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The map label for this gene is era [H]

Identifier: 169628762

GI number: 169628762

Start: 1699586

End: 1700500

Strand: Direct

Name: era [H]

Synonym: MAB_1672

Alternate gene names: 169628762

Gene position: 1699586-1700500 (Clockwise)

Preceding gene: 169628761

Following gene: 169628763

Centisome position: 33.54

GC content: 64.26

Gene sequence:

>915_bases
GTGAGCTCGCCGGAATTCCGTTCCGGTTTCGTCTGTTTCGTCGGGAGGCCGAACACCGGCAAGTCGACGCTGACCAACGC
GCTGGTCGGGCAGAAGGTGGCCATCACGTCGAACCGGCCGCAGACGACCCGCCACACCATTCGCGGCATCGTGCACCGCG
AGAACTTCCAGATCGTGCTCGTCGACACCCCGGGGCTGCACCGGCCGCGCACGCTGCTCGGTCAACGGCTCAACGACCTT
GTGCGCGATACGTATTCCGAGGTCGACGTGATCGGGTTGTGTATCCCGGCCGACGAGGGTATCGGGCCGGGGGACAAGTG
GATCTACGAACAGATCAAGCTCGTCGCGCCGCGCACCACGCTGATCGCGATCGTCACCAAGATCGACAAGGTGAGCAAGG
AGCGGGTGGCCGAGCAGCTGCTGTCGGTGTCACAGCTTGTCGGTAAGGAGGTGGACATCGTCCCGGTATCGGCGGTGTCG
GGAGCCCAAGTCGAGGTGCTGACAGAGGTTTTGGCGTCCAAGCTGCAGCCTGGTCCGGCGTTCTATCCCGATGGTGAATT
GACCGATGAGCCCGAAGAGGTGCTCATGGCCGAGCTCATTCGTGAGGCCGCGCTCGAGGGCGTGCGGGACGAGCTGCCGC
ACTCGCTGGCGGTGGTGATCGACGAGTGCAGCGAGCGCGAGGGGCGTCCCGAGGGCTCGGAGCTGATTGATGTGCACGCG
ATTCTCTACGTCGAGCGGGACAGTCAAAAGGGCATCGTCATCGGCAAGGGCGGCGCCCGGCTACGCGAGGTGGGGACCAA
CGCGCGTACGCAGATCGAAAAGCTGCTCGGCACAAAGGTGTTCCTGGATCTGCGGGTCAAGGTCGCCAAGAATTGGCAGC
GCGACCCCAAGCAGCTCGGCAAGCTGGGGTTCTGA

Upstream 100 bases:

>100_bases
GTGGTTCACATGAAGACCCGGGTATCGCGGCGGTACGGGAACTGTCGCCGTCGGCGACGGTCATCGTGACCGACCGCACC
GGTGTGCCCGCGGGGCAATT

Downstream 100 bases:

>100_bases
GCGACCCGCAGCCCTCCCCGCCGACACGCCGTGTTATGCGTTGGCTACTCGCGAAATACATCAGAAACCGTAGTTTCGGT
GACTTGTCGGTACGCCGTGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSSPEFRSGFVCFVGRPNTGKSTLTNALVGQKVAITSNRPQTTRHTIRGIVHRENFQIVLVDTPGLHRPRTLLGQRLNDL
VRDTYSEVDVIGLCIPADEGIGPGDKWIYEQIKLVAPRTTLIAIVTKIDKVSKERVAEQLLSVSQLVGKEVDIVPVSAVS
GAQVEVLTEVLASKLQPGPAFYPDGELTDEPEEVLMAELIREAALEGVRDELPHSLAVVIDECSEREGRPEGSELIDVHA
ILYVERDSQKGIVIGKGGARLREVGTNARTQIEKLLGTKVFLDLRVKVAKNWQRDPKQLGKLGF

Sequences:

>Translated_304_residues
MSSPEFRSGFVCFVGRPNTGKSTLTNALVGQKVAITSNRPQTTRHTIRGIVHRENFQIVLVDTPGLHRPRTLLGQRLNDL
VRDTYSEVDVIGLCIPADEGIGPGDKWIYEQIKLVAPRTTLIAIVTKIDKVSKERVAEQLLSVSQLVGKEVDIVPVSAVS
GAQVEVLTEVLASKLQPGPAFYPDGELTDEPEEVLMAELIREAALEGVRDELPHSLAVVIDECSEREGRPEGSELIDVHA
ILYVERDSQKGIVIGKGGARLREVGTNARTQIEKLLGTKVFLDLRVKVAKNWQRDPKQLGKLGF
>Mature_303_residues
SSPEFRSGFVCFVGRPNTGKSTLTNALVGQKVAITSNRPQTTRHTIRGIVHRENFQIVLVDTPGLHRPRTLLGQRLNDLV
RDTYSEVDVIGLCIPADEGIGPGDKWIYEQIKLVAPRTTLIAIVTKIDKVSKERVAEQLLSVSQLVGKEVDIVPVSAVSG
AQVEVLTEVLASKLQPGPAFYPDGELTDEPEEVLMAELIREAALEGVRDELPHSLAVVIDECSEREGRPEGSELIDVHAI
LYVERDSQKGIVIGKGGARLREVGTNARTQIEKLLGTKVFLDLRVKVAKNWQRDPKQLGKLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=310, Percent_Identity=32.9032258064516, Blast_Score=164, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24646434, Length=314, Percent_Identity=23.2484076433121, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33394; Mature: 33263

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPEFRSGFVCFVGRPNTGKSTLTNALVGQKVAITSNRPQTTRHTIRGIVHRENFQIVL
CCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHEEECCEEEEE
VDTPGLHRPRTLLGQRLNDLVRDTYSEVDVIGLCIPADEGIGPGDKWIYEQIKLVAPRTT
EECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHH
LIAIVTKIDKVSKERVAEQLLSVSQLVGKEVDIVPVSAVSGAQVEVLTEVLASKLQPGPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCC
FYPDGELTDEPEEVLMAELIREAALEGVRDELPHSLAVVIDECSEREGRPEGSELIDVHA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHEEEEE
ILYVERDSQKGIVIGKGGARLREVGTNARTQIEKLLGTKVFLDLRVKVAKNWQRDPKQLG
EEEEEECCCCCEEEECCCCHHHHHCCCHHHHHHHHHCCHHEEHHHHHHHHCCCCCHHHHC
KLGF
CCCC
>Mature Secondary Structure 
SSPEFRSGFVCFVGRPNTGKSTLTNALVGQKVAITSNRPQTTRHTIRGIVHRENFQIVL
CCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHEEECCEEEEE
VDTPGLHRPRTLLGQRLNDLVRDTYSEVDVIGLCIPADEGIGPGDKWIYEQIKLVAPRTT
EECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHH
LIAIVTKIDKVSKERVAEQLLSVSQLVGKEVDIVPVSAVSGAQVEVLTEVLASKLQPGPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCC
FYPDGELTDEPEEVLMAELIREAALEGVRDELPHSLAVVIDECSEREGRPEGSELIDVHA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHEEEEE
ILYVERDSQKGIVIGKGGARLREVGTNARTQIEKLLGTKVFLDLRVKVAKNWQRDPKQLG
EEEEEECCCCCEEEECCCCHHHHHCCCHHHHHHHHHCCHHEEHHHHHHHHCCCCCHHHHC
KLGF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA