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The map label for this gene is ppe1 [H]

Identifier: 169629340

GI number: 169629340

Start: 2283437

End: 2284948

Strand: Reverse

Name: ppe1 [H]

Synonym: MAB_2254c

Alternate gene names: 169629340

Gene position: 2284948-2283437 (Counterclockwise)

Preceding gene: 169629347

Following gene: 169629333

Centisome position: 45.09

GC content: 63.56

Gene sequence:

>1512_bases
ATGTCGGCCCCAATCTGGATGGCATTTCCCCCCGAGGTGCATTCGGCGCTACTCGGCGCGGGACCTGGTCCGGGTCCACT
GCTGGCGGCGGCGGCGCAATGGCACGCGCTGTCGTATGAATACTCAATGGCCGCAACAGAACTGACTCAACTACTGGGAG
TGACAGCGGCAGGAGTATGGCAAGGATCCAGCGCCACGCAGTACGTGGCCAGTCACACGCCGTACCTGGCCTGGCTTACT
CAACAGAGCGCAACGAGTGCCGCCAACGCTGCACTGCACGAGACCAGCGCAGCTGCCTACACCACGGCCCTGGCAGCGAT
GCCGACATTGCCCGAGTTGGCGACGAACCATACTGTTCATGGCATCTTGGTGGGCACCAACTTCTTTGGGATCAATACGA
TCCCAATTGCCCTCAACGAAGCCGACTATGTTCGAATGTGGGTGCAGGCCGCTACCACGATGGGTGTCTACCAAGGAGTT
TCGAGCACCGCGGTGGCCGCAGCCGCGCCCACCACCACCTCTCCATTAATCATGCCCCCTGGCAGCGAGTTGAGCCGGAT
GGCCGCCGATATGTCCGGATTCGCCGCACAGGCGCAGGCCACCGAATCCGGCTCGGCGCTGGACAGCAGCAACAGTGTTA
TTGATCAGCTGTTGAATTTCTTCCGCGACCCGCTGGGCACACTGCGCCAGATCATCGAGGATTTCATCCGAAATCCTGGG
GCCGCGCTAGCCACCTGGCTGCCTTTCCTGCTGGTACTCGCATCGATGACGTATGTGCTTTTTGCGCAGGTGTTTTGGCT
GTTCTGGGCAGCGTTGCTTTCGGCGCCTCTCTGGTTGCCACTACTGATCTTGGCGGCCTGGCAGTATCTACAACCCCCCG
CCGTCGACGCGGCTCCGGCCGACGAAATTCGGCCCGAGCTAGGCAGCACCGTCAATGGCCAGCGAGAGCACATAGAGCCC
CTCCCTGCAATCGCATTGGCTCCCACGGCCACACCGGTACCGACCGCAAGTGCGTCGGCCCCCTCGGCCCCGGCACCGGC
CCCCGCACCGACTGCCGCTGGCGCCGGGTTTGCGCCATATCTCGTAGGGGCGATACCCGACGAACCACCCGCCATCCAGT
TCGGACCGACGCTCAATGAGGGCAACAAGGCCCAGGCGCCGGCCTCCGGGATCTCTGCCGCGGCAGCGGCGGCAGCGTCT
GCCCGCTCGCGGGCACGACGTAAACGTGGTGCACGGGTGAAAGACCCAGCCCCGCAATACATGGACATGAACGTGACAGT
CGATGCCGACTACGGTGAGCCGCCCGGATCGGCACAGCGCCAAAGCACCGCCTCGGCTCGTGGTGCCGGACATCTCGGAT
TGGCCGGCACCAGTCCAAAGACCACGGCTACCGCTGCAGGTCTTGTCGCGCGCGGCAGTGCCGGCAGCGACACCGATGTG
CCGGAAACCGCCCGGATCGTGCCCATGATCCCCACCACGTGGAGTACAGATTCTGATGAAGCTATCGACTGA

Upstream 100 bases:

>100_bases
GCCTTGAAATCACCGAAAGGCTGTGGGTTGAGTAGTCAGGAACGGGCGGTTCGGCCCGAATACGGCACGACCGAGCACGT
GAGCTTGCGGGGCTAGCTGG

Downstream 100 bases:

>100_bases
GCCGGGGTTAACCGACGGCTAGCTTGCATGTCACGACCATCGGTCAGACAGTTGCCACCAGGAACTCCTCGGCAGAGAGT
CCGGCGGCGGGCACATAGCG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MSAPIWMAFPPEVHSALLGAGPGPGPLLAAAAQWHALSYEYSMAATELTQLLGVTAAGVWQGSSATQYVASHTPYLAWLT
QQSATSAANAALHETSAAAYTTALAAMPTLPELATNHTVHGILVGTNFFGINTIPIALNEADYVRMWVQAATTMGVYQGV
SSTAVAAAAPTTTSPLIMPPGSELSRMAADMSGFAAQAQATESGSALDSSNSVIDQLLNFFRDPLGTLRQIIEDFIRNPG
AALATWLPFLLVLASMTYVLFAQVFWLFWAALLSAPLWLPLLILAAWQYLQPPAVDAAPADEIRPELGSTVNGQREHIEP
LPAIALAPTATPVPTASASAPSAPAPAPAPTAAGAGFAPYLVGAIPDEPPAIQFGPTLNEGNKAQAPASGISAAAAAAAS
ARSRARRKRGARVKDPAPQYMDMNVTVDADYGEPPGSAQRQSTASARGAGHLGLAGTSPKTTATAAGLVARGSAGSDTDV
PETARIVPMIPTTWSTDSDEAID

Sequences:

>Translated_503_residues
MSAPIWMAFPPEVHSALLGAGPGPGPLLAAAAQWHALSYEYSMAATELTQLLGVTAAGVWQGSSATQYVASHTPYLAWLT
QQSATSAANAALHETSAAAYTTALAAMPTLPELATNHTVHGILVGTNFFGINTIPIALNEADYVRMWVQAATTMGVYQGV
SSTAVAAAAPTTTSPLIMPPGSELSRMAADMSGFAAQAQATESGSALDSSNSVIDQLLNFFRDPLGTLRQIIEDFIRNPG
AALATWLPFLLVLASMTYVLFAQVFWLFWAALLSAPLWLPLLILAAWQYLQPPAVDAAPADEIRPELGSTVNGQREHIEP
LPAIALAPTATPVPTASASAPSAPAPAPAPTAAGAGFAPYLVGAIPDEPPAIQFGPTLNEGNKAQAPASGISAAAAAAAS
ARSRARRKRGARVKDPAPQYMDMNVTVDADYGEPPGSAQRQSTASARGAGHLGLAGTSPKTTATAAGLVARGSAGSDTDV
PETARIVPMIPTTWSTDSDEAID
>Mature_502_residues
SAPIWMAFPPEVHSALLGAGPGPGPLLAAAAQWHALSYEYSMAATELTQLLGVTAAGVWQGSSATQYVASHTPYLAWLTQ
QSATSAANAALHETSAAAYTTALAAMPTLPELATNHTVHGILVGTNFFGINTIPIALNEADYVRMWVQAATTMGVYQGVS
STAVAAAAPTTTSPLIMPPGSELSRMAADMSGFAAQAQATESGSALDSSNSVIDQLLNFFRDPLGTLRQIIEDFIRNPGA
ALATWLPFLLVLASMTYVLFAQVFWLFWAALLSAPLWLPLLILAAWQYLQPPAVDAAPADEIRPELGSTVNGQREHIEPL
PAIALAPTATPVPTASASAPSAPAPAPAPTAAGAGFAPYLVGAIPDEPPAIQFGPTLNEGNKAQAPASGISAAAAAAASA
RSRARRKRGARVKDPAPQYMDMNVTVDADYGEPPGSAQRQSTASARGAGHLGLAGTSPKTTATAAGLVARGSAGSDTDVP
ETARIVPMIPTTWSTDSDEAID

Specific function: Unknown

COG id: COG5651

COG function: function code N; PPE-repeat proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000030 [H]

Pfam domain/function: PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 51765; Mature: 51634

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPIWMAFPPEVHSALLGAGPGPGPLLAAAAQWHALSYEYSMAATELTQLLGVTAAGVW
CCCCEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGSSATQYVASHTPYLAWLTQQSATSAANAALHETSAAAYTTALAAMPTLPELATNHTVH
CCCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEE
GILVGTNFFGINTIPIALNEADYVRMWVQAATTMGVYQGVSSTAVAAAAPTTTSPLIMPP
EEEEECCEECCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCEEECC
GSELSRMAADMSGFAAQAQATESGSALDSSNSVIDQLLNFFRDPLGTLRQIIEDFIRNPG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
AALATWLPFLLVLASMTYVLFAQVFWLFWAALLSAPLWLPLLILAAWQYLQPPAVDAAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCH
DEIRPELGSTVNGQREHIEPLPAIALAPTATPVPTASASAPSAPAPAPAPTAAGAGFAPY
HHHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LVGAIPDEPPAIQFGPTLNEGNKAQAPASGISAAAAAAASARSRARRKRGARVKDPAPQY
HHCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
MDMNVTVDADYGEPPGSAQRQSTASARGAGHLGLAGTSPKTTATAAGLVARGSAGSDTDV
EEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
PETARIVPMIPTTWSTDSDEAID
CCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPIWMAFPPEVHSALLGAGPGPGPLLAAAAQWHALSYEYSMAATELTQLLGVTAAGVW
CCCEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGSSATQYVASHTPYLAWLTQQSATSAANAALHETSAAAYTTALAAMPTLPELATNHTVH
CCCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEE
GILVGTNFFGINTIPIALNEADYVRMWVQAATTMGVYQGVSSTAVAAAAPTTTSPLIMPP
EEEEECCEECCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCEEECC
GSELSRMAADMSGFAAQAQATESGSALDSSNSVIDQLLNFFRDPLGTLRQIIEDFIRNPG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
AALATWLPFLLVLASMTYVLFAQVFWLFWAALLSAPLWLPLLILAAWQYLQPPAVDAAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCH
DEIRPELGSTVNGQREHIEPLPAIALAPTATPVPTASASAPSAPAPAPAPTAAGAGFAPY
HHHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LVGAIPDEPPAIQFGPTLNEGNKAQAPASGISAAAAAAASARSRARRKRGARVKDPAPQY
HHCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
MDMNVTVDADYGEPPGSAQRQSTASARGAGHLGLAGTSPKTTATAAGLVARGSAGSDTDV
EEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
PETARIVPMIPTTWSTDSDEAID
CCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]