Click here to switch to the map view.

The map label for this gene is ntcA [H]

Identifier: 169629592

GI number: 169629592

Start: 2561868

End: 2562566

Strand: Reverse

Name: ntcA [H]

Synonym: MAB_2506c

Alternate gene names: 169629592

Gene position: 2562566-2561868 (Counterclockwise)

Preceding gene: 169629595

Following gene: 169629591

Centisome position: 50.57

GC content: 63.81

Gene sequence:

>699_bases
GTGCACAGTGCGGTCGAGGAAACGCCAGTGTTTCGCGGCATGAGCACGCCCGCGGTGGCGGCAGCCACTGCGCGTCTGAC
CACCGAGCATTTTCAGCCGGACGAGGTGATATTCCGTCCGGGGGACCCCGGTGACCGCATGTATCTGGTCACCCAGGGAA
AGGTGGCACTGAGCAGGCGGTCGGGCGATGGCGCCGAGCGTCTTGCCACCTTGGTCGGTCCTACGGAGATGTTCGGAGAG
TTGTCGATATTCGATCCGGAGCCCCGAAGGTCTGAGGCCCGAGCGCTGACCGCCGTGGCGGCAAGGGGCATGGATCGCGA
CACCATGCGCTGGTGGATTGCCCACCACAGCGACGCGGCCGAACAACTGCTCAGGGTGCTCGCCCGGCAGGTGAGGAAGG
CCACCCGCAAGTTGGCCGACATACCTCACGCCGATATCACCGCGCGAGTGGCCGCGCAGCTGCTCGACCTCGCCCAACGG
TTCGGGACCATAGAAGGCGACTCGGTGTACGTCGAACATGGCCTTTCGCAGCTCGAGCTCGCCGACCTGGTTGGGACATC
GCGAGAGTCCATGTGCCGTGTGCTGCACGAATTCGAGAAGCGCGGACTTATCCAGGTCCACGGCACTTCCCTGACGATCT
ACGACTGCGAGGTACTTTCCGTGCGCAACCATGCGGCAAGTGGAGTGATCGAGAAATGA

Upstream 100 bases:

>100_bases
GATCCCTATCTCAGTCATACCCCGTTTGCATACCCCGTTTGTCACTGCCAAGAACGGGTAGGCGGGCTCAGTACGACAGT
CCACGGAAGATGGAGCGATT

Downstream 100 bases:

>100_bases
ATACCGCACTGTCAGTGACTGATTCACAGATTCCGACATACCCGCGCCCGCTCTCCGCGGAGGAAGTCAGACAGATCGAC
GCCTACTGGCGCGCCGCGAA

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MHSAVEETPVFRGMSTPAVAAATARLTTEHFQPDEVIFRPGDPGDRMYLVTQGKVALSRRSGDGAERLATLVGPTEMFGE
LSIFDPEPRRSEARALTAVAARGMDRDTMRWWIAHHSDAAEQLLRVLARQVRKATRKLADIPHADITARVAAQLLDLAQR
FGTIEGDSVYVEHGLSQLELADLVGTSRESMCRVLHEFEKRGLIQVHGTSLTIYDCEVLSVRNHAASGVIEK

Sequences:

>Translated_232_residues
MHSAVEETPVFRGMSTPAVAAATARLTTEHFQPDEVIFRPGDPGDRMYLVTQGKVALSRRSGDGAERLATLVGPTEMFGE
LSIFDPEPRRSEARALTAVAARGMDRDTMRWWIAHHSDAAEQLLRVLARQVRKATRKLADIPHADITARVAAQLLDLAQR
FGTIEGDSVYVEHGLSQLELADLVGTSRESMCRVLHEFEKRGLIQVHGTSLTIYDCEVLSVRNHAASGVIEK
>Mature_232_residues
MHSAVEETPVFRGMSTPAVAAATARLTTEHFQPDEVIFRPGDPGDRMYLVTQGKVALSRRSGDGAERLATLVGPTEMFGE
LSIFDPEPRRSEARALTAVAARGMDRDTMRWWIAHHSDAAEQLLRVLARQVRKATRKLADIPHADITARVAAQLLDLAQR
FGTIEGDSVYVEHGLSQLELADLVGTSRESMCRVLHEFEKRGLIQVHGTSLTIYDCEVLSVRNHAASGVIEK

Specific function: Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=186, Percent_Identity=25.2688172043011, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25582; Mature: 25582

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSAVEETPVFRGMSTPAVAAATARLTTEHFQPDEVIFRPGDPGDRMYLVTQGKVALSRR
CCCCHHHCCHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCEEEECC
SGDGAERLATLVGPTEMFGELSIFDPEPRRSEARALTAVAARGMDRDTMRWWIAHHSDAA
CCCHHHHHHHHHCCHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHH
EQLLRVLARQVRKATRKLADIPHADITARVAAQLLDLAQRFGTIEGDSVYVEHGLSQLEL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHCCCCCHHHH
ADLVGTSRESMCRVLHEFEKRGLIQVHGTSLTIYDCEVLSVRNHAASGVIEK
HHHHCCCHHHHHHHHHHHHHCCEEEEECCEEEEEEEEEEEHHHHHCCCCCCC
>Mature Secondary Structure
MHSAVEETPVFRGMSTPAVAAATARLTTEHFQPDEVIFRPGDPGDRMYLVTQGKVALSRR
CCCCHHHCCHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCEEEECC
SGDGAERLATLVGPTEMFGELSIFDPEPRRSEARALTAVAARGMDRDTMRWWIAHHSDAA
CCCHHHHHHHHHCCHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHH
EQLLRVLARQVRKATRKLADIPHADITARVAAQLLDLAQRFGTIEGDSVYVEHGLSQLEL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHCCCCCHHHH
ADLVGTSRESMCRVLHEFEKRGLIQVHGTSLTIYDCEVLSVRNHAASGVIEK
HHHHCCCHHHHHHHHHHHHHCCEEEEECCEEEEEEEEEEEHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1630321 [H]