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The map label for this gene is desA1 [H]

Identifier: 169629243

GI number: 169629243

Start: 2171182

End: 2172102

Strand: Direct

Name: desA1 [H]

Synonym: MAB_2157

Alternate gene names: 169629243

Gene position: 2171182-2172102 (Clockwise)

Preceding gene: 169629242

Following gene: 169629245

Centisome position: 42.85

GC content: 62.76

Gene sequence:

>921_bases
ATGGTGACTGGACTGCAAACGCGACTACTCACCGAACTGGAGCCCGTTGTCGAGGAAAACCTCGAACGGCATTTGCGTGC
CGTAAGGCCTTGGGCCCCACACGATTACGTGCCCTGGAGCCGGGGCAGGGACTTCGCCTTCCTTGGGGGTGAGGATTGGA
AACCGGAGGACAGCCCCCTGGATCCGGTCGCCCAGGCGGCCCTGGTGGTCAACCTGCTCACCGAGGACAACCTGCCGTCG
TATCACCGAGAGATCGCCACACGGTTCGGACGTGACGGTGCCTGGGGGACATGGGTGGGCCAATGGACCGCCGAAGAAGG
GCGGCACAGCATCGCGCTTCGCGACTACCTGGTGGTGACCCGCGGTGTCGATCCGGGCAATTTGGAAGCGATGCGCATGG
CGCATACCGTGGCCGGCTACGACTCGGGCGACAAAACGCCGCTGGAGGCATTGGCGTATGTGTCATTCCAGGAGCTGGCC
ACACGGATATCCCATCGCAACACGGGCAAGGCATCGGGCTGCCCGATTGCCGATCAGCTGCTGGCCCGGGTCGCGCTGGA
CGAAAACCTACACATGGTGTTCTACCGCAACCTCATGCTGGCGGCTCTCGATATCGAGCCCGACGCGGCTATGCAGGCCA
TCTGCAAGGAGATCGTCGGTTTCGCGATGCCCGGCATGGGCATGGAAGGTTTCGCGCAGAACGCCATAGCCATCGCCAAG
GCGGGAATCTATGACCTGCGCATCCATCACGATGACGTGCTACAGCCCATCCTGCGTTTCTGGCGCGTGTTCGAACGTGC
CGACATCGGACCCGAGGGTGAGCAGGCGCGGGATACCTTAGCGAAATTCCTTGCCGCCGTGGATGAACGCGCAAAGTACT
ACGAAGAGAAGGCGGCATCACGCGCCGCGGCGCAGGTGTAG

Upstream 100 bases:

>100_bases
CTTAGTCCTCACAAGTTCACCCATCTCTAACCTACTTGAGCGTAACTTACGGTACCGTAGGTTACGGATCGTGATCAGGT
CGTACAGAGAGGTGGACGAG

Downstream 100 bases:

>100_bases
GTGGCTTGTCGGGCTACCGGGAGCCGCTATTTCCCGCCTTGCGGGTGGGGCGCTGCTGACCGCGGCCGCCGCCACGCCGC
GGCGTACGTGCCGGACGGCC

Product: acyl-[acyl-carrier protein] desaturase

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA1 [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MVTGLQTRLLTELEPVVEENLERHLRAVRPWAPHDYVPWSRGRDFAFLGGEDWKPEDSPLDPVAQAALVVNLLTEDNLPS
YHREIATRFGRDGAWGTWVGQWTAEEGRHSIALRDYLVVTRGVDPGNLEAMRMAHTVAGYDSGDKTPLEALAYVSFQELA
TRISHRNTGKASGCPIADQLLARVALDENLHMVFYRNLMLAALDIEPDAAMQAICKEIVGFAMPGMGMEGFAQNAIAIAK
AGIYDLRIHHDDVLQPILRFWRVFERADIGPEGEQARDTLAKFLAAVDERAKYYEEKAASRAAAQV

Sequences:

>Translated_306_residues
MVTGLQTRLLTELEPVVEENLERHLRAVRPWAPHDYVPWSRGRDFAFLGGEDWKPEDSPLDPVAQAALVVNLLTEDNLPS
YHREIATRFGRDGAWGTWVGQWTAEEGRHSIALRDYLVVTRGVDPGNLEAMRMAHTVAGYDSGDKTPLEALAYVSFQELA
TRISHRNTGKASGCPIADQLLARVALDENLHMVFYRNLMLAALDIEPDAAMQAICKEIVGFAMPGMGMEGFAQNAIAIAK
AGIYDLRIHHDDVLQPILRFWRVFERADIGPEGEQARDTLAKFLAAVDERAKYYEEKAASRAAAQV
>Mature_306_residues
MVTGLQTRLLTELEPVVEENLERHLRAVRPWAPHDYVPWSRGRDFAFLGGEDWKPEDSPLDPVAQAALVVNLLTEDNLPS
YHREIATRFGRDGAWGTWVGQWTAEEGRHSIALRDYLVVTRGVDPGNLEAMRMAHTVAGYDSGDKTPLEALAYVSFQELA
TRISHRNTGKASGCPIADQLLARVALDENLHMVFYRNLMLAALDIEPDAAMQAICKEIVGFAMPGMGMEGFAQNAIAIAK
AGIYDLRIHHDDVLQPILRFWRVFERADIGPEGEQARDTLAKFLAAVDERAKYYEEKAASRAAAQV

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 34110; Mature: 34110

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTGLQTRLLTELEPVVEENLERHLRAVRPWAPHDYVPWSRGRDFAFLGGEDWKPEDSPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
DPVAQAALVVNLLTEDNLPSYHREIATRFGRDGAWGTWVGQWTAEEGRHSIALRDYLVVT
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHCCCCHHCCCCEEHHHHEEEEE
RGVDPGNLEAMRMAHTVAGYDSGDKTPLEALAYVSFQELATRISHRNTGKASGCPIADQL
CCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
LARVALDENLHMVFYRNLMLAALDIEPDAAMQAICKEIVGFAMPGMGMEGFAQNAIAIAK
HHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AGIYDLRIHHDDVLQPILRFWRVFERADIGPEGEQARDTLAKFLAAVDERAKYYEEKAAS
CCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAAQV
HHHCCC
>Mature Secondary Structure
MVTGLQTRLLTELEPVVEENLERHLRAVRPWAPHDYVPWSRGRDFAFLGGEDWKPEDSPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
DPVAQAALVVNLLTEDNLPSYHREIATRFGRDGAWGTWVGQWTAEEGRHSIALRDYLVVT
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHCCCCHHCCCCEEHHHHEEEEE
RGVDPGNLEAMRMAHTVAGYDSGDKTPLEALAYVSFQELATRISHRNTGKASGCPIADQL
CCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
LARVALDENLHMVFYRNLMLAALDIEPDAAMQAICKEIVGFAMPGMGMEGFAQNAIAIAK
HHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AGIYDLRIHHDDVLQPILRFWRVFERADIGPEGEQARDTLAKFLAAVDERAKYYEEKAAS
CCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAAQV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]