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The map label for this gene is fabG [C]

Identifier: 169629280

GI number: 169629280

Start: 2208992

End: 2209783

Strand: Direct

Name: fabG [C]

Synonym: MAB_2194

Alternate gene names: 169629280

Gene position: 2208992-2209783 (Clockwise)

Preceding gene: 169629278

Following gene: 169629281

Centisome position: 43.59

GC content: 66.54

Gene sequence:

>792_bases
GTGACCGACACGGTGCGACACTCCGGCCAGCTGGGGGATAAGCCGCTTGGGCGAAGACCGTCAACGGTGGTGATCTTTGG
GGGCCGTAGCGAGATCGGACTCGAGGTGGCGACCCGATTGGCGCCGGATAACACGGTGGTGTTGGCCGCGCGCCGGGCAG
ATGACCTGCGCGAAGAGAAGCGGCGCATACTCGAGGCAGGCGCTACCGGTATCGACTGCGTTGAGTTTGACGCGGGCCGG
CTTGACACCCATGAGTCGGTATTGGATTCCATCATCGAGCGGTACGGGGCCATCGACGTAGCAGTCCTTGCGTTCGGACT
GTTGGGTGACCAGGCGCGGGCCGAGACCGATTCCGAACATGCCGCCGCGATAGTGCACATCGACTATGTGGCTCAGATCG
CGCTGCTGACCAGCCTGGCTGTGCGCATGCGCGGCGTCGGCCGCGGTGCCCTGGTGGTCTTTTCATCGATCGCCGGCTGG
CGCGTGCGCCGGGCCAATTACGTGTACGGATCGGCCAAGGCGGGACTGGACGGTTTCGCGAGCGGACTTGCCGACGCGCT
CCATGGATCCGGAGTCCGCCTGCTGATAGCGCGGCCGGGTTTCGTGATCGGCCGAATGTCGGCGGGTATGTCACCGGCGC
CTTTGTCGAGCACGCCGCCCCAAGTGGCCGCAGCGACGGTGCGGGCGTTGCGCGGCGGAAAGCGCACGGTGTGGATACCC
CGGCCGCTGGGTGCGCTCGCCTTCGTCATGCGGTGGGTACCGTCGTCGGTATGGCGCAGGATGCCGCGATGA

Upstream 100 bases:

>100_bases
AGATGGCGCTCGGACAGGAACGCCAGCGCATCATCGGTAAGTCGGGTTGTAGGGGTGTTCGGCATCAACCATCACGCTAG
CGCAGGACATAATCGCTGAC

Downstream 100 bases:

>100_bases
GCCCGTCGGGCGAAGAGCATGGAGCACCGATGAGCCCGTCGGGCCACGAGCCTGAAGCACCGACGGGCCGGATCACCGTG
GTCGGGATAGGCGCCGACGG

Product: Probabme short-chain dehydrogenase/reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTDTVRHSGQLGDKPLGRRPSTVVIFGGRSEIGLEVATRLAPDNTVVLAARRADDLREEKRRILEAGATGIDCVEFDAGR
LDTHESVLDSIIERYGAIDVAVLAFGLLGDQARAETDSEHAAAIVHIDYVAQIALLTSLAVRMRGVGRGALVVFSSIAGW
RVRRANYVYGSAKAGLDGFASGLADALHGSGVRLLIARPGFVIGRMSAGMSPAPLSSTPPQVAAATVRALRGGKRTVWIP
RPLGALAFVMRWVPSSVWRRMPR

Sequences:

>Translated_263_residues
MTDTVRHSGQLGDKPLGRRPSTVVIFGGRSEIGLEVATRLAPDNTVVLAARRADDLREEKRRILEAGATGIDCVEFDAGR
LDTHESVLDSIIERYGAIDVAVLAFGLLGDQARAETDSEHAAAIVHIDYVAQIALLTSLAVRMRGVGRGALVVFSSIAGW
RVRRANYVYGSAKAGLDGFASGLADALHGSGVRLLIARPGFVIGRMSAGMSPAPLSSTPPQVAAATVRALRGGKRTVWIP
RPLGALAFVMRWVPSSVWRRMPR
>Mature_262_residues
TDTVRHSGQLGDKPLGRRPSTVVIFGGRSEIGLEVATRLAPDNTVVLAARRADDLREEKRRILEAGATGIDCVEFDAGRL
DTHESVLDSIIERYGAIDVAVLAFGLLGDQARAETDSEHAAAIVHIDYVAQIALLTSLAVRMRGVGRGALVVFSSIAGWR
VRRANYVYGSAKAGLDGFASGLADALHGSGVRLLIARPGFVIGRMSAGMSPAPLSSTPPQVAAATVRALRGGKRTVWIPR
PLGALAFVMRWVPSSVWRRMPR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 28072; Mature: 27941

Theoretical pI: Translated: 11.02; Mature: 11.02

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTVRHSGQLGDKPLGRRPSTVVIFGGRSEIGLEVATRLAPDNTVVLAARRADDLREEK
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHH
RRILEAGATGIDCVEFDAGRLDTHESVLDSIIERYGAIDVAVLAFGLLGDQARAETDSEH
HHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHCCCCCCC
AAAIVHIDYVAQIALLTSLAVRMRGVGRGALVVFSSIAGWRVRRANYVYGSAKAGLDGFA
CEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECEEEECCCCCCHHHHH
SGLADALHGSGVRLLIARPGFVIGRMSAGMSPAPLSSTPPQVAAATVRALRGGKRTVWIP
HHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEC
RPLGALAFVMRWVPSSVWRRMPR
CCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDTVRHSGQLGDKPLGRRPSTVVIFGGRSEIGLEVATRLAPDNTVVLAARRADDLREEK
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHH
RRILEAGATGIDCVEFDAGRLDTHESVLDSIIERYGAIDVAVLAFGLLGDQARAETDSEH
HHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHCCCCCCC
AAAIVHIDYVAQIALLTSLAVRMRGVGRGALVVFSSIAGWRVRRANYVYGSAKAGLDGFA
CEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECEEEECCCCCCHHHHH
SGLADALHGSGVRLLIARPGFVIGRMSAGMSPAPLSSTPPQVAAATVRALRGGKRTVWIP
HHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEC
RPLGALAFVMRWVPSSVWRRMPR
CCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]