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The map label for this gene is mmgC [H]

Identifier: 169629167

GI number: 169629167

Start: 2081643

End: 2082788

Strand: Direct

Name: mmgC [H]

Synonym: MAB_2081

Alternate gene names: 169629167

Gene position: 2081643-2082788 (Clockwise)

Preceding gene: 169629166

Following gene: 169629168

Centisome position: 41.08

GC content: 59.51

Gene sequence:

>1146_bases
ATGTCCTCACCAATCTCTCCCTGGATGAATGCCGAATTACTCGAGCTTCGTGACCTCGCTGCGAAGTTCTTCTCGGCCGA
ATTGGCGCCGCATGCGAACCGCTTTGCAGACCAGCACCACGTCGACCGAGAACTGTGGAACCGAGCAGGCGAGCTTGGCC
TGCTCTGCATGTCTATACCTGAGGAATACGGCGGAGGCGGTGGCACTTTCGCGCACGAAGCGGTCGTGCTCGAAGAGCAG
GCCCGCATAGGTGACAGCTCATGGGGCGCGGGACTGCACAGCGGAATCGTCGCCCACTACATCCTGCAGTACGCGACTGA
AGAGCTGCGCGCGCAGTGGCTTCCCAAGATGGCGTCCGGTGAAATGATCGGGGCGATCGCCATGACAGAACCGGGGACCG
GGTCCGATCTGCAGAGCGTCAAGACGAAAGCCCTCCTGGACGGTGACGAGTACGTGATCACCGGCTCCAAGACTTTCATC
ACCAACGGCCAACAGGCCGACCTCATCATCGTTGTTGCCAAGACAGATCCGAGCCAGGGCGCTGCGGGCATCTCTTTGAT
CGTTGTCGAGGCTGACCGGGCGGGATTCCGGCGCGGCAAGGTTCTCGACAAAATCGGCCAGCGCGGCCAGGACACCTCCG
AGTTGTTCTTCGATGAAGTGAGAGTTCCGCGCTCGCATCTACTGGGCCAGGCTGAGGGACAGGGCTTCATTCAGCTGATG
ACGCAGCTGCCACAAGAGCGACTCATCGTAGCGGTGGGGGCTGTCGCAGCGATGGAACTTGCCCTGGAGCAGACGCTCAA
GTATACCCGTGAGCGGGAGGCGTTTGGTCGGCCTGTCTTTGGCTTTCAGAACACCAAGTTCACGCTGGCTGAAGCCGCGA
CCGAAACGCGCATCGCACGAGTGTTCCTCGACTACTGCATCGACCTGCACCTTGCGGGTCAACTCGACGTGCAGACCGTC
GCCATGGCGAAGTGGTGGACCACTGAGCGAGCGATGAAGGTACTCGATGACTGTATGCAGCTTCACGGCGGATATGGCTA
CATGACCGAGTACCCCATCTCGAGATTATGGGTGGATCAGCGCGTGCAAAAAATCTATGCCGGCACGAACGAGGTGATGA
AGGAAATCATCTCGCGTTCCCTATGA

Upstream 100 bases:

>100_bases
AAAAGGCCATCCGTGCCCGCCACTCTGCCGGCGAATACCTCATCGAAATCGAAACGTCATAACGTCGAATCCCAGGAATT
CCAACAGTCGGAAGGTAATC

Downstream 100 bases:

>100_bases
CTCAGATGAGTTGCCGCCTGCACGTTAGTCACCTGGAGGAGGATTGATGGCATCGATGGTGGTGCCGTATCGCCACGACA
TGGGCGGCCATTGCGGATCG

Product: acyl CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSSPISPWMNAELLELRDLAAKFFSAELAPHANRFADQHHVDRELWNRAGELGLLCMSIPEEYGGGGGTFAHEAVVLEEQ
ARIGDSSWGAGLHSGIVAHYILQYATEELRAQWLPKMASGEMIGAIAMTEPGTGSDLQSVKTKALLDGDEYVITGSKTFI
TNGQQADLIIVVAKTDPSQGAAGISLIVVEADRAGFRRGKVLDKIGQRGQDTSELFFDEVRVPRSHLLGQAEGQGFIQLM
TQLPQERLIVAVGAVAAMELALEQTLKYTREREAFGRPVFGFQNTKFTLAEAATETRIARVFLDYCIDLHLAGQLDVQTV
AMAKWWTTERAMKVLDDCMQLHGGYGYMTEYPISRLWVDQRVQKIYAGTNEVMKEIISRSL

Sequences:

>Translated_381_residues
MSSPISPWMNAELLELRDLAAKFFSAELAPHANRFADQHHVDRELWNRAGELGLLCMSIPEEYGGGGGTFAHEAVVLEEQ
ARIGDSSWGAGLHSGIVAHYILQYATEELRAQWLPKMASGEMIGAIAMTEPGTGSDLQSVKTKALLDGDEYVITGSKTFI
TNGQQADLIIVVAKTDPSQGAAGISLIVVEADRAGFRRGKVLDKIGQRGQDTSELFFDEVRVPRSHLLGQAEGQGFIQLM
TQLPQERLIVAVGAVAAMELALEQTLKYTREREAFGRPVFGFQNTKFTLAEAATETRIARVFLDYCIDLHLAGQLDVQTV
AMAKWWTTERAMKVLDDCMQLHGGYGYMTEYPISRLWVDQRVQKIYAGTNEVMKEIISRSL
>Mature_380_residues
SSPISPWMNAELLELRDLAAKFFSAELAPHANRFADQHHVDRELWNRAGELGLLCMSIPEEYGGGGGTFAHEAVVLEEQA
RIGDSSWGAGLHSGIVAHYILQYATEELRAQWLPKMASGEMIGAIAMTEPGTGSDLQSVKTKALLDGDEYVITGSKTFIT
NGQQADLIIVVAKTDPSQGAAGISLIVVEADRAGFRRGKVLDKIGQRGQDTSELFFDEVRVPRSHLLGQAEGQGFIQLMT
QLPQERLIVAVGAVAAMELALEQTLKYTREREAFGRPVFGFQNTKFTLAEAATETRIARVFLDYCIDLHLAGQLDVQTVA
MAKWWTTERAMKVLDDCMQLHGGYGYMTEYPISRLWVDQRVQKIYAGTNEVMKEIISRSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=369, Percent_Identity=47.6964769647696, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI226958412, Length=386, Percent_Identity=35.2331606217617, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=35.9649122807018, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=33.9622641509434, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI4501859, Length=381, Percent_Identity=28.8713910761155, Blast_Score=198, Evalue=8e-51,
Organism=Homo sapiens, GI7656849, Length=384, Percent_Identity=31.5104166666667, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI187960098, Length=370, Percent_Identity=32.4324324324324, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI4557231, Length=370, Percent_Identity=32.4324324324324, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI21361497, Length=374, Percent_Identity=32.3529411764706, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4557235, Length=392, Percent_Identity=31.3775510204082, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI76496475, Length=392, Percent_Identity=31.3775510204082, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI4503943, Length=402, Percent_Identity=28.1094527363184, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI7669494, Length=373, Percent_Identity=28.9544235924933, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI211971008, Length=290, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI48976061, Length=290, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38505218, Length=284, Percent_Identity=25, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=29.973474801061, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1786223, Length=347, Percent_Identity=27.6657060518732, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082384, Length=271, Percent_Identity=27.3062730627306, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081702, Length=348, Percent_Identity=25.8620689655172, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=36.7021276595745, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=32.8, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=33.3333333333333, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17508101, Length=359, Percent_Identity=31.1977715877437, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17570075, Length=390, Percent_Identity=32.0512820512821, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=32.7272727272727, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17551932, Length=334, Percent_Identity=34.1317365269461, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17533517, Length=370, Percent_Identity=32.1621621621622, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17505929, Length=334, Percent_Identity=33.2335329341317, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=286, Percent_Identity=35.3146853146853, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=31.830985915493, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=226, Percent_Identity=35.3982300884956, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=27.8985507246377, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=28.2258064516129, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI71985192, Length=287, Percent_Identity=31.7073170731707, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=24.7933884297521, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=295, Percent_Identity=26.4406779661017, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355753, Length=372, Percent_Identity=36.2903225806452, Blast_Score=227, Evalue=8e-60,
Organism=Drosophila melanogaster, GI24666513, Length=368, Percent_Identity=31.25, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21356377, Length=361, Percent_Identity=32.1329639889197, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=34.4919786096257, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=32.3529411764706, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI281363737, Length=403, Percent_Identity=29.5285359801489, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI19920834, Length=380, Percent_Identity=28.9473684210526, Blast_Score=138, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42085; Mature: 41953

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPISPWMNAELLELRDLAAKFFSAELAPHANRFADQHHVDRELWNRAGELGLLCMSIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
EEYGGGGGTFAHEAVVLEEQARIGDSSWGAGLHSGIVAHYILQYATEELRAQWLPKMASG
HHHCCCCCCHHHHHHEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EMIGAIAMTEPGTGSDLQSVKTKALLDGDEYVITGSKTFITNGQQADLIIVVAKTDPSQG
CEEEEEEECCCCCCCHHHHHHHHHEECCCCEEEECCEEEEECCCCCCEEEEEEECCCCCC
AAGISLIVVEADRAGFRRGKVLDKIGQRGQDTSELFFDEVRVPRSHLLGQAEGQGFIQLM
CCCEEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHH
TQLPQERLIVAVGAVAAMELALEQTLKYTREREAFGRPVFGFQNTKFTLAEAATETRIAR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHH
VFLDYCIDLHLAGQLDVQTVAMAKWWTTERAMKVLDDCMQLHGGYGYMTEYPISRLWVDQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHH
RVQKIYAGTNEVMKEIISRSL
HHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSPISPWMNAELLELRDLAAKFFSAELAPHANRFADQHHVDRELWNRAGELGLLCMSIP
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
EEYGGGGGTFAHEAVVLEEQARIGDSSWGAGLHSGIVAHYILQYATEELRAQWLPKMASG
HHHCCCCCCHHHHHHEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EMIGAIAMTEPGTGSDLQSVKTKALLDGDEYVITGSKTFITNGQQADLIIVVAKTDPSQG
CEEEEEEECCCCCCCHHHHHHHHHEECCCCEEEECCEEEEECCCCCCEEEEEEECCCCCC
AAGISLIVVEADRAGFRRGKVLDKIGQRGQDTSELFFDEVRVPRSHLLGQAEGQGFIQLM
CCCEEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHH
TQLPQERLIVAVGAVAAMELALEQTLKYTREREAFGRPVFGFQNTKFTLAEAATETRIAR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHH
VFLDYCIDLHLAGQLDVQTVAMAKWWTTERAMKVLDDCMQLHGGYGYMTEYPISRLWVDQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHH
RVQKIYAGTNEVMKEIISRSL
HHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]