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The map label for this gene is yngJ [H]

Identifier: 169628939

GI number: 169628939

Start: 1849335

End: 1850474

Strand: Direct

Name: yngJ [H]

Synonym: MAB_1851

Alternate gene names: 169628939

Gene position: 1849335-1850474 (Clockwise)

Preceding gene: 169628937

Following gene: 169628944

Centisome position: 36.5

GC content: 63.51

Gene sequence:

>1140_bases
ATGACGTTCTCGTCCGAACACGACGACTTTCGCCGCACTATCCGCAGGTACATTGAGGAAAAGATCAACCCCCGCGTCGA
CGAGTGGGAACGCGAGCAGATGATGCCGCTGCACGAGGTGATCGCCGATATGGCCAAGCTCGGATTCGTCGGCCTGGAAT
ACGACCCTGAATACGGCGGACAAGGAGCGGATCACCTCTTCACGCTGGTCCTTGCCGAGGAACTCGGCCGGGTGGATCAC
GGGTCCTTTCCGATGGCCTTCGGGGTTCACGTCGCGATGGCCACCCCCTCGCTGCACAAACACGGCAGCGATGAGCTCAA
GCGCGAGTTCCTGGCTCCGGCCTTGCGCGGTGAGCAGATCGCGGCGATTGCGGTGACCGAGCCCGACGCCGGGTCCGATG
TGGCGGGCATCAAGACTCATGCCCGGCGTGACGGTGATGACTGGGTGATCAACGGCTCGAAGATGTTCATCACCAACTCC
GTTCAGGCCGACTGGTTGTGCGTGCTGGCCCGCACCTCCGATGAGGGTGGCTACGCGGGCATGAGTCAGATCATCGTTCC
GACCAAGGCCCCCGGGTACGAGGTCCGCAAGCTGGACAAGCTGGGCATGCACGCCTCCGACACCGGTCTGATCACCTTCG
ACGATGTCCGGGTGCCGGTGTCCAACACCATCGGCGAGATCGGCCGCGGGTTTCAGCAGCAGATGTCGCAGTTCGTCATG
GAGCGCATGTTCGGCGCGTACGGCATCCCCGCGAGTGTCAACCGGGCGCTACAGCGCACCAAGGAATATGCGTTGGCGCG
CCACGTTTTTGGCAAGCCGCTGACCAAGAACCAGCATCTGGCCTACCAATACGCGGGGCTGGCGGCGCGGGCCGACATGC
TGGAGGTCTACAACCGTGACATCGCCGAGCGGTACATGGCGGGGGAGAACGTGACCCGCAAGGTCACCATCGCCAAACTG
ACCGCCGGGCCGCTGGTCCGCGAGGCCGGCGATTGGTGCCTGCAGGTGCACGGCGGCATGGGGTATATGACCGAGACGTG
GACATCGCGATTCTTCCGGGATCAGCGTCTGCTCAGCATCGGCGGCGGTGCCGACGAGGTGATGATGCGGGTCCTATCCC
AGATCGACGGATTCTCCTGA

Upstream 100 bases:

>100_bases
TGGCACACCTCCAACGGACCGCGACGACCGCCGTCCTCCATCATGTTAGCTCGCGTGGCTGAGGCAAGATGGCCAGCGAC
ACCTACACGAGGAGAGACCG

Downstream 100 bases:

>100_bases
TGCCGCGGGTTTCGGTGTGAAGCACAGTCCGAGTTGCCCGCCTCTATGCGACAAACCGGCGTGCCCGCCGAGTTGTCGCA
TAGACGCGGGCACCTAGGTG

Product: acyl-CoA dehydrogenase FadE

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MTFSSEHDDFRRTIRRYIEEKINPRVDEWEREQMMPLHEVIADMAKLGFVGLEYDPEYGGQGADHLFTLVLAEELGRVDH
GSFPMAFGVHVAMATPSLHKHGSDELKREFLAPALRGEQIAAIAVTEPDAGSDVAGIKTHARRDGDDWVINGSKMFITNS
VQADWLCVLARTSDEGGYAGMSQIIVPTKAPGYEVRKLDKLGMHASDTGLITFDDVRVPVSNTIGEIGRGFQQQMSQFVM
ERMFGAYGIPASVNRALQRTKEYALARHVFGKPLTKNQHLAYQYAGLAARADMLEVYNRDIAERYMAGENVTRKVTIAKL
TAGPLVREAGDWCLQVHGGMGYMTETWTSRFFRDQRLLSIGGGADEVMMRVLSQIDGFS

Sequences:

>Translated_379_residues
MTFSSEHDDFRRTIRRYIEEKINPRVDEWEREQMMPLHEVIADMAKLGFVGLEYDPEYGGQGADHLFTLVLAEELGRVDH
GSFPMAFGVHVAMATPSLHKHGSDELKREFLAPALRGEQIAAIAVTEPDAGSDVAGIKTHARRDGDDWVINGSKMFITNS
VQADWLCVLARTSDEGGYAGMSQIIVPTKAPGYEVRKLDKLGMHASDTGLITFDDVRVPVSNTIGEIGRGFQQQMSQFVM
ERMFGAYGIPASVNRALQRTKEYALARHVFGKPLTKNQHLAYQYAGLAARADMLEVYNRDIAERYMAGENVTRKVTIAKL
TAGPLVREAGDWCLQVHGGMGYMTETWTSRFFRDQRLLSIGGGADEVMMRVLSQIDGFS
>Mature_378_residues
TFSSEHDDFRRTIRRYIEEKINPRVDEWEREQMMPLHEVIADMAKLGFVGLEYDPEYGGQGADHLFTLVLAEELGRVDHG
SFPMAFGVHVAMATPSLHKHGSDELKREFLAPALRGEQIAAIAVTEPDAGSDVAGIKTHARRDGDDWVINGSKMFITNSV
QADWLCVLARTSDEGGYAGMSQIIVPTKAPGYEVRKLDKLGMHASDTGLITFDDVRVPVSNTIGEIGRGFQQQMSQFVME
RMFGAYGIPASVNRALQRTKEYALARHVFGKPLTKNQHLAYQYAGLAARADMLEVYNRDIAERYMAGENVTRKVTIAKLT
AGPLVREAGDWCLQVHGGMGYMTETWTSRFFRDQRLLSIGGGADEVMMRVLSQIDGFS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=32.2666666666667, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=29.9465240641711, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=29.5212765957447, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI4557233, Length=368, Percent_Identity=30.9782608695652, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI4557231, Length=381, Percent_Identity=30.4461942257218, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI187960098, Length=381, Percent_Identity=30.4461942257218, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=30, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=30, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI21361497, Length=377, Percent_Identity=28.9124668435013, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI76496475, Length=371, Percent_Identity=28.3018867924528, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI4557235, Length=371, Percent_Identity=28.3018867924528, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI7669494, Length=289, Percent_Identity=30.7958477508651, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI4503943, Length=289, Percent_Identity=30.7958477508651, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI38505218, Length=364, Percent_Identity=26.6483516483516, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI48976061, Length=391, Percent_Identity=25.3196930946292, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI211971008, Length=391, Percent_Identity=25.3196930946292, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI87081958, Length=336, Percent_Identity=30.952380952381, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1786223, Length=376, Percent_Identity=27.6595744680851, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=42.1333333333333, Blast_Score=291, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=42.6666666666667, Blast_Score=285, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=29.4429708222812, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=29.2553191489362, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=30.3191489361702, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17534899, Length=378, Percent_Identity=30.6878306878307, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=29.8387096774194, Blast_Score=161, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17569725, Length=385, Percent_Identity=29.0909090909091, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17533517, Length=374, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71985184, Length=347, Percent_Identity=30.835734870317, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=30.3754266211604, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71982178, Length=265, Percent_Identity=30.5660377358491, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=32.6086956521739, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=277, Percent_Identity=28.8808664259928, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71985192, Length=246, Percent_Identity=32.1138211382114, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=343, Percent_Identity=25.9475218658892, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=26.7782426778243, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355753, Length=367, Percent_Identity=31.0626702997275, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=29.0322580645161, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=29.2225201072386, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24666513, Length=381, Percent_Identity=30.7086614173228, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24660351, Length=369, Percent_Identity=31.7073170731707, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI281363737, Length=333, Percent_Identity=27.6276276276276, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI19920834, Length=288, Percent_Identity=29.8611111111111, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42230; Mature: 42098

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSSEHDDFRRTIRRYIEEKINPRVDEWEREQMMPLHEVIADMAKLGFVGLEYDPEYGG
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCC
QGADHLFTLVLAEELGRVDHGSFPMAFGVHVAMATPSLHKHGSDELKREFLAPALRGEQI
CCHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEEECCHHHHCCCHHHHHHHHHHHHCCCCE
AAIAVTEPDAGSDVAGIKTHARRDGDDWVINGSKMFITNSVQADWLCVLARTSDEGGYAG
EEEEEECCCCCCCCHHHHHHHCCCCCCEEEECCEEEEECCCCCCEEEEEEEECCCCCCCC
MSQIIVPTKAPGYEVRKLDKLGMHASDTGLITFDDVRVPVSNTIGEIGRGFQQQMSQFVM
CCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEECCEECCHHHHHHHHHHHHHHHHHHHHH
ERMFGAYGIPASVNRALQRTKEYALARHVFGKPLTKNQHLAYQYAGLAARADMLEVYNRD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IAERYMAGENVTRKVTIAKLTAGPLVREAGDWCLQVHGGMGYMTETWTSRFFRDQRLLSI
HHHHHHCCCCCEEEEEEEEECCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCHHEEE
GGGADEVMMRVLSQIDGFS
CCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TFSSEHDDFRRTIRRYIEEKINPRVDEWEREQMMPLHEVIADMAKLGFVGLEYDPEYGG
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCC
QGADHLFTLVLAEELGRVDHGSFPMAFGVHVAMATPSLHKHGSDELKREFLAPALRGEQI
CCHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEEECCHHHHCCCHHHHHHHHHHHHCCCCE
AAIAVTEPDAGSDVAGIKTHARRDGDDWVINGSKMFITNSVQADWLCVLARTSDEGGYAG
EEEEEECCCCCCCCHHHHHHHCCCCCCEEEECCEEEEECCCCCCEEEEEEEECCCCCCCC
MSQIIVPTKAPGYEVRKLDKLGMHASDTGLITFDDVRVPVSNTIGEIGRGFQQQMSQFVM
CCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEECCEECCHHHHHHHHHHHHHHHHHHHHH
ERMFGAYGIPASVNRALQRTKEYALARHVFGKPLTKNQHLAYQYAGLAARADMLEVYNRD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IAERYMAGENVTRKVTIAKLTAGPLVREAGDWCLQVHGGMGYMTETWTSRFFRDQRLLSI
HHHHHHCCCCCEEEEEEEEECCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCHHEEE
GGGADEVMMRVLSQIDGFS
CCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]