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The map label for this gene is prtS [H]

Identifier: 169628937

GI number: 169628937

Start: 1847878

End: 1848921

Strand: Direct

Name: prtS [H]

Synonym: MAB_1849

Alternate gene names: 169628937

Gene position: 1847878-1848921 (Clockwise)

Preceding gene: 169628936

Following gene: 169628939

Centisome position: 36.47

GC content: 64.94

Gene sequence:

>1044_bases
ATGTGCCAGCGTTTCATCATCCCTCCGGCCGTGCTGTCCCGATTGGCCGAGGACGGCGATATCGCCGAAGACTCACGCGC
CGCCCTCTCGGCCACCGCGGCATGCGAATTGTCTTGGCGCACCTTGCGCAATGCGCACACGCGCGCCACTCAGGCCAGCC
TCCTGACAAGCCGGGCCGCCGCCCTCGGAGCCGCCGCCACCGGGCTGGCCAAGGTTCCCGAGACGCCCGTGTTCGATTGC
CGGCAGACCACCTCGTTGCCGGGCGTGGCCGTGGCCGACCCTGCCACCTCCAAGGACGCCACGGCACAACGGGCGTTCGA
CGAGACGGTGGCGGTCGCAGAGTTCTACCGGAACTGCTTTGGGCGCAACTCCGTTGACAACGCGGGGATGACCCTGGTGT
CATCCATTCATTACGGCGTCAAGTACTCCAATGCGTTCTGGAACGGTTCGCAGATGGCCTACGGGGACGGTGACGGCCAG
ATATTTCTGGACTTCACCAAGTCCAACGATGTGATCGGTCATGAACTGACACACGGGGTCACGCAATTCACCGCCGGCCT
GGATTACGAGAACGAAGCGGGGGCATTGAACGAAAGTGTCTCGGACGTCTTCGGTTCGATGTTCCGGCAATGGCAGGGGC
AGCAGAGCGCGGACAAGGCCGACTGGCTGATCGGCAAGGACATCCTGGGACCGCGCGCCCTCGACAAGGGATACACGTGC
CTACGCGATATGGCCGACCCCGCCGCCGCGCACTGCCTCTCACCGCAGCCCTCGCACTACCGCGACTACGTGCCGGGCAG
TGATCCGCATGAGGGCAGCGGCATCCCCAATCACGCGTTCTACCTGGCCGCCACCAAGTACGGCTCCCACTCCTGGGAGG
CCGTGGGAACGGTCTGGTACCAGGCTCTCACCAGCCCGAAGGCAACGAAAAACATGACATTCAAGGCCTTCGCGAAACTC
ACCCGGCAGATCGCCGCGGGCCGGACCGGGGCAGACTCGCCACAGGCGGCGATCGATGAGGCCTGGACCGAGGTGGGGCT
CTAG

Upstream 100 bases:

>100_bases
TCAGGCAGTGTGTCCAAGAACGGATCTGACGAACCGGACTTGACATTTCACCGCTCGCGCGATCAGCGCGCATGGGCGCG
AGCGGGTAGGGTCGGTTGGA

Downstream 100 bases:

>100_bases
TCGTCCTGCCAGAAGTCGGGGCAGGAGATGTCGACGTAGACGGTGGTGAAGGAGTCGACTGGCTTGCCCGAACGGTTCGG
GTTGTGCACCGCCAGCACCC

Product: putative metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MCQRFIIPPAVLSRLAEDGDIAEDSRAALSATAACELSWRTLRNAHTRATQASLLTSRAAALGAAATGLAKVPETPVFDC
RQTTSLPGVAVADPATSKDATAQRAFDETVAVAEFYRNCFGRNSVDNAGMTLVSSIHYGVKYSNAFWNGSQMAYGDGDGQ
IFLDFTKSNDVIGHELTHGVTQFTAGLDYENEAGALNESVSDVFGSMFRQWQGQQSADKADWLIGKDILGPRALDKGYTC
LRDMADPAAAHCLSPQPSHYRDYVPGSDPHEGSGIPNHAFYLAATKYGSHSWEAVGTVWYQALTSPKATKNMTFKAFAKL
TRQIAAGRTGADSPQAAIDEAWTEVGL

Sequences:

>Translated_347_residues
MCQRFIIPPAVLSRLAEDGDIAEDSRAALSATAACELSWRTLRNAHTRATQASLLTSRAAALGAAATGLAKVPETPVFDC
RQTTSLPGVAVADPATSKDATAQRAFDETVAVAEFYRNCFGRNSVDNAGMTLVSSIHYGVKYSNAFWNGSQMAYGDGDGQ
IFLDFTKSNDVIGHELTHGVTQFTAGLDYENEAGALNESVSDVFGSMFRQWQGQQSADKADWLIGKDILGPRALDKGYTC
LRDMADPAAAHCLSPQPSHYRDYVPGSDPHEGSGIPNHAFYLAATKYGSHSWEAVGTVWYQALTSPKATKNMTFKAFAKL
TRQIAAGRTGADSPQAAIDEAWTEVGL
>Mature_347_residues
MCQRFIIPPAVLSRLAEDGDIAEDSRAALSATAACELSWRTLRNAHTRATQASLLTSRAAALGAAATGLAKVPETPVFDC
RQTTSLPGVAVADPATSKDATAQRAFDETVAVAEFYRNCFGRNSVDNAGMTLVSSIHYGVKYSNAFWNGSQMAYGDGDGQ
IFLDFTKSNDVIGHELTHGVTQFTAGLDYENEAGALNESVSDVFGSMFRQWQGQQSADKADWLIGKDILGPRALDKGYTC
LRDMADPAAAHCLSPQPSHYRDYVPGSDPHEGSGIPNHAFYLAATKYGSHSWEAVGTVWYQALTSPKATKNMTFKAFAKL
TRQIAAGRTGADSPQAAIDEAWTEVGL

Specific function: Metalloprotease involved in the inhibition of insect antibacterial peptides. Reduces the antibacterial activity of G.mellonella hemolymph by 50%. Reduces the antibacterial activity of cecropin A by 80% and completely inhibits cecropin B [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013856
- InterPro:   IPR001570 [H]

Pfam domain/function: PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: NA

Molecular weight: Translated: 37217; Mature: 37217

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCQRFIIPPAVLSRLAEDGDIAEDSRAALSATAACELSWRTLRNAHTRATQASLLTSRAA
CCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGAAATGLAKVPETPVFDCRQTTSLPGVAVADPATSKDATAQRAFDETVAVAEFYRNCF
HHHHHHHHHHCCCCCCCCCCHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRNSVDNAGMTLVSSIHYGVKYSNAFWNGSQMAYGDGDGQIFLDFTKSNDVIGHELTHGV
CCCCCCHHHHHHHHHHHHCEEECCCEECCCEEEEECCCCEEEEEECCCCCCCHHHHHHHH
TQFTAGLDYENEAGALNESVSDVFGSMFRQWQGQQSADKADWLIGKDILGPRALDKGYTC
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHCCCHHHHHHHHH
LRDMADPAAAHCLSPQPSHYRDYVPGSDPHEGSGIPNHAFYLAATKYGSHSWEAVGTVWY
HHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHH
QALTSPKATKNMTFKAFAKLTRQIAAGRTGADSPQAAIDEAWTEVGL
HHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MCQRFIIPPAVLSRLAEDGDIAEDSRAALSATAACELSWRTLRNAHTRATQASLLTSRAA
CCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGAAATGLAKVPETPVFDCRQTTSLPGVAVADPATSKDATAQRAFDETVAVAEFYRNCF
HHHHHHHHHHCCCCCCCCCCHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRNSVDNAGMTLVSSIHYGVKYSNAFWNGSQMAYGDGDGQIFLDFTKSNDVIGHELTHGV
CCCCCCHHHHHHHHHHHHCEEECCCEECCCEEEEECCCCEEEEEECCCCCCCHHHHHHHH
TQFTAGLDYENEAGALNESVSDVFGSMFRQWQGQQSADKADWLIGKDILGPRALDKGYTC
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHCCCHHHHHHHHH
LRDMADPAAAHCLSPQPSHYRDYVPGSDPHEGSGIPNHAFYLAATKYGSHSWEAVGTVWY
HHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHH
QALTSPKATKNMTFKAFAKLTRQIAAGRTGADSPQAAIDEAWTEVGL
HHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA