Click here to switch to the map view.

The map label for this gene is ahpC [C]

Identifier: 169628975

GI number: 169628975

Start: 1885231

End: 1885692

Strand: Direct

Name: ahpC [C]

Synonym: MAB_1887

Alternate gene names: 169628975

Gene position: 1885231-1885692 (Clockwise)

Preceding gene: 169628974

Following gene: 169628976

Centisome position: 37.2

GC content: 64.94

Gene sequence:

>462_bases
ATGCTGCCTGTTGGCACCGTCGCCCCCGACTTCACCCTGCGCAACCAAAACAACCAGCCCGTCAGCCTTAGCGATTTCCG
GGGCAAGAAGGCCGTGCTGCTGGTGTTCTTCCCGCTGGCCTTCACCGGCGTGTGCCAGGGCGAGCTGGACCATGTGCGCG
ACCACATCGGCGACTTCGAGAACGACGAGGTGCAGATCATCGCGCTGTCGGTGAGCGCCGGGCCGATCCACAAGATCTGG
TCCAGCTACAGCGGCTTCACCTTCCCGATCCTGTCCGATTTCTGGCCCCACGGCGCCGTCGCCGAGGCGTACGGGGTGCT
CAACGAGAAGGCCGGGTATCCGAACCGCGGCACCTTCGTGGTGGATGCCGACGGAATCATCCGATTCGCCGAAATGCTGG
ACCCCGGGCAAGCCCGTGACCAGGCGGGTTGGGTACAGGCGCTGGCCGCGCTACATTCGTGA

Upstream 100 bases:

>100_bases
CTCAACCTGGGGGATTGGAGCGCGACGCGGCTGGTGCAGCCCAAATCATCCCGGGGCGGGCGGCGATGAGCGCTCGCGCG
AAGAGCAGAAGGTCTCGCTA

Downstream 100 bases:

>100_bases
GCTGATTCCCACGTTGGTCACGACGTGGACCGGGCGTGTAGCTCAGTGGTAGAGCTCTGGTTTTACACACCAGCGGTCGG
GGGTTCGAAACCCTCCGCGC

Product: peroxiredoxin (thioredoxin reductase) AhpE

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MLPVGTVAPDFTLRNQNNQPVSLSDFRGKKAVLLVFFPLAFTGVCQGELDHVRDHIGDFENDEVQIIALSVSAGPIHKIW
SSYSGFTFPILSDFWPHGAVAEAYGVLNEKAGYPNRGTFVVDADGIIRFAEMLDPGQARDQAGWVQALAALHS

Sequences:

>Translated_153_residues
MLPVGTVAPDFTLRNQNNQPVSLSDFRGKKAVLLVFFPLAFTGVCQGELDHVRDHIGDFENDEVQIIALSVSAGPIHKIW
SSYSGFTFPILSDFWPHGAVAEAYGVLNEKAGYPNRGTFVVDADGIIRFAEMLDPGQARDQAGWVQALAALHS
>Mature_153_residues
MLPVGTVAPDFTLRNQNNQPVSLSDFRGKKAVLLVFFPLAFTGVCQGELDHVRDHIGDFENDEVQIIALSVSAGPIHKIW
SSYSGFTFPILSDFWPHGAVAEAYGVLNEKAGYPNRGTFVVDADGIIRFAEMLDPGQARDQAGWVQALAALHS

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG1225

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=136, Percent_Identity=32.3529411764706, Blast_Score=67, Evalue=6e-12,
Organism=Homo sapiens, GI32455266, Length=136, Percent_Identity=32.3529411764706, Blast_Score=67, Evalue=6e-12,
Organism=Homo sapiens, GI32455264, Length=136, Percent_Identity=32.3529411764706, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786822, Length=142, Percent_Identity=30.2816901408451, Blast_Score=65, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357347, Length=149, Percent_Identity=32.2147651006711, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17738015, Length=131, Percent_Identity=33.587786259542, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24656348, Length=137, Percent_Identity=32.8467153284672, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17864676, Length=137, Percent_Identity=32.8467153284672, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16672; Mature: 16672

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVGTVAPDFTLRNQNNQPVSLSDFRGKKAVLLVFFPLAFTGVCQGELDHVRDHIGDFE
CCCCCCCCCCEEEECCCCCCEEHHCCCCCEEEEEEEEHHHHHHCCCCHHHHHHHHHCCCC
NDEVQIIALSVSAGPIHKIWSSYSGFTFPILSDFWPHGAVAEAYGVLNEKAGYPNRGTFV
CCCEEEEEEEECCCHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEE
VDADGIIRFAEMLDPGQARDQAGWVQALAALHS
EECCHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPVGTVAPDFTLRNQNNQPVSLSDFRGKKAVLLVFFPLAFTGVCQGELDHVRDHIGDFE
CCCCCCCCCCEEEECCCCCCEEHHCCCCCEEEEEEEEHHHHHHCCCCHHHHHHHHHCCCC
NDEVQIIALSVSAGPIHKIWSSYSGFTFPILSDFWPHGAVAEAYGVLNEKAGYPNRGTFV
CCCEEEEEEEECCCHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEE
VDADGIIRFAEMLDPGQARDQAGWVQALAALHS
EECCHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]