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The map label for this gene is yqjI [H]

Identifier: 169629499

GI number: 169629499

Start: 2473091

End: 2474545

Strand: Reverse

Name: yqjI [H]

Synonym: MAB_2413c

Alternate gene names: 169629499

Gene position: 2474545-2473091 (Counterclockwise)

Preceding gene: 169629500

Following gene: 169629498

Centisome position: 48.83

GC content: 65.91

Gene sequence:

>1455_bases
GTGACGGCTGCAGACGGCTCGGCGCAGGGTAAGGCTCAGATCGGCGTGACGGGACTTGCCGTCATGGGATCCAATATCGC
GCGCAACTTCGCGCGGCACGGATACACGGTCGCACTGCACAACCGGTCCATCGCCAAGACCGACGCGCTGCTCGCCGAGC
ACGGATCCGAGGGGAACTTCGTCCGCAGCGAGAGCATCGAAGAGTTCGTGGCGGCCCTGGAGCGGCCGCGCCGCGTGCTC
ATCATGGTCAAGGCCGGTGACCCGACCGACGCGGTGATCAACGAACTGGCCGATGCCATGGAGCAGGGCGACATCATCAT
CGACGGCGGCAACTCCCTGTACACCGACACCATCCGCCGCGAGAAGGCGATGGCCGACCGCGGCCTGCACTTCGTCGGTG
CCGGCATCTCCGGCGGCGAGGAAGGGGCGCTCAATGGCCCCTCGATCATGCCCGGAGGACCGAAGAAGTCCTATGAGTCC
CTCGGCCCGCTGCTGGAGGAGATCTCGGCGCACGTCGACGGTGTGCCCTGCTGCACCCACATCGGCCCCGATGGCTCCGG
CCACTTCGTGAAGATGGTGCACAACGGCATCGAATACTCGGACATGCAGCTCATCGGCGAGGCCTACCAGCTGCTGCGCG
ACGGCCTCGGCATGAGCGCACCGCAGATCGCCGATGTCTTCACCGCATGGAACAAGGGCGAGCTGGAAAGCTACCTCATC
GAGATCACCGCCGAGGTGCTCAAGCAGGTCGACGCCAAGACCGGCAAGCCACTCGTGGACGTCATCGTCGATGCCGCCGA
GCAGAAGGGCACCGGCCGCTGGACCGTCAAGTCCGCACTCGACCTGGGAGTGCCGGTCACCGGCATCGCGGAGGCCGTGT
TCGCCCGTGCGCTGTCCGGCTCGAAGCCGCAACGCGCCGCTTCCGTCGGCTTCGCCTCAGGTCAGCTCGGCGAAAAGCCA
AGCGATGCAAAACAGTTCGTTGAAGATGTGCGCCAAGCGCTGTACGCCTCCAAGATCGTGGCCTACGCCCAGGGGTTCAA
CCAGATCGCGGCGGGCAGCGCCGAGTACGGCTGGAACGTCAGCCCTGGCGATCTGGCCACCATTTGGCGTGGCGGCTGCA
TCATCCGCGCGCAGTTCCTCAATCGGGTCAAAGAAGCATTCGCCGATCGGCCGGACCTGGCCACGCTGATCGCGGCACCG
TACTTCCGCGACGCCGTCGAGAAGGGCATCGACAGCTGGCGGCGCGTGGTGGTCACCGCCACCCAGCTGGGTATTCCGGT
ACCAGGCTTCGCCTCGTCGCTGTCTTACTACGACGGTCTGCGTACCGATCGCCTGCCCGCCGCACTGACCCAGGCGCAAC
GCGACTTCTTCGGTGCCCACACCTATGAGCGCATCGACGCCCCCGGCAAGTTCCACACGCTCTGGAGCGGCGACCGCAAC
GAAGTAGAGGCGTAA

Upstream 100 bases:

>100_bases
CGAGAATCGGTGATGAGGCGCCCCTATGTGGGAGCGCTCCCCGGCTTGCGCGATGAGCGAACGGCTTTGGTGCGCAACAC
GTCAACGAAAGGATGTGCTG

Downstream 100 bases:

>100_bases
CGGCCAGAAGAGTAGGGCGTCACATATGAAGTTCCTGGACGGGCAGCGGCCGCCGTACGATCTCACGTATGACGACGTCT
TCGTGGTGCCCAACCACTCC

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTAADGSAQGKAQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDALLAEHGSEGNFVRSESIEEFVAALERPRRVL
IMVKAGDPTDAVINELADAMEQGDIIIDGGNSLYTDTIRREKAMADRGLHFVGAGISGGEEGALNGPSIMPGGPKKSYES
LGPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLLRDGLGMSAPQIADVFTAWNKGELESYLI
EITAEVLKQVDAKTGKPLVDVIVDAAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSKPQRAASVGFASGQLGEKP
SDAKQFVEDVRQALYASKIVAYAQGFNQIAAGSAEYGWNVSPGDLATIWRGGCIIRAQFLNRVKEAFADRPDLATLIAAP
YFRDAVEKGIDSWRRVVVTATQLGIPVPGFASSLSYYDGLRTDRLPAALTQAQRDFFGAHTYERIDAPGKFHTLWSGDRN
EVEA

Sequences:

>Translated_484_residues
MTAADGSAQGKAQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDALLAEHGSEGNFVRSESIEEFVAALERPRRVL
IMVKAGDPTDAVINELADAMEQGDIIIDGGNSLYTDTIRREKAMADRGLHFVGAGISGGEEGALNGPSIMPGGPKKSYES
LGPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLLRDGLGMSAPQIADVFTAWNKGELESYLI
EITAEVLKQVDAKTGKPLVDVIVDAAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSKPQRAASVGFASGQLGEKP
SDAKQFVEDVRQALYASKIVAYAQGFNQIAAGSAEYGWNVSPGDLATIWRGGCIIRAQFLNRVKEAFADRPDLATLIAAP
YFRDAVEKGIDSWRRVVVTATQLGIPVPGFASSLSYYDGLRTDRLPAALTQAQRDFFGAHTYERIDAPGKFHTLWSGDRN
EVEA
>Mature_483_residues
TAADGSAQGKAQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDALLAEHGSEGNFVRSESIEEFVAALERPRRVLI
MVKAGDPTDAVINELADAMEQGDIIIDGGNSLYTDTIRREKAMADRGLHFVGAGISGGEEGALNGPSIMPGGPKKSYESL
GPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLLRDGLGMSAPQIADVFTAWNKGELESYLIE
ITAEVLKQVDAKTGKPLVDVIVDAAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSKPQRAASVGFASGQLGEKPS
DAKQFVEDVRQALYASKIVAYAQGFNQIAAGSAEYGWNVSPGDLATIWRGGCIIRAQFLNRVKEAFADRPDLATLIAAPY
FRDAVEKGIDSWRRVVVTATQLGIPVPGFASSLSYYDGLRTDRLPAALTQAQRDFFGAHTYERIDAPGKFHTLWSGDRNE
VEA

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=470, Percent_Identity=51.2765957446809, Blast_Score=464, Evalue=1e-131,
Organism=Escherichia coli, GI1788341, Length=466, Percent_Identity=53.4334763948498, Blast_Score=515, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17542558, Length=471, Percent_Identity=50.1061571125265, Blast_Score=477, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6321695, Length=451, Percent_Identity=49.2239467849224, Blast_Score=459, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6321977, Length=478, Percent_Identity=49.163179916318, Blast_Score=458, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24639279, Length=477, Percent_Identity=48.0083857442348, Blast_Score=442, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 51665; Mature: 51534

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAADGSAQGKAQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDALLAEHGSEGNF
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCE
VRSESIEEFVAALERPRRVLIMVKAGDPTDAVINELADAMEQGDIIIDGGNSLYTDTIRR
EHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHH
EKAMADRGLHFVGAGISGGEEGALNGPSIMPGGPKKSYESLGPLLEEISAHVDGVPCCTH
HHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECC
IGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLLRDGLGMSAPQIADVFTAWNKGELESYLI
CCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHH
EITAEVLKQVDAKTGKPLVDVIVDAAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSG
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHCC
SKPQRAASVGFASGQLGEKPSDAKQFVEDVRQALYASKIVAYAQGFNQIAAGSAEYGWNV
CCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCC
SPGDLATIWRGGCIIRAQFLNRVKEAFADRPDLATLIAAPYFRDAVEKGIDSWRRVVVTA
CCCCHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLGIPVPGFASSLSYYDGLRTDRLPAALTQAQRDFFGAHTYERIDAPGKFHTLWSGDRN
HHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCC
EVEA
CCCC
>Mature Secondary Structure 
TAADGSAQGKAQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDALLAEHGSEGNF
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCE
VRSESIEEFVAALERPRRVLIMVKAGDPTDAVINELADAMEQGDIIIDGGNSLYTDTIRR
EHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHH
EKAMADRGLHFVGAGISGGEEGALNGPSIMPGGPKKSYESLGPLLEEISAHVDGVPCCTH
HHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECC
IGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLLRDGLGMSAPQIADVFTAWNKGELESYLI
CCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHH
EITAEVLKQVDAKTGKPLVDVIVDAAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSG
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHCC
SKPQRAASVGFASGQLGEKPSDAKQFVEDVRQALYASKIVAYAQGFNQIAAGSAEYGWNV
CCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCC
SPGDLATIWRGGCIIRAQFLNRVKEAFADRPDLATLIAAPYFRDAVEKGIDSWRRVVVTA
CCCCHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLGIPVPGFASSLSYYDGLRTDRLPAALTQAQRDFFGAHTYERIDAPGKFHTLWSGDRN
HHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCC
EVEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]