAAACCGCACGCCTG
GAAAATGATCACCATCGCACTGGCCGTTGGAGCGGCTATGACCGCCCGCGGCACAGCTGCCACGGCTATACGGAACCTGC
TTGTTCCACGCCTGCAGTACATCCCAGGGCTACGGTCGCGGATACAGCACTCAGGCACGCCAGCCCTCACACGGTCTGCA
CTGGTGAACAAGACCCCACGCTGCCGACAACTAGCTGGCACACAGATCCCTAATCTTGTTCTGAGCCAAGGCCATCGGAT
CGACACCTTATTGGGCAGCGGGTTCGCGCTCGTCGCCTCCGAAACCGTCGACGCCGATCAGCAAGCACAGCTGCGTCGGC
GCGGCGCAGCCATCATCGTCGAACCCCGCGGATCCGAGCTCGATCGATGGCTGCGCCGCGGCGGTGCCCGCGCGGCCCTG
ATCCGCCCCGACCGCACCGTCATGCAGACGGCCCGCAGCCCCAGCCAGATAGCTTTCACCACAACGCTATTTGCCCCAAC
CCACCAGCCCGCCCCTACCTACCGGGAGACCCCATGA

Upstream 100 bases:

>100_bases
CCGTCACCGCGATGGTGACCGTCGGCGAGGACGCTGACACTACCGCCATCCAGACAATCCTCGACTGCTACGCGGTCACT
GCGCAGATCCGGCGCCCGTC

Downstream 100 bases:

>100_bases
AACACCGCACCGAAAGGTCTCGGTTATGAGTCGACGCAAACAACCAAGAGGGCAAGCCGGCCGAATTCTGGGCGCGTTGT
GGATGCCCCTGGTGGCGCTG

Product: 3-(3-hydroxyphenyl)propionate hydroxylase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MNASAQLSFPVVIIGAGPTGVTAATLLAQHGVQCLLLERWATVYPQPRAVHLDDEIYRILAQLGIAEQFATISRPGAGMR
LLDHRGQILSQIARAPIGTHGYPQANMFDQPELEQLLRANLTNYPQVSLRGGVEVTTIAHISASQVQVTFTDRDSGDEHK
VTATYVLGCDGANSVVRAAIGASMTARRFAQRWLVVDLNTDADLGHWDGVHHLCDPDRATTFMRVGERRYRWEFKLHPGE
TAADYDTVEKLRPLIAVWTGASAISELTLIRVTEYTFRAHVASHWRDRNVFILGDAAHLTPPFVGQGMGAGIRDAANLTW
KLAGVLDGQLPTRVLDTYEQERKPHAWKMITIALAVGAAMTARGTAATAIRNLLVPRLQYIPGLRSRIQHSGTPALTRSA
LVNKTPRCRQLAGTQIPNLVLSQGHRIDTLLGSGFALVASETVDADQQAQLRRRGAAIIVEPRGSELDRWLRRGGARAAL
IRPDRTVMQTARSPSQIAFTTTLFAPTHQPAPTYRETP

Sequences:

>Translated_518_residues
MNASAQLSFPVVIIGAGPTGVTAATLLAQHGVQCLLLERWATVYPQPRAVHLDDEIYRILAQLGIAEQFATISRPGAGMR
LLDHRGQILSQIARAPIGTHGYPQANMFDQPELEQLLRANLTNYPQVSLRGGVEVTTIAHISASQVQVTFTDRDSGDEHK
VTATYVLGCDGANSVVRAAIGASMTARRFAQRWLVVDLNTDADLGHWDGVHHLCDPDRATTFMRVGERRYRWEFKLHPGE
TAADYDTVEKLRPLIAVWTGASAISELTLIRVTEYTFRAHVASHWRDRNVFILGDAAHLTPPFVGQGMGAGIRDAANLTW
KLAGVLDGQLPTRVLDTYEQERKPHAWKMITIALAVGAAMTARGTAATAIRNLLVPRLQYIPGLRSRIQHSGTPALTRSA
LVNKTPRCRQLAGTQIPNLVLSQGHRIDTLLGSGFALVASETVDADQQAQLRRRGAAIIVEPRGSELDRWLRRGGARAAL
IRPDRTVMQTARSPSQIAFTTTLFAPTHQPAPTYRETP
>Mature_518_residues
MNASAQLSFPVVIIGAGPTGVTAATLLAQHGVQCLLLERWATVYPQPRAVHLDDEIYRILAQLGIAEQFATISRPGAGMR
LLDHRGQILSQIARAPIGTHGYPQANMFDQPELEQLLRANLTNYPQVSLRGGVEVTTIAHISASQVQVTFTDRDSGDEHK
VTATYVLGCDGANSVVRAAIGASMTARRFAQRWLVVDLNTDADLGHWDGVHHLCDPDRATTFMRVGERRYRWEFKLHPGE
TAADYDTVEKLRPLIAVWTGASAISELTLIRVTEYTFRAHVASHWRDRNVFILGDAAHLTPPFVGQGMGAGIRDAANLTW
KLAGVLDGQLPTRVLDTYEQERKPHAWKMITIALAVGAAMTARGTAATAIRNLLVPRLQYIPGLRSRIQHSGTPALTRSA
LVNKTPRCRQLAGTQIPNLVLSQGHRIDTLLGSGFALVASETVDADQQAQLRRRGAAIIVEPRGSELDRWLRRGGARAAL
IRPDRTVMQTARSPSQIAFTTTLFAPTHQPAPTYRETP

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=539, Percent_Identity=26.9016697588126, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 56748; Mature: 56748

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASAQLSFPVVIIGAGPTGVTAATLLAQHGVQCLLLERWATVYPQPRAVHLDDEIYRIL
CCCCCEECCCEEEEECCCCCHHHHHHHHHCCCCEEEEHHHHHHCCCCCEEECCHHHHHHH
AQLGIAEQFATISRPGAGMRLLDHRGQILSQIARAPIGTHGYPQANMFDQPELEQLLRAN
HHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHC
LTNYPQVSLRGGVEVTTIAHISASQVQVTFTDRDSGDEHKVTATYVLGCDGANSVVRAAI
CCCCCCEEECCCEEEEEEEEEECCEEEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHH
GASMTARRFAQRWLVVDLNTDADLGHWDGVHHLCDPDRATTFMRVGERRYRWEFKLHPGE
CCHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCC
TAADYDTVEKLRPLIAVWTGASAISELTLIRVTEYTFRAHVASHWRDRNVFILGDAAHLT
CCCHHHHHHHHHHHHEEECCHHHHHHEEEEEEEHHHHHHHHHHHCCCCCEEEEECHHHCC
PPFVGQGMGAGIRDAANLTWKLAGVLDGQLPTRVLDTYEQERKPHAWKMITIALAVGAAM
CCCCCCCCCCCCCHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TARGTAATAIRNLLVPRLQYIPGLRSRIQHSGTPALTRSALVNKTPRCRQLAGTQIPNLV
HCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHH
LSQGHRIDTLLGSGFALVASETVDADQQAQLRRRGAAIIVEPRGSELDRWLRRGGARAAL
HHCCCEEEHHHCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCEEEE
IRPDRTVMQTARSPSQIAFTTTLFAPTHQPAPTYRETP
ECCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNASAQLSFPVVIIGAGPTGVTAATLLAQHGVQCLLLERWATVYPQPRAVHLDDEIYRIL
CCCCCEECCCEEEEECCCCCHHHHHHHHHCCCCEEEEHHHHHHCCCCCEEECCHHHHHHH
AQLGIAEQFATISRPGAGMRLLDHRGQILSQIARAPIGTHGYPQANMFDQPELEQLLRAN
HHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHC
LTNYPQVSLRGGVEVTTIAHISASQVQVTFTDRDSGDEHKVTATYVLGCDGANSVVRAAI
CCCCCCEEECCCEEEEEEEEEECCEEEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHH
GASMTARRFAQRWLVVDLNTDADLGHWDGVHHLCDPDRATTFMRVGERRYRWEFKLHPGE
CCHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCC
TAADYDTVEKLRPLIAVWTGASAISELTLIRVTEYTFRAHVASHWRDRNVFILGDAAHLT
CCCHHHHHHHHHHHHEEECCHHHHHHEEEEEEEHHHHHHHHHHHCCCCCEEEEECHHHCC
PPFVGQGMGAGIRDAANLTWKLAGVLDGQLPTRVLDTYEQERKPHAWKMITIALAVGAAM
CCCCCCCCCCCCCHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TARGTAATAIRNLLVPRLQYIPGLRSRIQHSGTPALTRSALVNKTPRCRQLAGTQIPNLV
HCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHH
LSQGHRIDTLLGSGFALVASETVDADQQAQLRRRGAAIIVEPRGSELDRWLRRGGARAAL
HHCCCEEEHHHCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCEEEE
IRPDRTVMQTARSPSQIAFTTTLFAPTHQPAPTYRETP
ECCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA